Qhov sib txawv tseem ceeb ntawm kev hloov pauv ntawm intragenic thiab extragenic suppressor mutation yog qhov intragenic suppressor mutation yog ib qho kev hloov pauv uas tshwm sim hauv tib lub noob. Hauv qhov sib piv, qhov kev hloov pauv ntawm extragenic suppressor yog kev hloov pauv uas tshwm sim hauv cov noob sib txawv.
Kev hloov pauv yog kev hloov pauv ntawm nucleotide ib ntu ntawm cov noob. Kev tawm tsam kev hloov pauv yog qhov hloov pauv thib ob uas cuam tshuam cov nyhuv phenotypic ntawm thawj qhov kev hloov pauv. Kev txwv kev hloov pauv tshwm sim ntawm qhov chaw sib txawv ntawm thawj qhov kev hloov pauv. Nws tuaj yeem rov ua haujlwm qub ntawm cov noob hloov pauv. Muaj ob hom kev txwv kev hloov pauv. Lawv yog intragenic suppression mutation thiab intergenic (extragenic) suppression mutations.
Dab tsi yog Intragenic Suppressor Mutation?
Intragenic suppressor mutation yog ib qho ntawm ob hom kev hloov pauv hloov. Raws li lub npe qhia, tus suppressor nyob rau hauv tib lub noob ntawm thawj kev hloov. Yog li ntawd, qhov kev hloov pauv thib ob tshwm sim nyob rau hauv tib lub noob kom txo qis lossis thim rov qab qhov kev hloov pauv qub ntawm cov nyhuv phenotypic.
Daim duab 01: Kev Tiv Thaiv Kev Hloov Pauv
Muaj ntau lub tswv yim los ntawm qhov kev hloov pauv ntawm intragenic suppressor hloov chaw. Lawv suav nrog tib lub chaw hloov pauv, kev hloov pauv hloov pauv, hloov pauv hauv kev sib txuas, thiab thim rov qab ntawm kev hloov pauv tseem ceeb los ntawm cis-knockout. Hauv feem ntau intragenic suppressor mutations, qhov kev hloov pauv tshwm sim nyob rau hauv ib qho sib txawv nucleotide nyob rau hauv tib triplet nyob rau hauv ib txoj kev uas lub codon encodes tus thawj amino acid.
Dab tsi yog Extragenic Suppressor Mutation?
Extragenic suppressor mutation lossis intergenic suppressor mutation yog hom thib ob ntawm kev hloov pauv hloov. Nyob rau hauv hom kev hloov no, tus suppressor nyob rau hauv ib tug txawv gene piv rau cov noob ntawm thawj kev hloov. Extragenic suppression mutation tuaj yeem tshwm sim nyob rau hauv ntau txoj hauv kev xws li kev hloov pauv hauv kev sib txuas, kev txhais lus lossis tsis muaj tseeb-kho kom zoo. Ntxiv mus, lawv tuaj yeem tshwm sim los ntawm kev hla dhau, kev siv tshuaj ntau npaum li cas, kev cuam tshuam ntawm cov khoom lag luam, lossis tshem tawm cov khoom lom. Feem ntau extragenic suppressor mutations ua rau ib yam khoom uas tuaj yeem them rau qhov tsis ua haujlwm hauv thawj qhov kev hloov pauv. Extragenic suppressor mutations yog qhov tseem ceeb hauv kev txheeb xyuas thiab kawm kev cuam tshuam ntawm cov molecules zoo li cov proteins.
Dab tsi yog qhov zoo sib xws ntawm Intragenic thiab Extragenic Suppressor Mutation?
- Intragenic thiab extragenic suppressor mutations yog ob hom kev txwv kev hloov pauv.
- Lawv yog qhov hloov pauv thib ob uas tshwm sim ntawm qhov chaw sib txawv ntawm qhov chaw ntawm thawj qhov kev hloov pauv.
- Ob hom kev hloov pauv cuam tshuam cov txiaj ntsig phenotypic ntawm thawj qhov kev hloov pauv.
- Hauv lwm lo lus, ob hom kev hloov pauv muaj peev xwm rov qab tau cov phenotype pom ua ntej kev hloov pauv keeb kwm yav dhau los.
Qhov txawv ntawm Intragenic thiab Extragenic Suppressor Mutation yog dab tsi?
Suppressor mutation yog kev hloov pauv thib ob uas rov ua haujlwm ntawm cov noob ploj los ntawm kev hloov pauv thawj zaug. Ib qho kev hloov pauv uas tshwm sim hauv tib lub noob yog hu ua intragenic suppressor mutation thaum muaj kev hloov pauv uas tshwm sim hauv cov noob sib txawv hu ua extragenic suppressor mutation. Yog li, qhov no yog qhov sib txawv ntawm qhov sib txawv ntawm intragenic thiab extragenic suppressor mutation.
Hauv qab no yog cov ntsiab lus ntawm qhov sib txawv ntawm intragenic thiab extragenic suppressor mutation hauv daim ntawv tabular.
Summary – Intragenic vs Extragenic Suppressor Mutation
Kev txwv tsis pub hloov pauv yog qhov hloov pauv thib ob uas kho cov haujlwm qub ntawm cov noob hloov pauv. Intragenic suppressor mutation tshwm sim nyob rau hauv tib lub noob uas qhov kev hloov pauv qub tau tshwm sim thiab kho cov tsiaj qus phenotype. Extragenic suppressor mutation tshwm sim nyob rau hauv ib lub noob sib txawv thiab kho cov nyhuv phenotypic ntawm thawj kev hloov pauv. Yog li, qhov no yog qhov sib txawv ntawm qhov sib txawv ntawm intragenic thiab extragenic suppressor mutation.
