Qhov sib txawv tseem ceeb ntawm nuclear lamina thiab nuclear matrix yog hais tias nuclear lamina yog ib tug ntom fibrillar network txuam nrog lub puab nto ntawm lub puab txheej ntawm lub nuclear thaum nuclear matrix yog ib tug fibrillar network pom thoob plaws hauv lub nucleus ntawm ib tug. eukaryotic cell.
Lub nucleus yog cov txheej txheem membrane uas muaj cov ntaub ntawv keeb kwm yav dhau los. Nws feem ntau tswj kev loj hlob thiab kev tsim tawm ntawm tes. Nws yog qhov tseem ceeb tshaj plaws organelle hauv eukaryotic hlwb thiab suav txog 10% ntawm tag nrho cov ntim ntawm lub cell. Cov qauv ntawm nucleus encompasses nuclear membrane (lub hnab ntawv), nucleoplasm, chromosomes, nucleolus, thiab fibrillar networks. Nuclear lamina thiab nuclear matrix yog ob qhov sib txawv fibrillar tes hauj lwm pom nyob rau hauv lub nucleus ntawm eukaryotic hlwb.
Nuclear Lamina yog dab tsi?
Nuclear Lamina yog qhov tseem ceeb fibrillar network cuam tshuam nrog sab hauv ntawm lub puab nuclear membrane ntawm lub eunaryotic cell. Nuclear lamina yog tsim los ntawm intermediate filaments thiab membrane-associated proteins. Lamins yog hom V intermediate filaments hauv nuclear lamina. Lamins tuaj yeem categorized li hom A (lamin A, C) lossis hom B (lamin B1, B2) raws li homology ntawm lawv cov DNA sequences, biochemical zog, thiab cellular localization thaum lub sij hawm ntawm tes. Ntxiv mus, nyob rau hauv vertebrate genome, muaj peb genes uas encoded rau lamins. Nuclear lamin-associated membrane proteins yog ib qho los yog peripheral type membrane proteins. Qhov tseem ceeb tshaj plaws lamins txuam nrog cov proteins yog polypeptides 1 thiab 2 (LAP1, LAP2), emerin, lamin B- receptor (LBR), otefin, thiab MAN1.
Daim duab 01: Nuclear Lamina
Muaj ntau txoj haujlwm ua los ntawm nuclear lamina: muab kev txhawb nqa tshuab thiab tswj hwm cov xwm txheej tseem ceeb hauv cellular xws li DNA replication thiab cell division. Tsis tas li ntawd, nws kuj koom nrog hauv lub koom haum chromatin thiab pab cov embedding ntawm nuclear pore complexes nyob rau hauv lub hnab ntawv nuclear.
Nuclear Matrix yog dab tsi?
Nuclear matrix yog ib lub network fibrillar pom nyob rau hauv lub nucleus ntawm eukaryotic cell. Nuclear matrix tuaj yeem pom meej meej tom qab ib txoj hauv kev tshwj xeeb ntawm kev rho tawm cov tshuaj. Nws muaj cov nuclei lamina, residual nucleoli, granular thiab fibrous matrix qauv nthuav dav thoob plaws hauv lub nucleus, thiab ribonucleoproteins. Nuclear matrix zoo ib yam li cytoskeleton ntawm lub cell.
Daim duab 02: Nuclear Matrix
Tsis tas li ntawd, nrog rau daim nyias nyias, nuclear matrix pab hauv kev npaj cov ntaub ntawv caj ces hauv lub cell. Tsis tas li ntawd, nws tseem yog lub luag haujlwm los tswj cov duab ntawm cov nucleus thiab lub koom haum spatial ntawm chromatin. Nws kuj koom nrog ntau cov txheej txheem ntawm tes, suav nrog DNA replication, kho, gene qhia, RNA thauj, cell signaling, cell txawv, cell cycle regulation, apoptosis, and carcinogenesis.
Dab tsi zoo sib xws ntawm Nuclear Lamina thiab Nuclear Matrix?
- Nuclear lamina thiab nuclear matrix yog ob qhov sib txawv fibrillar network hauv lub nucleus ntawm eukaryotic cell.
- Ob lub network fibrillar muaj nruab nrab filaments.
- Lawv muaj cov proteins tshwj xeeb.
- Lawv ua lub luag haujlwm tseem ceeb hauv cov hlwb eukaryotic hauv kev tswj cov qauv ntawm cov nucleus thiab lwm cov txheej txheem ntawm tes.
Qhov txawv ntawm Nuclear Lamina thiab Nuclear Matrix yog dab tsi?
Nuclear Lamina yog qhov tseem ceeb fibrillar network cuam tshuam nrog lub hnab ntawv sab hauv ntawm lub tsev pheeb suab hauv nucrix uas pom nyob hauv lub nucleus ntawm lub eukaryotic cell. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm nuclear lamina thiab nuclear matrix. Tsis tas li ntawd, nuclear lamina muaj cov proteins xws li polypeptides 1 thiab 2 (LAP1, LAP2), emerin, lamin B- receptor (LBR), otefin, thiab MAN1, tab sis nuclear matrix muaj cov proteins xws li lamin txuam cov proteins, cov txheej txheem proteins, chaperones, DNA. /RNA khi cov proteins, chromatin remodeling proteins, thiab transcriptions yam.
Cov hauv qab no qhia txog qhov sib txawv ntawm nuclear lamina thiab nuclear matrix nyob rau hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Nuclear Lamina vs Nuclear Matrix
Nuclear lamina thiab nuclear matrix yog cov xov tooj ntawm fibers pom nyob rau hauv lub nucleus ntawm eukaryotic hlwb. Nuclear Lamina yog ib qho tseem ceeb fibrillar network cuam tshuam nrog sab hauv ntawm lub puab tsaig nucrix pom sab hauv lub nucleus ntawm lub eunaryotic cell. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm nuclear lamina thiab nuclear matrix.
