Qhov sib txawv tseem ceeb ntawm linear thiab rotary molecular motors yog nyob ntawm lub hauv paus ntawm kev txav ntawm cov complexes uas tsim lub cev muaj zog protein. Thaum linear molecular motors qhia unidirectional linear motion ntawm complexes, rotary molecular motors qhia rotatory txav nyob ib ncig ntawm cov complexes tsim lub molecular motor.
Molecular motors yog ib qho tseem ceeb biomolecules uas koom nrog ntau yam kev cuam tshuam, tshwj xeeb tshaj yog txuam nrog lub zog tsim nyob rau hauv cov nqe lus ntawm adenosine triphosphate (ATP). Lawv ua lub luag haujlwm tseem ceeb hauv kev txav los yog kev ua haujlwm kho tshuab. Lub cev muaj zog cov proteins siv lub zog dawb los ntawm ATP lossis nucleotide triphosphate hydrolysis thiaj li tsim tau lub zog siv tshuab. Muaj ob hom molecular motors li linear molecular motors thiab rotary molecular motors. Lawv sawv cev rau ob hom kev ua haujlwm ntawm lub cev muaj zog.
Dab tsi yog Linear Molecular Motors?
Linear molecular motors ua lub luag haujlwm tseem ceeb hauv kev txav thiab kev ua haujlwm ntawm lub cev. Lawv kuj hu ua cytoskeletal motor proteins. Linear molecular motors tsiv mus nyob rau hauv ib tug unidirectional yam raws li cov protein complexes uas tsim lub molecular motor. Cov kab hluav taws xob molecular no muaj peev xwm siv tshuaj lom neeg lub zog hauv daim ntawv ntawm ATP hydrolysis, uas tso cai rau lawv txav mus rau hauv txoj kab khiav. Muaj cov tshuaj tiv thaiv sib txuas uas feem ntau tshwm sim nrog cov kab hluav taws xob molecular hauv cov ntsiab lus ntawm ATP hydrolysis thiab kev txav chaw.
Daim duab 01: Actin thiab Myosin Molecules
Muaj ob lub ntsiab linear molecular motors. Lawv yog actin motors thiab microtubule motors. Cov actin motors suav nrog myosins thaum lub microtubule motors suav nrog kinesins thiab dyneins. Myosins belongs rau superfamily ntawm actin motor proteins. Lawv koom nrog hauv kev hloov tshuaj lom neeg rau lub zog siv tshuab, yog li tsim kom muaj zog thiab txav mus los. Kinesins yog ib hom microtubule motors uas feem ntau koom nrog hauv kev tsim spindle thaum mitosis thiab meiosis. Lawv yog ib qho tseem ceeb rau kev tsim spindle hauv mitotic thiab meiotic chromosome sib cais thaum lub sij hawm ntawm tes. Nyob rau hauv sib piv, dyneins yog ntau complex motor molecules uas koom nyob rau hauv intracellular thauj mechanisms.
Rotary Molecular Motors yog dab tsi?
Rotary molecular motors feem ntau koom nrog lub zog tsim los ntawm ATP synthase complex thiab pab txhawb kev sib hloov ntawm cov khoom ntawm cov complex. Cov piv txwv classic ntawm lub cev muaj zog molecular sawv cev rau F0–F1 ATP synthase tsev neeg ntawm cov proteins. Lub cim ntawm ATP yog nyob ntawm cov proton gradient uas muaj nyob thoob plaws hauv daim nyias nyias. Qhov no catalyzes kev sib hloov ntawm tus kheej subunits ntawm lub cev muaj zog molecule complex uas ua rau ATP tiam.
Daim duab 02: F0 – F1 ATP Synthase
Tsis tas li ntawd, lub tshuab hluav taws xob rotary kuj tseem muaj nyob hauv cov kab mob flagellum qauv. Nws tsim lub hauv paus phaj thiab tswj cov kab mob flagellar txav los ntawm lub tshuab teb molecular.
Dab tsi yog qhov zoo sib xws ntawm Linear thiab Rotary Molecular Motors?
- Kab thiab teb motors yog ob hom molecular motors.
- Cov molecular motors muaj nyob rau hauv ob qho tib si eukaryotic thiab prokaryotic hlwb.
- Ob leeg yog cov qauv ntawm cov protein subunits tsim cov complexes hu ua motors.
- Nyob hauv ob hom motors, kev sib txuas ntawm cov subunits plays lub luag haujlwm tseem ceeb hauv nws txoj haujlwm.
- Lawv yog cov active molecules.
- Ob leeg siv lub zog hauv daim ntawv ntawm ATP hydrolysis lossis proton motive force.
- Lawv pab txhawb kev txav mus los.
- Ob leeg yog qhov tseem ceeb hauv txoj hauv kev biochemical ntawm cov hlwb.
- Ntxiv mus, lawv tseem ceeb hauv kev thauj mus los.
Qhov txawv ntawm Kab thiab Rotary Molecular Motors yog dab tsi?
Qhov sib txawv tseem ceeb ntawm linear thiab rotary molecular motors yog hom kev txav uas lawv qhia. Thaum linear molecular motors pab txhawb unidirectional linear txav tom qab ATP hydrolysis, rotary molecular motors pab txhawb kev sib hloov tom qab ATP hydrolysis. Actin molecular motors thiab microtubule molecule motors yog ob qho piv txwv ntawm linear molecular motors thaum ATP synthase motors thiab flagellar motor proteins yog rotary molecular motors.
Cov lus qhia hauv qab no qhia txog qhov sib txawv ntawm cov kab thiab cov tshuab molecular.
Summary – Linear vs Rotary Molecular Motors
Molecular motors ua lub luag haujlwm tseem ceeb hauv kev kho cov kab mob biochemical hauv ob qho tib si prokaryotes thiab eukaryotes. Muaj ob lub ntsiab ntawm molecular motors li linear molecular motors thiab rotary molecular motors. Raws li nws lub npe implies, linear molecular motors pab txhawb linear zog nyob rau hauv nruab nrab ntawm ib tug neeg subunits ntawm complex motor protein, uas ua rau linear unidirectional suab. Raws li kev tawm tsam rau cov qauv ntawm cov motors molecular, cov motors teb ua rau kev sib hloov ntawm cov subunits, ua rau lub cev muaj zog protein complex. Qhov sib txawv ntawm kev txav yog li tau txais los ntawm ob hom motors pab txhawb ntau yam haujlwm hauv ob qho tib si prokaryotes thiab eukaryotes. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm linear thiab rotary molecular motors.
