Key Difference – Blood Clot vs Tissue
Cov ntshav txhaws yog ib qho mesh ua haujlwm ntawm fibrin fibers khiav hauv txhua qhov kev qhia thiab nkag mus rau cov qe ntshav, platelets thiab plasma. Cov ntaub so ntswg, ntawm qhov tod tes, yog ib pawg ntawm cov hlwb tsim los ua ib txoj haujlwm tshwj xeeb yog hu ua cov ntaub so ntswg. Cov ntaub so ntswg sib txawv ua ke los tsim ib lub cev. Hauv qhov kev txiav txim siab ntawd, cov ntshav txhaws tuaj yeem suav tias yog cov khoom siv ntaub so ntswg. Txawm hais tias cov ntaub so ntswg yog cov khoom sib sau ntawm cov hlwb, cov ntshav txhaws yog cov khoom sib txuas ntawm ntau cov ntaub so ntswg uas tau npaj rau kev nkag mus ntawm cov hlwb los ntawm cov hlab ntsha. Qhov no yog qhov sib txawv tseem ceeb ntawm cov ntshav txhaws thiab cov ntaub so ntswg.
Ntshav khov yog dab tsi?
Cov ntshav txhaws yog ib qho mesh ua haujlwm ntawm fibrin fibers mus rau txhua qhov kev qhia thiab nkag mus rau cov qe ntshav, platelets thiab plasma. Cov ntshav txhaws yog ib qho kev tiv thaiv uas siv los ntawm lub cev los tiv thaiv kev poob ntawm cov ntshav thaum cov hlab ntsha tawg lossis thaum cov ntshav nws tus kheej raug puas tsuaj los ntawm qee cov neeg raug mob.
Thaum muaj kev puas tsuaj rau cov hlab ntsha, txoj hauv kev hu ua extrinsic pathway tau qhib. Thaum muaj ntshav raug mob, nws yog txoj hauv kev hauv nruab nrog uas yog qhib. Ob txoj hauv kev no yog cascades ntawm cov tshuaj uas thaum kawg tsim cov prothrombin activator.
Prothrombin activator activates fibrinogen rau hauv fibrin los ntawm ob peb kauj ruam:
Raws li ib txwm muaj, cov ntshav txhaws tsis tsim nyob rau hauv cov hlab ntshav vim muaj ob peb lub txee lub cev tshwj xeeb tshwj xeeb los tiv thaiv cov ntshav tsis tsim nyog.
Mechanisms uas tiv thaiv ntshav txhaws
Endothelial nto yam tseem ceeb
Qhov smoothness ntawm qhov chaw endothelial pab tiv thaiv kev sib cuag ntawm txoj hauv kev. Kuj tseem muaj lub tsho tiv no ntawm glycocalyx ntawm endothelium, uas ua rau cov ntshav txhaws thiab platelets, tiv thaiv kev tsim cov ntshav txhaws.
Lub xub ntiag ntawm thrombomodulin, uas yog ib yam tshuaj muaj nyob rau ntawm endothelium, kuj pab tiv thaiv cov txheej txheem ntawm cov ntshav txhaws. Thrombomodulin khi nrog thrombin thiab nres kev ua haujlwm ntawm fibrinogen.
- Anti-thrombin kev ua ntawm fibrin thiab antithrombin iii.
- Kev ua ntawm heparin
- Lysis ntawm cov ntshav txhaws los ntawm plasminogen
Daim duab 01: Ntshav Ntshav
Txawm hais tias cov kev ntsuas no tshwm sim, cov ntshav txhaws tau tsim tsis zoo hauv cov hlab ntsha. Thaum cov hlab ntsha tuaj yeem nkag mus rau hauv cov hlab ntsha, nws cuam tshuam cov ntshav mus rau cov leeg ntawm qhov chaw tshwj xeeb. Cov khoom lag luam metabolic pov tseg thiab tsis muaj oxygen ua rau ischemia.
Npuas yog dab tsi?
Ib daim ntaub so ntswg yog ib pab pawg ntawm cov hlwb tsim los ua haujlwm tshwj xeeb. Cov ntaub so ntswg sib txawv ua ke los tsim ib lub cev.
Cov hlwb uas ua rau cov ntaub so ntswg tshwj xeeb muaj kev hloov pauv tshwj xeeb kom ua haujlwm tau zoo txhawm rau tswj lawv cov qauv kev ncaj ncees thiab kev ua haujlwm muaj peev xwm ntawm qib siab.
Daim duab 02: Hom Ntiv
Ib yam piv txwv ntawm lub cev nqaij daim tawv tau hais hauv qab no.
- paj hlwb → tswj tag nrho cov haujlwm metabolic thiab lub cev
- Cov nqaij mos thiab lwm yam kev sib txuas → Koom nrog hauv kev txav ntawm lub cev thiab tswj cov qauv thiab ruaj khov ntawm lub cev nqaij daim tawv
- Cov ntaub so ntswg epithelial → Npog lub ntsej muag ntawm lub cev
Dab tsi yog qhov zoo sib xws ntawm cov ntshav txhaws thiab cov ntaub so ntswg?
Cells koom nrog tsim cov ntaub so ntswg thiab cov ntshav txhaws
Dab tsi yog qhov txawv ntawm cov ntshav txhaws thiab cov ntaub so ntswg?
ntshav txhaws vs ntaub so ntswg |
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| Ib ntshav txhaws yog ib qho mesh ua haujlwm ntawm fibrin fibers khiav hauv txhua qhov kev qhia thiab nkag mus rau cov qe ntshav, platelets thiab plasma. | Ib pawg ntawm cov hlwb tsim los ua ib txoj haujlwm tshwj xeeb yog hu ua cov ntaub so ntswg. Cov ntaub so ntswg sib txawv ua ke los tsim ib lub cev. |
| Sau cov Cells | |
| Ib qho ntshav txhaws tsis yog ib qho ntawm cov hlwb. | Ib daim ntaub so ntswg yog sau los ntawm hlwb. |
| Kev ua haujlwm ntawm cov ntshav txhaws yog txhawm rau tiv thaiv kev poob ntshav. | Kev ua haujlwm ntawm cov ntaub so ntswg txawv ntawm ib hom mus rau lwm qhov. |
Summary – Blood Clot vs Tissue
Cov ntshav txhaws yog ib qho mesh ua haujlwm ntawm fibrin fibers khiav hauv txhua qhov kev qhia thiab nkag mus rau cov qe ntshav, platelets thiab plasma thaum cov ntaub so ntswg yog ib pab pawg ntawm cov hlwb los ua haujlwm tshwj xeeb. Qhov sib txawv tseem ceeb ntawm cov ntshav khov thiab cov ntaub so ntswg yog tias cov ntshav txhaws muaj cov khoom sib txuas ntawm cov ntaub so ntswg, tab sis cov ntaub so ntswg muaj cov cell.
