Qhov sib txawv tseem ceeb ntawm Induced Fit thiab Xauv thiab Qhov Tseem Ceeb yog qhov induced haum txoj kev xav, kev khi ntawm lub substrate nrog lub active site ntawm lub enzyme induces kev hloov kho ntawm cov duab ntawm lub active site mus rau hauv lub complementary duab ntawm lub enzyme. substrate. Whereas, nyob rau hauv lub xauv thiab qhov tseem ceeb txoj kev xav, lub substrate thiab lub active site ntawm lub enzyme yog complementary nyob rau hauv cov duab thaum pib.
Enzymes yog cov catalysts ntawm cov tshuaj tiv thaiv metabolic. Yog li ntawd, lawv yog tshwj xeeb rau lawv cov substrates. Lub substrate khi nrog qhov chaw nquag ntawm cov enzyme thiab tom qab ntawd hloov mus rau hauv cov khoom. Ob qhov kev xav uas yog, Induced Fit hypothesis thiab Xauv thiab Key hypothesis piav qhia qhov kev khi ntawm lub substrate rau hauv enzyme.
Yuav ua li cas thiaj haum?
Qhov kev ua kom haum yog qhov kev xav uas piav qhia txog kev khi ntawm lub substrate rau hauv ib qho chaw nquag ntawm ib qho enzyme uas tsis muaj qhov tseeb ntawm qhov chaw nquag. Raws li qhov kev xav no, kev pom zoo ntawm qhov chaw nquag hloov pauv mus rau hauv qhov tseeb zoo thaum lub substrate khi.
Daim duab 01: Induced Fit Theory
Kev khi ntawm lub substrate induces kev hloov kho ntawm cov duab ntawm lub active site. Yog li ntawd, lub npe 'Induced haum' yog muab rau qhov kev xav no. Daniel E Koshland tau hais txog qhov kev xav no hauv xyoo 1959. Lub chaw ua haujlwm ntawm cov enzyme tsis zoo li qub raws li qhov kev xav no.
Xauv thiab Key yog dab tsi?
Xauv thiab Ntsiab yog ib qho ntawm cov kev xav uas piav qhia txog hom kev ua ntawm ib qho enzyme uas catalyzes cov tshuaj tiv thaiv. Emil Fischer tau npaj qhov kev xav no hauv xyoo 1894. Raws li kev ntsuas xauv thiab qhov kev xav tseem ceeb, kev khi ntawm lub substrate rau hauv qhov chaw nquag ntawm ib qho enzyme yog sib npaug rau hauv lub xauv thiab qhov tseem ceeb mechanism.
Daim duab 02: Xauv thiab Ntsiab Lus Tseem Ceeb
Lub xauv tshwj xeeb tuaj yeem qhib siv tus yuam sij raug. Ib yam li ntawd, yog tias lub enzyme yog lub xauv, nws yuav qhib tsuas yog los ntawm qhov tseeb substrate uas yog tus yuam sij. Ob leeg haum ib leeg kom raug thiab nruj. Lawv cov duab yog complementary rau ib leeg. Li no, qhov kev khi no yog qhov tshwj xeeb thiab tsis tuaj yeem tawg tau yooj yim.
Dab tsi yog qhov zoo sib xws ntawm Induced Fit thiab Lock thiab Key?
- Ob txoj kev xav piav qhia hom kev ua haujlwm ntawm enzyme.
- Lawv tseem ceeb heev kom nkag siab txog kev khi ntawm cov substrate rau hauv qhov chaw nquag ntawm ib qho enzyme.
Dab tsi yog qhov txawv ntawm Induced Fit thiab Lock thiab Key?
Induced haum thiab xauv thiab qhov tseem ceeb yog ob txoj kev xav uas piav qhia txog hom enzyme. Lub induced haum txoj kev xav piav qhia txog kev khi ntawm ib qho enzyme thiab substrate uas tsis ntxiv thaum lub xauv thiab qhov tseem ceeb piav qhia txog kev khi ntawm enzyme thiab substrate uas yog complementary. Lub chaw ua haujlwm tsis zoo li qub nyob rau hauv tus qauv tsim kom haum thaum nws zoo li qub nyob rau hauv xauv thiab tus qauv tseem ceeb. Cov infographic hauv qab no nthuav tawm qhov sib txawv ntawm Induced Fit thiab Xauv thiab Key hauv daim ntawv teev npe.
Summary – Induced Fit vs Xauv thiab Ntsiab
Qhov kev xav ua kom haum tau piav qhia txog kev khi ntawm enzyme thiab substrate thaum lawv tsis sib haum nrog ib leeg los ntawm lawv cov duab. Kev khi ntawm substrate induces kev hloov pauv ntawm qhov chaw nquag ntawm cov enzyme kom raug khi. Ntawm qhov tod tes, xauv thiab qhov tseem ceeb txoj kev xav piav qhia txog kev khi zoo kawg nkaus los yog haum substrate thiab enzyme. Zoo ib yam li 'xauv thiab yuam sij', substrate thiab enzyme haum nrog ib leeg nruj heev raws li qhov kev xav no. Nyob rau hauv induced haum txoj kev xav, lub active site ntawm lub enzyme tsis zoo li qub thaum nws yog zoo li qub nyob rau hauv lub xauv thiab lub ntsiab mechanism. Qhov no yog qhov sib txawv ntawm induced haum thiab xauv thiab tus yuam sij.
