Qhov sib txawv tseem ceeb ntawm kev tawm tsam thiab cov corepressor yog cov protein repressor ncaj qha khi rau tus neeg teb xov tooj ntawm cov noob thiab inhibits gene qhia thaum corepressor protein khi rau cov protein repressor thiab indirectly tswj cov noob qhia.
Genes yog cov chav nyob ntawm caj ces. Lawv muaj cov ntaub ntawv caj ces los ua cov protein. Txhawm rau ua kom cov protein, cov noob yuav tsum tau hais los ntawm kev sau thiab txhais lus. Cov kev hloov pauv yuav tsum khi rau cov neeg txhawb nqa thiab txhawb nqa thiab nrhiav RNA polymerase enzyme los pib sau ntawv. Gene qhia tuaj yeem tswj tau tshwj xeeb tshaj yog nyob rau theem kev hloov pauv. Tus repressor yog ib qho protein uas inhibits gene qhia. Corepressor yog ib qho protein uas tsis ncaj qha tswj cov noob qhia los ntawm kev khi rau cov khoom hloov pauv. Repressors nrhiav corepressor complexes. Hauv eukaryotes, ob qho tib si repressors thiab corepressors yog cov proteins.
Tus neeg ntxeev siab yog dab tsi?
Repressor yog cov protein uas khi rau DNA lossis RNA thiab inhibits qhov kev qhia ntawm ib lossis ntau cov noob. Feem ntau cov repressor proteins khi nrog rau cheeb tsam txhawb los yog cuam tshuam silencers. DNA binding repressor proteins tiv thaiv kev khi ntawm RNA polymerase rau kev txhawb nqa qib ntawm cov noob thiab nres qhov kev hloov pauv ntawm cov noob mus rau hauv mRNA.
Daim duab 01: Tus neeg ntxeev siab
(1: RNA Polymerase, 2: Repressor, 3: Promoter, 4: Operator, 5: Lactose, 6: lacZ, 7: lacY, 8: lacA.)
RNA binding repressor proteins, ntawm qhov tod tes, thaiv kev txhais ntawm mRNA rau hauv cov protein. Methionine repressor (MetJ) yog ib qho piv txwv ntawm repressor protein. Lactose repressor protein (LacI), uas tswj cov kev qhia ntawm lactose metabolic noob, kuj yog ib qho piv txwv ntawm repressor protein.
Corepressor yog dab tsi?
Corepressor yog cov protein uas khi rau cov protein repressor thiab tsis ncaj qha tswj cov noob qhia. Nws yog ib qho effector molecule. Lawv muaj peev xwm mus qhib repressors. Kev nrhiav cov corepressor yog ua los ntawm cov protein repressor vim lawv tsis muaj peev xwm los khi nrog DNA ntawm nws tus kheej. Corepressors sib tw nrog cov coactivators rau tib qhov chaw sib khi thiab khi rau cov khoom siv hloov pauv kom thiaj li txwv tsis pub cov noob qhia. Hauv prokaryotes, corepressors yog cov khoom me me. Hauv tib neeg, muaj ob peb lub kaum rau ntau pua tus corepressors. Feem ntau, cov corepressors muaj xws li corepressor complexes muaj ntau yam proteins.
Dab tsi yog qhov Zoo sib xws ntawm Kev Ruaj Ntseg thiab Corepressor?
- Nyob rau hauv eukaryotes, repressors thiab corepressors yog cov proteins uas tswj cov noob qhia.
- Repressors nrhiav corepressor complexes.
- Corepressor qhib qhov kev tawm tsam los ntawm kev khi nrog nws.
Qhov txawv ntawm Repressor thiab Corepressor yog dab tsi?
Ob tus neeg tawm tsam thiab corepressor tswj cov noob qhia los ntawm inhibiting nws. Repressor khi rau daim DNA hu ua cov neeg ua haujlwm hauv cov noob thaum corepressor khi rau tus neeg ntxeev siab. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm kev tawm tsam thiab corepressor. Repressor thaiv qhov txuas ntawm RNA polymerase rau tus txhawb nqa thaum corepressor sib tw nrog cov coactivators los khi cov ntsiab lus hloov pauv. Ntxiv mus, cov neeg tawm tsam khi rau cov noob tus neeg teb xov tooj DNA ib ntus thaum cov corepressors tsis ncaj qha khi rau DNA.
Cov infographic hauv qab no qhia txog qhov sib txawv ntawm kev tawm tsam thiab corepressor hauv daim ntawv teev npe.
Summary – Repressor vs Corepressor
Ob tus neeg tawm tsam thiab corepressor thaiv cov noob qhia. Corepressors khi nrog cov neeg tawm tsam thiab qhib lawv txhawm rau txhawm rau thaiv cov noob caj noob ces. Repressor khi nrog tus neeg teb xov tooj ua ntu zus ntawm cov noob thiab thaiv kev khi ntawm RNA polymerase enzyme rau tus txhawb nqa. Thaum RNA polymerase tsis khi rau tus txhawb nqa ntawm cov noob, kev hloov pauv tsis tau pib. Thaum kawg, gene qhia yog inhibited. Yog li, qhov no qhia txog qhov sib txawv ntawm tus neeg ntxeev siab thiab corepressor.
