Key Difference – DHEA vs DHA
DHEA (Dehydroepiandrosterone) thiab DHA (Docosahexaenoic acid) yog cov khoom tseem ceeb hauv tib neeg lub cev. Ob lub tebchaw koom nrog hauv qhov sib txawv ntawm kev txhim kho thiab kev tswj hwm ntawm lub cev. Txawm hais tias ob qho tib si cov ntsiab lus no zoo li muaj cov ntsiab lus zoo sib xws, ob qho tib si sib txawv kiag li ntawm kev faib tawm, kev sib txuas, thiab kev ua haujlwm. DHEA yog ib qho endogenous steroid hormone, thiab DHA yog omega-3 fatty acid. Qhov no yog qhov txawv ntawm DHEA thiab DHA.
DHEA yog dab tsi?
DHEA (dehydroepiandrosterone) feem ntau hu ua androstenolone. DHEA yog ib qho endogenous steroid hormone. Nws yog tsim nyob rau hauv cov qog adrenal, hlwb thiab hauv gonads. DHEA suav hais tias muaj ntau lub peev xwm ua haujlwm hauv lub cev thiab yog ib qho ntawm cov tshuaj steroids uas nyob hauv lub cev ntau tshaj. Nyob rau hauv lub hlwb, DHEA ua raws li ib tug metabolic intermediate uas koom nyob rau hauv lub synthesis ntawm estrogen thiab androgen steroid poj niam txiv neej cov tshuaj hormones.
Nws kuj muaj peev xwm ua tau raws li cov neurosteroid thiab neutrophin uas DHEA khi rau ib qho array ntawm nuclear thiab cell nto proteins. Neurosteroids muaj lub peev xwm los koom nrog hauv kev hloov pauv sai ntawm cov txheej txheem neuronal excitability uas tau ua tiav los ntawm kev sib txawv nrog cov xov tooj ntawm tes receptors thiab ligand-gated ion channels. Neurotrophins yog ib chav kawm ntawm cov proteins uas koom nrog hauv induction ntawm ciaj sia taus thiab kev loj hlob ntawm neurons. Yog li ntawd, DHEA yog ib qho tseem ceeb ntawm lub hauv paus paj hlwb.
Lub synthesizing mechanism ntawm DHEA koom nrog ob cov tshuaj hormones ACTH (adrenocorticotropic hormone) thiab GnRH (gonadotrophin releasing hormone). ACTH tswj cov synthesis ntawm DHEA nyob rau hauv lub zona reticularis ntawm adrenal cortex thiab GnRH tswj gonads thaum lub sij hawm synthesis ntawm DHEA. Qhov no endogenous steroid hormone kuj tsim nyob rau hauv lub hlwb. Cov roj (cholesterol) ua haujlwm ua ntej hauv kev tsim DHEA los ntawm cov enzymes sib txawv. Tawm ntawm tag nrho DHEA synthesized hauv lub cev, feem pua ntawm DHEA ntau dua yog muab los ntawm adrenal cortex thiab los ntawm desulfation ntawm dehydroepiandrosterone sulfate (DHEAS).
Figure 01: DHEA
Ntau dua DHEA ntau lawm hauv lub cev tuaj yeem txhawb nqa los ntawm kev ua haujlwm tsis tu ncua. Hauv primates, qhov no ua tiav los ntawm kev txwv calorie. Cov kev xav qhia tias endogenous DHEA ntau lawm stimulation los ntawm kev txwv calories ua rau lub neej ntev.
YDHA yog dab tsi?
DHA (docosahexaenoic acid) yog suav tias yog omega-3 fatty acid uas yog tam sim no ua cov txheej txheem tseem ceeb hauv tib neeg lub hlwb, cerebral cortex, retina ntawm lub qhov muag thiab tawv nqaij. DHA tuaj yeem tau los ntawm ntau qhov chaw uas suav nrog niam mis, roj ntses lossis roj los ntawm qee hom algae.
