Qhov txawv ntawm Theophylline thiab Aminophylline

2024 Tus sau: Alex Aldridge | [email protected]. Kawg hloov kho: 2023-12-17 13:40

Qhov sib txawv tseem ceeb ntawm theophylline thiab aminophylline yog qhov theophylline muaj zog thiab ua haujlwm ntev dua li aminophylline.

Ob qho tib si theophylline thiab aminophylline tseem ceeb ua tshuaj hauv kev siv tshuaj kho mob. Theophylline yog siv los ua tshuaj rau kev kho mob ntawm cov kab mob hauv lub ntsws. Aminophylline kuj yog ib qho kev kho mob rau kev ua pa ntawm txoj hlab ntsws los ntawm kev mob ntsws asthma.

Theophylline yog dab tsi?

Theophylline yog ib yam tshuaj uas peb siv los kho cov kab mob ua pa xws li COPD (chronic obstructive pulmonary disease) thiab hawb pob. Nws yog cov tshuaj methylxanthine uas muaj cov tshuaj npe 1, 3-dimethylxanthine vim nws muaj ob pawg methyl txuas nrog xanthine molecule. Vim li no, cov tshuaj no poob rau hauv qeb ntawm xanthine tsev neeg; Yog li, cov qauv zoo ib yam li caffeine thiab theobromine. Tsis tas li ntawd, qhov sib xyaw no pom muaj nyob hauv cov xwm txheej raws li cov tshuaj yej thiab cocoa.

Cov tshuaj formula ntawm cov compound yog C ₇ H _8N 4_{O 2} thaum molar mass yog 180.16 g / mol. Thaum xav txog kev siv tshuaj kho mob ntawm cov tshuaj no, nws yog ib qho tseem ceeb hauv kev so ntawm cov leeg nqaij bronchial, ua kom lub plawv dhia, hauv kev tiv thaiv kab mob, ua rau lub raum ntshav khiav, thiab lwm yam. Txawm li cas los xij, nws tuaj yeem ua rau muaj tshuaj lom yog tias peb tsis ua. saib xyuas qib theophylline hauv cov ntshav. Cov teebmeem muaj xws li xeev siab, raws plab, nce plawv dhia, lub plawv dhia tsis zoo, thiab lwm yam.

Aminophylline yog dab tsi?

Aminophylline yog ib yam tshuaj uas peb siv los kho mob hawb pob lossis COPD tab sis muaj txiaj ntsig qis dua theophylline. Cov tshuaj muaj bronchodilator theophylline thiab ethylenediamine hauv qhov sib piv 2: 1. Feem ntau, peb tuaj yeem pom qhov sib xyaw no hauv daim ntawv lub cev qhuav dej, thiab ethylenediamine txhim kho cov solubility ntawm cov tshuaj no. Txawm hais tias ob qho tib si theophylline thiab aminophylline tseem ceeb yog cov tshuaj rau kev kho mob COPD, aminophylline tsis muaj zog thiab ua haujlwm luv luv hauv lub luag haujlwm no.

Daim duab 02: Cov Qauv Tshuaj ntawm Aminophylline

Cov tshuaj formula ntawm cov compound yog C₁₆H₂₄N₁₀O 4 _{thaum molar mass yog 420.42 g / mol. Thaum txiav txim siab txog kev siv tshuaj kho mob, nws yog ib qho tseem ceeb hauv kev kho cov hlab ntsws los ntawm kev mob ntsws asthma, emphysema thiab mob ntsws ntev. Ntxiv mus, nws muaj txiaj ntsig zoo rau kev thim rov qab regadenoson, dipyridamole, tiv thaiv lub plawv dhia qeeb, thiab lwm yam. Txawm li cas los xij, qhov sib xyaw no tuaj yeem ua rau theophylline toxicity.}

Qhov txawv ntawm Theophylline thiab Aminophylline yog dab tsi?

Theophylline yog ib yam tshuaj uas peb siv los kho cov kab mob ua pa xws li COPD thiab hawb pob. Hauv qhov sib piv, aminophylline yog cov tshuaj uas peb siv los kho mob hawb pob lossis COPD, tab sis nws muaj txiaj ntsig qis dua li theophylline. Yog li, qhov sib txawv tseem ceeb ntawm theophylline thiab aminophylline yog qhov theophylline muaj zog thiab ua haujlwm ntev dua li aminophylline.

Ntxiv mus, cov tshuaj formula ntawm theophylline yog C₇H₈N₄O _2, thiab molar mass yog 180.16 g / mol. Tab sis rau aminophylline, cov tshuaj formula yog C₁₆H₂₄N₁₀O_{4.,thiab molar mass yog 420.42 g / mol. Thaum xav txog qhov solubility hauv dej, theophylline yog dej-soluble tsawg dua piv rau aminophylline. Lwm qhov sib txawv ntawm theophylline thiab aminophylline yog qhov kev tshem tawm ib nrab-lub neej ntawm theophylline tsawg dua li ntawm aminophylline.}

Summary – Theophylline vs Aminophylline

Theophylline yog ib yam tshuaj uas peb siv los kho cov kab mob ua pa xws li COPD thiab mob hawb pob, thaum aminophylline yog cov tshuaj uas peb siv los kho mob hawb pob lossis COPD, tab sis nws muaj txiaj ntsig qis dua theophylline. Yog li, qhov sib txawv tseem ceeb ntawm theophylline thiab aminophylline yog qhov theophylline muaj zog thiab ua haujlwm ntev dua li aminophylline.

Image Courtesy:

1. "Cylmin 100mg los ntawm Tsuruhara" Los ntawm Uploader; Vantey - Duab los ntawm Vantey (Public Domain) ntawm Commons Wikimedia

2. "Aminophylline" Los ntawm Benrr101 - 100% Kuv tus kheej ua haujlwm (Public Domain) ntawm Commons Wikimedia