Qhov sib txawv tseem ceeb ntawm alloantibody thiab autoantibody yog qhov alloantibody yog cov tshuaj tiv thaiv uas tsim tawm tsam alloantigens, uas yog txawv teb chaws antigens qhia los ntawm kev tso ntshav lossis cev xeeb tub. Lub caij no, autoantibody yog ib qho tshuaj tiv thaiv uas ua rau nws tus kheej-antigens.
Cov tshuaj tiv thaiv yog tsim los ntawm kev tiv thaiv kab mob. Lawv tuaj yeem cuam tshuam qhov muaj, qhov xwm txheej thiab kev siv zog ntawm kev tiv thaiv kab mob. Lub cev tiv thaiv kab mob yuav tsum muaj peev xwm txheeb xyuas tus kheej-antigens thiab txawv teb chaws antigens cais. Nws yog qhov tseem ceeb rau nws txoj haujlwm. B hlwb ntawm lub cev tiv thaiv kab mob tsim cov tshuaj tiv thaiv antigens. Alloantibodies thiab autoantibodies yog ob hom tshuaj tiv thaiv. Alloantibodies yog tsim los ntawm kev qhia txog alloantigens rau hauv lub cev los ntawm kev tso ntshav lossis cev xeeb tub. Hauv qhov sib piv, autoantibodies yog cov tshuaj tiv thaiv kab mob uas cuam tshuam nrog tus kheej-antigens. Cov tshuaj tiv thaiv ntawm autoantibodies nrog nws tus kheej-antigens yog lub luag haujlwm rau o, kev puas tsuaj thiab ua haujlwm tsis zoo ntawm cov ntaub so ntswg thiab cov kabmob, ua rau cov tsos mob thiab cov tsos mob ntawm cov kab mob autoimmune.
Dab tsi yog Alloantibody?
Alloantibody yog ib qho tshuaj tiv thaiv uas tsim tawm tsam alloantigens uas nkag mus rau hauv lub cev los ntawm kev tso ntshav lossis cev xeeb tub. Alloantigens tsis yog cov khoom ntawm lub cev nws tus kheej. Lawv raug tsim nyob rau hauv kev ncig. Ntxiv mus, alloantigens txawv ntawm cov tib neeg ntawm tib hom los ntawm cov amino acid sequences.
Daim duab 01: Cov qauv ntawm cov tshuaj tiv thaiv kab mob
Alloantigens yog cov proteins lossis lwm yam tshuaj, xws li histocompatibility lossis ntshav liab antigens muaj nyob hauv cov tswv cuab ntawm tib hom. Cov alloantigens no muaj peev xwm inducing zus tau tej cov alloantibodies nyob rau hauv lwm cov tswv cuab ntawm tib hom. Qee cov tshuaj tiv thaiv kab mob ua rau muaj kev phom sij rau cov neeg mob los ntawm kev rhuav tshem cov qe ntshav liab lossis ua mob rau tus menyuam hauv plab thaum leej niam nqa ib qho alloantibody tawm tsam antigen ntawm tus menyuam cov qe ntshav liab.
Dab tsi yog Autoantibody?
Ib autoantibody yog ib qho tshuaj tiv thaiv uas ua haujlwm tawm tsam tus neeg lub cev antigens. Hauv lwm lo lus, autoantibodies yog cov tshuaj tiv thaiv uas tawm tsam tus kheej-antigens. Yog li, lawv yog cov tshuaj tiv thaiv kab mob uas tsis tuaj yeem sib txawv ntawm tus kheej thiab tsis yog tus kheej antigens. Cov tshuaj tiv thaiv no yuam kev thiab ua rau tib neeg lub cev nqaij daim tawv lossis lub cev. Yog li, cov autoantibodies no yog lub luag haujlwm rau ntau yam kab mob autoimmune. Lawv muaj txiaj ntsig zoo li biomarkers ntawm cov kab mob. Autoantibodies feem ntau pom hauv cov tib neeg noj qab haus huv.
Ib txwm peb lub cev tiv thaiv kab mob kev tswj hwm tus kheej ua rau nruab nrab thiab tshem tawm autoantibodies ua ntej lawv loj tuaj. Tab sis thaum nws tsis ua rau nruab nrab, cov autoantibodies no puas hlwb, cov ntaub so ntswg thiab cov kabmob. Autoantibodies rhuav tshem peb cov hlwb los ntawm phagocytosis lossis cell lysis. Antinuclear antibodies, antineutrophil cytoplasmic antibodies, anti-ob-stranded DNA, anticentromere antibodies, anti-histone antibodies, thiab rheumatoid factor yog ob peb hom autoantibodies.
Dab tsi zoo sib xws ntawm Alloantibody thiab Autoantibody?
- Alloantibody thiab autoantibody yog ob hom tshuaj tiv thaiv uas tsim los ua cov lus teb rau kev tiv thaiv kab mob.
- Lawv yog cov proteins.
- Ntxiv mus, lawv khi nrog lawv cov antigens tshwj xeeb.
Qhov txawv ntawm Alloantibody thiab Autoantibody yog dab tsi?
Alloantibodies yog cov tshuaj tiv thaiv uas ua haujlwm tawm tsam alloantigens nkag rau hauv lub cev los ntawm kev tso ntshav lossis cev xeeb tub. Hauv qhov sib piv, autoantibodies yog cov tshuaj tiv thaiv kab mob uas cuam tshuam nrog cov khoom ntawm lub cev cov ntaub so ntswg thiab cov kabmob. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm alloantibody thiab autoantibody.
Ntxiv mus, lwm qhov sib txawv ntawm alloantibody thiab autoantibody yog tias cov alloantibodies khi nrog alloantigens thiab rhuav tshem lawv. Tab sis, cov autoantibodies khi nrog tus kheej-antigens thiab ua rau tib neeg lub cev nqaij daim tawv thiab lub cev puas tsuaj.
Summary – Alloantibody vs Autoantibody
Alloantibody thiab autoantibody yog ob hom tshuaj tiv thaiv uas tsim tawm hauv peb lub cev tawm tsam antigens. Alloantibody yog tsim tawm tsam alloantigens, uas yog txawv teb chaws antigens nkag rau hauv peb lub cev los ntawm kev tso ntshav los yog cev xeeb tub, thaum autoantibody yog ib qho tshuaj tiv thaiv uas ua rau nws tus kheej-antigens. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm alloantibody thiab autoantibody. Autoantibodies tsis tuaj yeem cais tus kheej-antigens thiab non-self antigens thaum alloantibodies tuaj yeem paub txog alloantigens thiab tsuas yog khi nrog alloantigens uas yog txawv teb chaws antigens nyob rau hauv lwm cov tswv cuab ntawm tib hom.
