Qhov sib txawv tseem ceeb ntawm chlorpheniramine thiab diphenhydramine yog tias chlorpheniramine feem ntau yog siv los ntawm qhov ncauj li ntsiav tshuaj, thiab qhov ntau npaum li cas yog tsawg, whereas diphenhydramine yog muab los ntawm qhov ncauj lossis txhaj tshuaj, thiab qhov ntau npaum li qhov sib piv.
Ob qho tib si chlorpheniramine thiab diphenhydramine yog qhov tseem ceeb xws li tshuaj tiv thaiv kab mob uas tuaj yeem kho cov tsos mob ntawm kev ua xua, hay fever, thiab mob khaub thuas.
Chlorpheniramine yog dab tsi?
Chlorpheniramine yog ib hom tshuaj tiv thaiv kab mob uas muaj txiaj ntsig zoo hauv kev txo cov tsos mob ua xua, ua npaws, thiab mob khaub thuas. Cov tsos mob uas nws tuaj yeem txo tau muaj xws li pob khaus, qhov muag dej, khaus qhov muag / qhov ntswg / caj pas / tawv nqaij, hnoos, qhov ntswg, thiab txham.
Chlorpheniramine ua haujlwm los ntawm kev thaiv qee yam khoom ntuj uas lub cev ua thaum muaj kev fab tshuaj. Nws kuj tseem tuaj yeem pab ua kom qhuav qee cov kua dej me me kom txo tau cov tsos mob, suav nrog qhov muag dej thiab qhov ntswg los ntawm kev thaiv lwm yam khoom ntuj tsim los ntawm lub cev: acetylcholine.
Daim duab 01: Cov Qauv Tshuaj ntawm Chlorpheniramine
Txawm li cas los xij, cov khoom no tsis pom zoo rau kev kho mob khaub thuas lossis hnoos hauv cov menyuam yaus (qis dua 6 xyoos). Tsis tas li ntawd, cov ntsiav tshuaj lossis cov ntsiav tshuaj ntawm cov tshuaj no tsis haum rau cov menyuam yaus hnub nyoog qis dua 12 xyoos. Cov khoom no tsis tuaj yeem ua kom luv lossis kho tus mob khaub thuas. Yog li ntawd, nws tuaj yeem ua rau muaj kev phiv loj heev thiab. Qee qhov kev mob tshwm sim ntawm cov tshuaj no suav nrog qaug zog, kiv taub hau, cem quav, mob plab, qhov muag tsis pom kev, thiab qhov ncauj qhuav / qhov ntswg / caj pas.
Cov tshuaj formula ntawm cov tshuaj no yog C16H19ClN2, thaum molar mass ntawm chlorpheniramine yog 274.79 g / mol. Nws muaj tsis zoo solubility nyob rau hauv dej, uas yog hais txog 0.55 g / 100 mL. Lub bioavailability ntawm chlorpheniramine yog nyob rau hauv thaj tsam ntawm 25 mus rau 50%, thiab nws txoj kev muaj peev xwm ntawm cov protein yog 72%. Tsis tas li ntawd, cov metabolism ntawm cov tshuaj no tshwm sim hauv daim siab, thiab kev tshem tawm ib nrab-lub neej yog li 13 - 43 teev. Kev tso tawm tshwm sim los ntawm lub raum.
Diphenhydramine yog dab tsi?
Diphenhydramine yog ib hom kev tsaug zog antihistamine uas muaj txiaj ntsig zoo hauv kev txo cov tsos mob ntawm kev ua xua, hay fever, thiab mob khaub thuas. Qhov no hu ua tsaug zog histamine vim nws tuaj yeem ua rau peb tsaug zog piv rau lwm cov tshuaj tiv thaiv kab mob. Cov tshuaj no muaj txiaj ntsig zoo rau cov teeb meem pw tsaug zog luv luv, suav nrog insomnia.
