Qhov sib txawv tseem ceeb ntawm osteogenesis imperfecta thiab osteoporosis yog osteogenesis imperfecta (Brittle Bone Disease) yog ib yam kab mob uas ua rau cov pob txha txawv txav, thaum osteoporosis yog kab mob caj dab uas ua rau poob pob txha ntom.
Cov pob txha ib txwm pab tib neeg txav mus los. Lawv kuj muab cov duab thiab kev txhawb nqa rau lub cev. Cov pob txha yog cov ntaub so ntswg nyob uas niaj hnub tsim kho thoob plaws lub neej. Thaum menyuam yaus thiab hluas, lub cev ua rau cov pob txha tshiab sai dua li nws tshem cov pob txha qub. Tab sis tom qab muaj hnub nyoog 20 xyoo, tib neeg lub cev poob pob txha sai dua li nws ua pob txha. Txhawm rau kom cov pob txha muaj zog, thaum muaj hnub nyoog laus, cov neeg yuav tsum tau noj cov calcium thiab vitamin D txaus thoob plaws hauv lawv lub neej. Cov tib neeg kuj yuav tsum tau tawm dag zog kom zoo thiab tsis txhob haus luam yeeb thiab haus dej kom cov pob txha muaj zog. Cov kab mob pob txha tuaj yeem ua rau cov pob txha tawg yooj yim. Osteogenesis imperfecta thiab osteoporosis yog ob hom kab mob sib txawv.
Dab tsi yog Osteogenesis Imperfecta (Brittle Bone Disease)?
Osteogenesis imperfecta yog ib yam kab mob caj ces uas ua rau cov pob txha txawv txav. Nws yog ib qho kev mob caj ces uas tshwm sim los ntawm kev yug los. Nws kuj yog lub npe hu ua brittle pob txha kab mob. Ib tug me nyuam yug los nrog tus kab mob no muaj cov pob txha mos uas nyiam tawg yooj yim heev. Cov pob txha tsis tsim ib txwm. Cov tsos mob thiab cov tsos mob tuaj yeem muaj xws li mob me mus rau qhov hnyav. Cov tsos mob yuav muaj xws li cov pob txha tawg yooj yim, pob txha deformities, discoloration ntawm qhov dawb ntawm lub qhov muag, chim-zoo li lub hauv siab, nkhaus nraub qaum, daim duab peb sab ntsej muag, xoob pob qij txha, cov leeg tsis muaj zog, thiab lwm yam.
Daim duab 01: Osteogenesis Imperfecta
Muaj tsawg kawg yog 8 ntau hom osteogenesis imperfecta. Osteogenesis imperfecta tuaj yeem tshwm sim vim muaj ntau yam kev hloov pauv. Kev hloov pauv hauv COL1A1 thiab COL1A2 noob ua rau kwv yees li 90% ntawm txhua tus neeg mob. Qee qhov kev hloov pauv tsis tu ncua. Yog li ntawd, cov menyuam mos uas yug los nrog kev hloov pauv muaj teeb meem hauv pob txha tsim vim yog cov ntaub so ntswg sib txuas. Qhov no yog tshwm sim los ntawm qhov tsis muaj hom 1 collagen. Feem ntau, collagen muaj nyob rau hauv cov pob txha, ligaments, thiab cov hniav uas ua rau lawv muaj zog. Thaum kawg, cov pob txha yuav tsis muaj zog. Tus mob no tuaj yeem kuaj tau los ntawm kev kuaj ntshav (rau kev hloov pauv ntawm cov noob caj noob ces) thiab kev kuaj pob txha pob txha (los ntawm X-ray). Cov kev xaiv kho mob muaj xws li kev ua haujlwm kho mob, kho lub cev, kho cov cuab yeej pab, kev kho qhov ncauj thiab kho hniav, thiab cov tshuaj kom txo qis pob txha thiab mob.
Osteoporosis yog dab tsi?
