Qhov sib txawv tseem ceeb ntawm histidine thiab histamine yog tias histidine yog ib qho α amino acid siv nyob rau hauv cov txheej txheem biosynthesis ntawm cov protein thaum histamine yog ib qho amine uas ua rau lub paj hlwb, qaum qaum, thiab tsev menyuam.
Histidine yog ib qho tseem ceeb amino acid hauv tib neeg. Nws yog tsim nyog rau kev loj hlob thiab kho cov ntaub so ntswg. Nws kuj tseem xav tau rau kev saib xyuas ntawm myelin sheaths uas tiv thaiv cov paj hlwb. Histidine yog xav tau rau kev tsim cov qe ntshav, thiab nws tiv thaiv cov ntaub so ntswg tiv thaiv kev puas tsuaj los ntawm hluav taws xob thiab hlau hnyav. Vim qhov kev ua ntawm histidine decarboxylase enzyme, histidine metabolizes rau hauv histamine. Histamine yog ib qho neurotransmitter. Nws plays ntau lub luag haujlwm hauv kev tiv thaiv kab mob, plab hnyuv, thiab kev ua haujlwm ntawm kev sib deev.
Histidine yog dab tsi?
Histidine yog α amino acid siv hauv biosynthesis ntawm cov protein. Tib neeg siv histidine ua tshuaj. Nws yog ib qho tseem ceeb rau cov me nyuam mos thiab cov laus. Nws yog encoded los ntawm cov noob caj noob ces codons CAU thiab CAC. Histidine muaj ib pawg α amino, pawg carboxylic, thiab imidazole sab saw. Nyob rau hauv physiological pH, histidine yog cais raws li ib tug zoo nqi amino acid. Cov amino acid no yog thawj zaug cais los ntawm tus kws kho mob German Albrecht Kossel thiab Swedish chemist Sven Gustaf Hedin hauv 1896.
Daim duab 01: L-Histidine
L-histidine yog ib qho tseem ceeb amino uas tsis yog synthesized hauv tib neeg. Tib neeg thiab lwm yam tsiaj yuav tsum noj histidine los ntawm kev noj cov protein uas muaj histidine. Cov kws tshawb fawb tau dav kawm txog biosynthesis ntawm histidine hauv prokaryotes xws li E. coli. Feem ntau, histidine synthesis hauv E.coli koom nrog yim cov khoom lag luam, thiab cov txheej txheem tshwm sim hauv kaum kauj ruam. Lub luag haujlwm tseem ceeb ntawm histidine nyob rau hauv lub cev yog tswj thiab pab metabolize cov kab mob xws li tooj liab, hlau, zinc, manganese, thiab molybdenum. Tsis tas li ntawd, nws yog siv los ntawm lub cev los ua cov tshuaj hormones tshwj xeeb thiab cov tshuaj metabolites uas cuam tshuam rau lub raum kev ua haujlwm, kev sib kis ntawm cov hlab ntsha, lub plab secretions, thiab lub cev tsis muaj zog. Nws tseem cuam tshuam rau kev kho thiab kev loj hlob ntawm cov ntaub so ntswg, tsim cov qe ntshav, thiab tiv thaiv cov hlab ntsha hlwb. Tsis tas li ntawd, histidine pab tsim cov enzymes sib txawv thiab cov tebchaw xws li metallothionein. Metallothionein tiv thaiv lub hlwb hlwb.
Histamine yog dab tsi?
Histamine yog ib qho amine uas ua rau lub paj hlwb, tus txha caj qaum, thiab lub tsev menyuam. Nws yog ib qho organic nitrogenous compound koom nrog hauv zos tiv thaiv kab mob, tswj kev ua haujlwm ntawm lub cev hauv plab. Histamine tau pom thawj zaug los ntawm kws tshuaj Askiv thiab kws kho mob hlwb Henry Dale hauv xyoo 1910. Txij li thaum nws tshawb pom, histamine tau suav tias yog ib qho tshuaj hormones hauv zos. Qhov no yog vim nws tsis muaj cov qog endocrine classic los zais nws. Ntxiv mus, histamine muaj ib lub nplhaib imidazole txuas mus rau ib txoj hlua ethylamine.
Daim duab 02: Histamine
Histamine feem ntau koom nrog cov lus teb inflammatory. Histamine muaj lub luag haujlwm tseem ceeb hauv kev sib haum xeeb ntawm khaus. Nws kuj tseem ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob rau cov kab mob txawv teb chaws. Histamine yog tsim los ntawm basophils thiab mast hlwb uas muaj nyob rau hauv cov ntaub so ntswg sib txuas. Nws nce permeability ntawm capillaries rau cov qe ntshav dawb thiab qee cov proteins. Qhov no tso cai rau lawv koom nrog cov kab mob hauv cov ntaub so ntswg.
Dab tsi zoo sib xws ntawm Histidine thiab Histamine?
- Histidine thiab histamine yog cov organic tebchaw.
- Ob lub tebchaw muaj ib pawg imidazole hauv cov qauv.
- Lawv tseem ceeb heev rau lub paj hlwb thiab kev tiv thaiv kab mob hauv lub cev.
- Ob lub tebchaw ua haujlwm tseem ceeb ntawm lub cev.
Qhov txawv ntawm Histidine thiab Histamine yog dab tsi?
Histidine yog ib qho α amino acid uas siv rau hauv cov txheej txheem biosynthesis ntawm cov protein, thaum histamine yog ib qho amine uas ua rau lub paj hlwb, qaum qaum, thiab tsev menyuam. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm histidine thiab histamine. Tsis tas li ntawd, cov mis molecular ntawm histidine yog C6H9N3O2. hos cov mis molecular ntawm histamine yog C5H9N3
Cov hauv qab no qhia txog qhov sib txawv ntawm histidine thiab histamine hauv daim ntawv teev npe rau ib sab ntawm kev sib piv.
Summary – Histidine vs Histamine
Histidine thiab histamine yog cov organic tebchaw uas tseem ceeb rau lub cev kev ua haujlwm ntawm lub cev. Histidine yog ib qho α amino acid uas siv rau hauv cov txheej txheem biosynthesis ntawm cov protein, thaum histamine yog ib qho amine uas ua rau lub paj hlwb, txha caj qaum, thiab tsev menyuam. Yog li, qhov no yog qhov txawv ntawm histidine thiab histamine.