Muaj qee qhov kev mob tshwm sim ntawm kev siv cov tshuaj no, suav nrog qhov ncauj qhuav, tsaug zog, xeev siab, tsis qab los noj mov, ntuav, cem quav, thiab lwm yam. Txoj hauv kev ntawm kev tswj hwm ntawm diphenhydramine yog kev tswj hwm qhov ncauj, txhaj tshuaj rau hauv cov leeg, txhaj rau cov leeg, thiab siv rau ntawm daim tawv nqaij. Feem ntau, peb tuaj yeem tau txais cov txiaj ntsig siab tshaj plaws 2 teev tom qab noj tshuaj. Cov teebmeem no yuav kav ntev txog xya teev.
Daim duab 02: Cov Qauv Tshuaj ntawm Diphenhydramine
Cov tshuaj formula ntawm diphenhydramine yog C17H21NO. Molar mass yog 255.36 g / mol. Lub bioavailability ntawm cov tshuaj no yog nyob ib ncig ntawm 40-60%, thiab cov protein khi muaj peev xwm nyob ib ncig ntawm 99%. Cov metabolism hauv diphenhydramine tshwm sim hauv daim siab, thiab cov kua dej tawm tuaj yeem tshwm sim los ntawm cov zis lossis quav. Kev tshem tawm ib nrab-lub neej ntawm cov tshuaj no yog nyob ib ncig ntawm 2.4 - 13.5 teev.
Ntxiv mus, diphenhydramine yog diphenylmethane derivative. Nws yog analogous rau orphenadrine (uas yog ib qho tshuaj anticholinergic), nefopam (ib qho tshuaj analgesic), thiab tofenacin (ib qho tshuaj tiv thaiv kev nyuaj siab). Peb tuaj yeem txheeb xyuas cov tshuaj no hauv cov ntshav, ntshav, thiab ntshav. Cov txheej txheem peb tuaj yeem siv rau qhov kev kuaj pom no suav nrog roj chromatography, huab hwm coj spectrometry, thiab lwm yam. Qhov kev ntsuas no yog qhov tseem ceeb hauv kev saib xyuas kev kho mob, lees paub kev kuaj mob lom neeg, rau kev tsav tsheb tsis zoo, kev tshawb nrhiav kev tuag, thiab lwm yam.
Qhov txawv ntawm Chlorpheniramine thiab Diphenhydramine yog dab tsi?
Ob qho tib si chlorpheniramine thiab diphenhydramine yog qhov tseem ceeb xws li tshuaj tiv thaiv kab mob uas tuaj yeem kho cov tsos mob ua xua, ua npaws, thiab mob khaub thuas. Qhov sib txawv tseem ceeb ntawm chlorpheniramine thiab diphenhydramine yog tias chlorpheniramine feem ntau yog siv los ntawm qhov ncauj raws li cov ntsiav tshuaj, thiab qhov ntau npaum li cas tsawg, whereas diphenhydramine yog siv los ntawm qhov ncauj los yog txhaj tshuaj, thiab qhov ntau npaum li cas yog qhov sib piv siab.
Cov ntawv qhia hauv qab no nthuav tawm qhov sib txawv ntawm chlorpheniramine thiab diphenhydramine hauv daim ntawv teev npe rau kev sib piv ntawm ib sab.
Summary – Chlorpheniramine vs Diphenhydramine
Chlorpheniramine thiab diphenhydramine yog cov tshuaj tiv thaiv kab mob tseem ceeb. Qhov sib txawv tseem ceeb ntawm chlorpheniramine thiab diphenhydramine yog tias chlorpheniramine feem ntau yog siv los ntawm qhov ncauj raws li cov ntsiav tshuaj, thiab qhov ntau npaum li cas tsawg, whereas diphenhydramine yog siv los ntawm qhov ncauj los yog txhaj tshuaj, thiab qhov ntau npaum li cas yog qhov sib piv siab.
