Qhov Tseem Ceeb Qhov txawv - Megakaryocyte vs Platelet
Cov txheej txheem ntawm cov ntshav txhaws lossis thrombosis yog kho los ntawm platelets hauv cov ntshav. Cov txheej txheem ntshav txhaws yog qhov tseem ceeb txhawm rau tiv thaiv cov ntshav los ntawm lub cev thaum muaj kev raug mob sab nraud lossis kev raug mob sab hauv. Yog li, nws yog ib qho tseem ceeb kom tswj xyuas cov ntshav platelets hauv cov ntshav. Nws yog ib qho tseem ceeb kom rov ua kom cov platelet suav tam sim ntawd thaum muaj xwm txheej uas platelet suav txo. Megakaryocyte yog lub precursor ntawm platelet hlwb, thiab nws muaj ntau yam kev hloov hauv lub cev ua ntej tso tawm raws li ib tug platelet rau hauv cov hlab ntsha. Platelets yog ib hom ntawm cov qe ntshav, uas yuav tsum tau muaj nyob rau hauv cov txheej txheem ntawm cov ntshav txhaws. Qhov no yog qhov sib txawv tseem ceeb ntawm megakaryocyte thiab platelet.
Megakaryocyte yog dab tsi?
Megakaryocytes yog nucleated, myeloid hlwb uas feem ntau pom nyob rau hauv cov pob txha pob txha, ntsws thiab cov ntshav peripheral. Megakaryocytes muaj compact tab sis lobed nuclei thiab ib tug nyias ntug ntawm basophilic cytoplasm thiab muaj txog li 20 μm nyob rau hauv loj. Kev loj hlob ntawm megakaryocytes tshwm sim nyob rau hauv ib tug txheej txheem hu ua megakaryopoiesis uas tshwm sim nyob rau hauv lub fetal theem ntawm ib tug kab mob. Megakaryocytes tshwm sim los ntawm pluripotent hematopoietic qia hlwb thiab loj hlob mus rau hauv ob lub ntsiab precursor hlwb hu ua tawg tsim hlwb thiab cov colony tsim cov hlwb. Tom qab ntawd, megakaryocyte tau dhau los ua ntau qhov kev xav hauv nruab nrab los hloov nws cov cytoplasm thiab nws cov txheej txheem membrane txhawm rau txhim kho mus rau hauv cov neeg laus platelet. Tawm ntawm ntau yam uas pab platelet tsim los ntawm megakaryocytes, thrombopoietin (TPO) yog thawj tswj kev koom tes. Thaum ua tiav kev loj hlob ntawm megakaryocyte, lub xovtooj ntawm tes tau zoo nrog tag nrho cov protein uas xav tau thiab lwm yam tshuab uas xav tau rau platelet biogenesis.
Daim duab 01: Platelet Production los ntawm Megakaryocyte
Megakaryocytes tsim cov txuas ntxiv uas koom nrog hauv cov txheej txheem tso cov platelets rau cov ntshav. Cov protoplatelet txuas ntxiv no tau dhau los ua lwm yam kev cuam tshuam los tso cov platelet paub tab rau cov ntshav.
Platelet yog dab tsi?
Platelet yog cov kab mob sib kis ntawm cov pob txha pob txha uas suav txog ze li 20% ntawm tag nrho cov qe ntshav. Nws txoj kab uas hla nyob nruab nrab ntawm 3 mus rau 4 μm. Qhov nruab nrab platelet suav yog nyob nruab nrab ntawm 150,000 txog 450,000 platelets ib microliter ntawm cov ntshav. Lub luag haujlwm tseem ceeb ntawm platelets yog los pab txhawb cov txheej txheem ntawm cov ntshav txhaws los ntawm kev tsim cov platelet plugs hauv thawj theem ntawm cov ntshav txhaws. Platelets kuj tsim cov platelet factor 3 uas yog ib qho tseem ceeb hauv cov txheej txheem tshuaj tiv thaiv ntawm coagulation. Thaum qhov kev ncaj ncees ntawm cov hlab ntsha raug cuam tshuam los ntawm kev raug mob, circulating platelets thiab lwm yam ua ke nyob ze ntawm qhov chaw raug mob. Prostaglandins xws li thromboxane pab cov txheej txheem ntawm platelet aggregation thiab qhov no yog ua raws li los ntawm kev tsim cov fibrin network ntawm qhov chaw ntawm kev raug mob los tiv thaiv kev poob ntshav ntxiv.
