Qhov sib txawv tseem ceeb ntawm MCAS thiab histamine intolerance yog MCAS yog ib qho kev tiv thaiv kab mob uas cov hlwb mast tsis tsim nyog tso tawm cov tshuaj lom neeg ntau dhau, thaum histamine intolerance yog ib qho mob uas noj cov tshuaj histamine ntau hauv lub cev.
Histamine yog ib qho khoom siv nitrogenous koom nrog hauv zos tiv thaiv kab mob hauv tib neeg lub cev. Nws kuj tseem tswj cov haujlwm ntawm lub cev, ua lub luag haujlwm rau lub hlwb, tus txha caj qaum, thiab lub tsev menyuam. Nws tau pom nyob rau hauv 1910. Txij thaum ntawd los, nws tau raug suav hais tias yog ib qho tshuaj hormones hauv zos. Raws li ib feem tseem ceeb ntawm lub cev tiv thaiv kab mob, histamine tuaj yeem koom nrog hauv kev tiv thaiv kab mob xws li MCAS. Nws kuj tseem tuaj yeem koom nrog hauv cov xwm txheej tsis txaus ntseeg xws li histamine intolerance. MCAS thiab histamine intolerance yog ob yam mob uas tuaj yeem tshwm sim vim muaj ntau dhau ntawm histamine hauv lub cev.
MCAS yog dab tsi?
Mast cell activation syndrome (MCAS) yog ib hom kab mob mast cell activation disorder thiab ib qho kev tiv thaiv kab mob uas mast hlwb tsis tsim nyog tso tawm cov tshuaj lom neeg ntau dhau. Cov tshuaj no muaj xws li leukotrienes, histamines, prostaglandins, thiab tryptase. Tsis muaj cov laj thawj paub txog qhov teeb meem no, tab sis nws zoo nkaus li tau txais los ntawm qee tus neeg mob. Qhov no tej zaum yuav mob me. Txawm li cas los xij, nws tuaj yeem exacerbate vim muaj kev ntxhov siab hauv lub neej. Cov tsos mob muaj xws li hnoos, khaus, khaus, lub taub hau, raws plab, xeev siab, congestion, hnoos, thiab anaphylaxis.
Figure 01: MCAS
MCAS tseem yog qhov tsis nkag siab zoo. Tsis tas li ntawd, nws yog lub ntsiab lus ntawm kev tshawb fawb tam sim no. Cov mob no tuaj yeem kuaj tau hauv chav kuaj los ntawm kev ntsuas siab mast cell mediators. MCAS feem ntau nyuaj los txheeb xyuas vim muaj qhov sib txawv ntawm cov tsos mob. Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv tseem tsis tau tshaj tawm cov txheej txheem kuaj mob rau MCAS. Cov kev kho mob muaj xws li mast cell stabilizers (cromolyn sodium), H1-antihistamines (cetirizine), H2-antihistamines (ranitidine), antileukotrienes (montelukast), thiab tsis-steroidal anti-inflammatory tshuaj..
Histamine Intolerance yog dab tsi?
Histamine intolerance yog ib yam mob uas noj cov tshuaj histamine accumulates hauv lub cev. Lub intolerance feem ntau yog tshwm sim los ntawm gradual tsub zuj zuj ntawm extracellular histamine vim ib tug imbalance. Tib neeg ib txwm tsim cov tshuaj histamine nrog rau cov enzyme uas yog lub luag haujlwm rau kev rhuav tshem histamine: diamine oxidase. Diamine oxidase deficiency ua rau qhov tsis muaj peev xwm ntawm cov tshuaj histamine ua rau muaj kev tsis haum tshuaj histamine. Cov tsos mob muaj xws li mob taub hau, qhov ntswg congestion, qaug zog, khaus khaus, digestive teeb meem, kev coj khaub ncaws tsis xwm yeem, xeev siab, ntuav, mob plab, cov ntaub so ntswg o, lub plawv dhia tsis xwm yeem, ntxhov siab, nyuaj tswj lub cev kub, thiab kiv taub hau.
Daim duab 02: Histamine Intolerance
Kwv yees li 1% ntawm cov pejxeem muaj cov tshuaj histamine intolerance. Ntawm cov no, 80% yog cov neeg muaj hnub nyoog nruab nrab. Muaj qee yam khoom noj xws li cawv, zaub mov fermented, txiv hmab txiv ntoo qhuav, avocados, eggplants, spinach, shellfish, aged cheese, thiab lwm yam, muaj cov histamine siab, uas tuaj yeem ua rau muaj kev mob tshwm sim. Kev kuaj prick tuaj yeem siv los kuaj xyuas histamine intolerance. Cov kev kho mob muaj xws li tshuaj tiv thaiv kab mob, tshuaj pleev tshuaj steroid rau pob khaus thiab tshuaj ntxiv kom txo cov histamines xws li vitamin C, B6, Zn, Cu, magnesium, quercetin, DAO promoters.
Qhov Zoo sib xws ntawm MCAS thiab Histamine Intolerance yog dab tsi?
- MCAS thiab histamine intolerance yog ob yam mob uas tuaj yeem tshwm sim los ntawm kev sib sau ntawm histamine ntau dhau hauv lub cev.
- Nyob rau hauv ob qho tib si, cov neeg mob muaj pes tsawg tus mast hlwb hauv lub cev.
- Lawv ua rau cov tsos mob zoo sib xws xws li pob khaus, khaus khaus, thiab lwm yam.
- Antihistamines tuaj yeem siv los kho ob qho xwm txheej.
Qhov txawv ntawm MCAS thiab Histamine Intolerance yog dab tsi?
MCAS yog hom kab mob mast cell activation disorder uas yog ib qho kev tiv thaiv kab mob uas cov hlwb mast tso tawm cov tshuaj lom neeg ntau dhau, thaum cov tshuaj tsis haum rau cov tshuaj histamine yog ib qho mob uas noj cov tshuaj histamine accumulates hauv lub cev. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm MCAS thiab histamine intolerance. Tsis tas li ntawd, hauv MCAS, mast hlwb yog hyper-responsive, whereas, nyob rau hauv histamine intolerance, mast hlwb tsis hyper-responsive.
Cov infographic hauv qab no teev qhov sib txawv ntawm MCAS thiab histamine intolerance nyob rau hauv daim ntawv qhia rau ib sab ntawm kev sib piv.
Summary – MCAS vs Histamine Intolerance
Histamine yog ib qho khoom siv nitrogenous koom nrog hauv zos tiv thaiv kab mob hauv tib neeg lub cev. MCAS thiab histamine intolerance yog ob qho xwm txheej ntawm ntau dhau ntawm cov tshuaj histamine hauv lub cev. MCAS yog ib qho kev tiv thaiv kab mob uas cov qog hlwb tsis tsim nyog tso tawm cov tshuaj lom neeg ntau dhau, thaum histamine intolerance yog ib qho mob uas noj cov tshuaj histamine accumulates hauv lub cev. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm MCAS thiab histamine intolerance.