Osteoporosis yog ib yam kab mob caj ces uas ua rau poob pob txha. Osteoporosis ua rau cov pob txha tsis muaj zog thiab ua rau lawv muaj kev cuam tshuam rau kev puas tsuaj sai sai thiab npaj txhij txog. Osteoporosis txhais tau hais tias tib neeg tej zaum yuav muaj pob txha loj thiab tsis muaj zog. Cov poj niam muaj plaub zaug yuav kis tau osteoporosis ntau dua li cov txiv neej. Tsawg kawg yog 15 qhov kev hloov pauv noob tau raug lees paub tias yog pob txha pob txha ua rau cov noob hloov pauv. Qee cov noob caj noob ces koom nrog kev mob pob txha yog ESRI, LRP5, SOST, OPG, RANK, thiab RANKL. Tsis tas li ntawd, lwm 30 cov noob tau raug suav hais tias yog cov noob raug mob. Cov kev hloov pauv ntawm cov noob no tuaj yeem ua rau tsis sib xws lossis tau txais txiaj ntsig. Tsis tas li ntawd, cov noob no koom nrog hauv cov kev taw qhia tshuaj lom neeg uas cuam tshuam rau kev loj hlob ntawm cov hlwb thiab cov ntaub so ntswg. Lawv kuj koom nrog hauv kev tswj cov pob txha pob txha pob txha.
Daim duab 02: Osteoporosis
Cov tsos mob yuav muaj xws li mob nraub qaum, poob siab dhau sijhawm, lub cev khov kho, thiab cov pob txha tawg yooj yim. Feem ntau, qhov mob no tuaj yeem kuaj tau los ntawm X-ray, CT scan, txha nraub qaum CT, thiab pob txha ntom ntom. Cov kev xaiv kho mob suav nrog cov tshuaj xws li bisphosphonates, calcitonin, kev kho tshuaj hormone, RANK ligand inhibitor, xaiv cov tshuaj estrogen receptor modulators, thiab parathyroid hormone analog. Cov txheej txheem phais feem ntau los kho tus mob no yog vertebroplasty thiab kyphoplasty.
Dab tsi zoo sib xws ntawm Osteogenesis Imperfecta thiab Osteoporosis?
- Osteogenesis imperfecta thiab osteoporosis yog ob yam kab mob sib txawv ntawm pob txha.
- Ob qho kev kho mob tuaj yeem tshwm sim txij thaum yau nws tus kheej.
- Lawv tuaj yeem tshwm sim vim muaj kev hloov pauv ntawm noob caj noob ces.
- Ob qho kev kho mob tuaj yeem ua rau pob txha pob txha.
- Lawv yog cov mob kho tau.
Qhov txawv ntawm Osteogenesis Imperfecta thiab Osteoporosis yog dab tsi?
Osteogenesis imperfecta yog ib hom kab mob caj ces uas ua rau cov pob txha txawv txav, thaum osteoporosis yog ib yam kab mob uas ua rau cov pob txha tsis zoo. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm osteogenesis imperfecta thiab osteoporosis. Tsis tas li ntawd, osteogenesis imperfecta cuam tshuam rau txiv neej thiab poj niam sib npaug, thaum osteoporosis cuam tshuam rau poj niam ntau dua li txiv neej.
Cov hauv qab no qhia txog qhov sib txawv ntawm osteogenesis imperfecta thiab osteoporosis hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Osteogenesis Imperfecta vs Osteoporosis
Osteogenesis imperfecta thiab osteoporosis yog ob hom kab mob sib txawv. Ob qho kev kho mob no tuaj yeem yog vim muaj kev hloov pauv ntawm cov noob caj noob ces. Osteogenesis imperfecta yog ib hom kab mob caj ces uas ua rau cov pob txha txawv txav, thaum osteoporosis yog ib yam kab mob caj ces uas ua rau poob pob txha. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm osteogenesis imperfecta thiab osteoporosis.
