Qhov sib txawv tseem ceeb ntawm hydride thiab methyl hloov yog qhov hloov pauv hydride tuaj yeem tshwm sim thaum lub atom hydrogen txav mus rau cov pa roj carbon atom uas coj tus nqi zoo los ntawm cov pa roj carbon uas nyob ib sab hauv tib lub molecule, qhov kev hloov methyl tshwm sim thaum pawg methyl. txav mus rau cov pa roj carbon atom uas coj tus nqi zoo los ntawm cov pa roj carbon atom uas nyob ib sab hauv tib lub molecule.
Cov ntsiab lus hydride hloov thiab methyl hloov pauv tuaj nyob rau hauv subtopic ntawm carbocation rearrangements. Ntawm no, ob qho tib si hydrogen atom lossis ib pawg methyl txav mus rau cov pa roj carbon atom los ntawm cov pa roj carbon atom uas nyob ib sab hauv tib lub compound.
Hydride Shift yog dab tsi?
Hydride hloov yog qhov txav ntawm hydrogen atom los ntawm ib cov pa roj carbon monoxide mus rau cov roj carbon atom uas nyob ib sab ntawm tib lub ntsiab lus. Feem ntau, cov carbocation rearrangements tshwm sim nyob rau hauv theem nrab carbocations. Cov carbocation rearranged yog cov khoom loj ntawm cov tshuaj tiv thaiv synthesis vim nws yog daim ntawv ruaj khov tshaj plaws.
Yog hais tias qhov thib ob carbocation yog vicinal mus rau tertiary carbon atom bearing hydrogen atom, ces hydride hloov tshwm sim. Peb hu qhov no 1, 2-hydride hloov. Qhov kev hloov pauv no tuaj yeem ua tau thaum muaj cov nqi zoo ntawm cov pa roj carbon atom qhov twg nws cov pa roj carbon atom uas nyob ib sab muaj cov hydrogen atom tshem tau.
Methyl Shift yog dab tsi?
Methyl hloov pauv yog qhov txav ntawm pawg methyl los ntawm ib lub atom carbon mus rau ib qho kev them nyiaj, uas nyob ib sab carbon atom ntawm tib lub compound. Peb hu qhov no ua methyl hloov yog tias cov tshuaj txav mus los yog pawg methyl, thiab nws tuaj yeem ua tau lwm pawg alkyl ib yam nkaus. Ntawm no, cov pab pawg me me alkyl zoo li yog cov tshuaj lom neeg txav uas txuas rau cov pa roj carbon atom. Kev hloov ntawm pawg methyl yog hu ua 1, 2-methyl shift.
Dab tsi zoo sib xws ntawm Hydride thiab Methyl Shift?
Feem ntau, cov txheej txheem rau hydride hloov thiab methyl hloov yog tib yam. Ntawm no, tus xub pib los ntawm cov pa roj carbon atom uas qhov hloov pauv (hydrogen atom ntawm pawg methyl) txuas rau thiab cov ntsiab lus ntawm cov roj carbon atom. Nws qhia tau hais tias hydrogen atom los yog pawg methyl tsiv mus rau carbocation nrog nws cov electrons. Ob qho kev hloov pauv no ua rau muaj qhov carbocation tshiab thaum kawg ntawm cov txheej txheem rearrangement. Ntxiv mus, hydride hloov lossis hloov methyl tsis tuaj yeem ua tiav rau 1, 3 lossis 1, 4 hloov.
Qhov txawv ntawm Hydride thiab Methyl Shift yog dab tsi?
Hydride hloov thiab methyl hloov yog hom carbocation rearrangements. Qhov sib txawv tseem ceeb ntawm hydride thiab methyl hloov pauv yog tias kev hloov pauv hydride tuaj yeem tshwm sim thaum lub atom hydrogen txav mus rau cov pa roj carbon atom coj tus nqi zoo los ntawm cov pa roj carbon uas nyob ib sab hauv tib lub molecule, whereas methyl hloov tshwm sim thaum ib pawg methyl txav mus rau carbon atom. coj tus nqi zoo los ntawm cov pa roj carbon atom uas nyob ib sab hauv tib lub molecule. Tsis tas li ntawd, thaum lub hydride hloov yog lub npe hu ua 1, 2-hydride hloov, methyl hloov yog lub npe hu ua 1, 2-methyl hloov.
Hauv qab infographic qhia txog qhov sib txawv ntawm hydride thiab methyl hloov.
Summary – Hydride vs Methyl Shift
Hydride hloov thiab methyl hloov yog hom carbocation rearrangements. Qhov sib txawv tseem ceeb ntawm hydride thiab methyl hloov pauv yog tias kev hloov pauv hydride tuaj yeem tshwm sim thaum hydrogen atom txav mus rau cov pa roj carbon atom coj tus nqi zoo los ntawm cov pa roj carbon uas nyob ib sab hauv tib lub molecule whereas methyl hloov tshwm sim thaum pawg methyl txav mus rau cov pa roj carbon atom bearing. ib tug zoo nqi los ntawm ib tug nyob ib sab carbon atom nyob rau hauv tib molecule.