Nws kuj tuaj yeem raug tsim los ntawm alpha-linolenic acid, uas yog ib qho ntawm ob qho tseem ceeb fatty acids uas tsis tuaj yeem ua rau hauv lub cev. Cov txheej txheem no yog siv feem ntau los ntawm herbivores thiab carnivores uas tsis nyob ntawm ib qho chaw noj nqaij nruab deg. Alpha-linolenic acid yog tsim nyob rau hauv cov nroj tsuag thiab yog luv luv omega-3 fatty acid. Tsiaj txhu uas tau txais cov nqaij nruab deg tsawg muaj peev xwm tsim DHA los ntawm txoj kev metabolic ntawm cov khoom qis.
Ntses thiab lwm yam kab mob sib kis tau txais DHA los ntawm cov kab mob photosynthetic microalgae uas yog heterotrophic uas yog tam sim no ua cov khoom noj hauv dej hiav txwv. Qhov concentration ntawm DHA nce raws cov khoom noj khoom haus hauv cov ecosystems. Crypthecodinium cohnii thiab Schizochytrium yog ntau hom microalgae uas koom nrog hauv kev tsim khoom ntawm DHA. Txij li thaum DHA yog synthesized siv cov nroj tsuag-raws li kev pab, nws yog 100% neeg tsis noj nqaij.
Figure 02: DHA
Nyob rau hauv cov ntsiab lus ntawm lub hlwb thiab retina ntawm lub qhov muag, DHA yog tam sim no raws li ntau tshaj omega-3 fatty acid. 60% ntawm lub hlwb tag nrho cov unsaturated fatty acids yog tam sim no raws li DHA thaum nyob rau hauv lub retina; nws yog 40%. Qhov zoo tshaj plaws ntawm DHA rau tib neeg thaum cev xeeb tub yog tau los ntawm niam mis los ntawm kev pub niam mis. Cov mis nyuj muaj feem ntau ntawm DHA piv rau lwm qhov chaw. Tom qab theem ntawm kev loj hlob ntawm tib neeg, DHA tau txais los ntawm kev noj haus.
DHEA thiab DHA yog dab tsi?
Ob leeg koom nrog kev txhim kho ntawm tib neeg lub cev
Qhov txawv ntawm DHEA thiab DHA yog dab tsi?
DHEA vs DHA |
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| DHEA yog ib qho endogenous steroid hormone. | YDHA yog ib qho omega-3 fatty acid. |
| Synthesis | |
| DHEA yog tsim los ntawm cov qog adrenal, hlwb thiab hauv cov gonads thiab muab los ntawm cov roj cholesterol. | DHA yog tsim los ntawm kev hloov kho Escherichia coli, alpha linolenic acid thiab los ntawm photosynthetic microalgae Crypthecodinium cohnii thiab Schizochytrium. |
| Function | |
| DHEA ua haujlwm ua ntej rau txiv neej thiab poj niam txiv neej cov tshuaj hormones, suav nrog testosterone thiab estrogen. | DHA yog ib qho tseem ceeb ntawm cov qauv thiab kev ua haujlwm ntawm lub hlwb tsim thiab tseem ceeb rau kev noj qab haus huv ntawm lub plawv. |
Summary – DHEA vs DHA
DHEA yog ib qho tshuaj steroid endogenous. Nws yog tsuas yog tsim nyob rau hauv cov qog adrenal, hlwb thiab hauv gonads. DHEA tam sim no yog ib qho tseem ceeb ntawm lub hauv paus paj hlwb uas ua haujlwm hauv kev loj hlob thiab kev zoo siab ntawm cov neurons. DHA yog omega-3 fatty acid. DHA yog tsim los ntawm kev hloov kho Escherichia coli, alpha-linolenic acid thiab los ntawm photosynthetic microalgae Crypthecodinium cohnii thiab Schizochytrium. Ob lub tebchaw koom nrog hauv qhov sib txawv ntawm kev txhim kho thiab kev tswj hwm ntawm lub cev. Qhov no yog qhov txawv ntawm DHEA thiab DHA.
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