Cov kab mob platelets tuaj yeem ua rau ntau qhov tsis sib xws hauv lub cev. Qee cov tshuaj noj qab haus huv xws li tshuaj aspirin, uas yog cov tshuaj uas tsis yog tshuaj steroidal anti-inflammatory, yog siv los tiv thaiv cov ntshav txhaws los ntawm kev cuam tshuam cov kauj ruam tshwj xeeb ntawm platelet aggregation.
Daim duab 02: Platelet
Cov kev tsis zoo ntawm cov ntshav platelet tseem tab tom tshawb fawb hauv cov xwm txheej zoo li thrombocytopenia uas txo cov ntshav platelet ntau heev. Thrombocytopenia kuj tseem tuaj yeem tshwm sim los ntawm qee yam kab mob xws li Dengue, qhov twg tus kab mob no muaj peev xwm ua kom cov platelets puas tsuaj ua rau cov qib platelet txo qis sai.
Dab tsi yog qhov zoo sib xws ntawm Megakaryocyte thiab Platelet?
- Qhov kawg ua haujlwm ntawm megakaryocytes thiab platelets yog pib txheej txheem ntshav txhaws.
- Organelle thiab glycoprotein subcellular faib yog zoo sib xws hauv ob hom cell.
- Qhov chaw tsim khoom ntawm ob lub hlwb yog pob txha pob txha.
Qhov txawv ntawm Megakaryocyte thiab Platelet yog dab tsi?
Megakaryocyte vs Platelet |
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| Megakaryocyte yog ib qho ua ntej ntawm cov cell cell uas tau muab los ntawm Hematopoietic qia cell. | Platelet yog ib hom ntawm cov qe ntshav koom nrog hauv cov txheej txheem txhaws. |
| Loj ntawm megakaryocytes yog nyob ib ncig ntawm 20 µm. | Loj ntawm cov platelet nyob ib ncig ntawm 4-5 µm. |
| qauv | |
| Megakaryocytes yog ncig lossis ovoid zoo li. | Platelets yog disk zoo li lub hlwb flattened. |
| Nyob ntawm Nucleus | |
| Ib lub nucleus muaj nyob hauv megakaryocytes. | Ib lub nucleus tsis nyob hauv platelets. |
| Lub luag haujlwm tseem ceeb | |
| Lub luag haujlwm tseem ceeb ntawm megakaryocyte yog tsim cov platelets thiab ua raws li platelet precursors | ntshav txhaws thiab pib cov txheej txheem coagulation yog lub luag haujlwm tseem ceeb ntawm platelets. |
| suav ib mm3 | |
| Megakaryocytes suav tsis tau teev tseg. | Platelet suav nyob nruab nrab ntawm 150,000 txog 450,000 platelets ib µl. |
Summary – Megakaryocyte vs Platelet
ntshav txhaws yog txheej txheem nyuaj uas muaj ntau hom hlwb. Megakaryocyte yog lub precursor ntawm platelet hlwb, thiab nws muaj ntau yam kev hloov hauv lub cev ua ntej tso tawm raws li ib tug platelet rau hauv cov hlab ntsha. Platelets yog ib hom ntawm cov qe ntshav, uas yuav tsum tau muaj nyob rau hauv cov txheej txheem ntawm cov ntshav txhaws. Qhov no yog qhov txawv ntawm megakaryocyte thiab platelet. Cov txheej txheem ntawm kev hloov ntawm megakaryocyte theem mus rau cov platelet paub tab yog cov txheej txheem nyuaj uas muaj ntau yam. Txawm hais tias cov txheej txheem tseem ceeb ntawm cov txheej txheem platelet maturation tau piav qhia, cov txheej txheem kev cai tshwj xeeb tseem tsis tau nkag siab thiab xav tau kev tshawb fawb ntxiv.
Download PDF Version of Megakaryocyte vs Platelet
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