Qhov Tseem Ceeb Qhov txawv - Streptolysin O vs Streptolysin S
Streptolysin suav tias yog streptococcal hemolytic exotoxin. Hauv cov ntsiab lus yooj yim, nws yog hemolysin tsim los ntawm cov kab mob Streptococcus. Hemolysins yog cov sib txuas uas tuaj yeem yog lipids lossis cov proteins uas muaj peev xwm ua rau kev puas tsuaj ntawm cov qe ntshav liab los ntawm lysis. Muaj ntau hom streptolysin xws li streptolysin O (SLO), streptolysin S (SLS), thiab lwm yam. Streptolysin O yog active tsuas yog thaum lub sij hawm tej yam kev mob ntawm reversibly txo lub xeev thiab Streptolysin S yog ruaj khov nyob rau hauv tej yam kev mob uas muaj oxygen nyob rau hauv ntau dua concentrations. Yog li, streptolysin O yog suav tias yog oxygen labile thiab streptolysin S yog suav tias yog oxygen ruaj khov. Qhov no yog qhov sib txawv tseem ceeb ntawm Streptolysin O thiab Streptolysin S.
YStreptolysin O yog dab tsi?
Streptolysin O (SLO) yog cov khoom sib xyaw uas yog oxygen labile. Hauv lwm cov ntsiab lus, Streptolysin O tsuas yog ua haujlwm thaum lub sijhawm cov xeev txo qis. Nws muaj cov yam ntxwv antigenic. Piv rau Streptolysin S, Streptolysion O yog qhov loj dua. Qhov ntawd yog ib qho laj thawj tseem ceeb vim li cas nws muaj cov khoom antigenic. Hais txog nws txoj haujlwm, Streptolysin O feem ntau cuam tshuam rau kev tawg ntawm cov qe ntshav liab (hemolysis). Zoo ib yam li streptolysin S, streptolysin O yog suav tias yog streptococcal hemolytic exotoxin uas feem ntau tsim los ntawm Pawg A Streptococcus. Targeted cells ntawm streptolysin O yog cov hlwb myocardial, epithelial cells, platelets, thiab neutrophils.
Daim duab 01: Pab Pawg A Streptococcus Bacteria
Cov tshuaj tiv thaiv uas tsim tawm tawm tsam streptolysin O yog antistreptolysin O (ASO). ASO yog tsim thaum lub cev kis tus kab mob. Thaum lub sij hawm xws li kis mob, lub cev tsim ntau hom tshuaj tiv thaiv tiv thaiv antigens ntawm Streptococcus. Yog li, ASO yog ib hom antigen tsim. Cov qib siab ntawm ASO qhia qhov tshwm sim ntawm yav dhau los lossis tam sim no tus kab mob. Qhov ASO no tau siv los ua tus cim thaum ntxov ntawm kev kis kab mob thaum lub sijhawm kuaj mob ntawm tus mob rheumatic fever. Kev tsim cov tshuaj tiv thaiv kab mob tshwm sim raws li cov lus teb rau qhov raug rau cov kab mob. Tab sis thaum muaj qee yam mob, tus neeg mob yuav asymptomatic txawm tias tom qab kis tus kab mob thiab tsis tsim ASO.
Streptolysin S yog dab tsi?
Streptolysin S yog cov pa ruaj khov hemolysin tsim los ntawm hom Streptococcus. Streptolysin S tsis yog suav tias yog cov tshuaj tiv thaiv kab mob vim nws qhov me me, uas yog kwv yees li 2.8kd ua. Nws kuj tseem hu ua cardiotoxic exotoxin, uas yog ib hom beta-hemolytic tivthaiv. Streptolysin S yog ib hom tshuaj lom ntawm tes uas muaj peev xwm cuam tshuam rau ntau hom hlwb xws li platelets, neutrophils, thiab lwm yam. Cov hemolysins no kuj tuaj yeem cuam tshuam rau subcellular organelles. Lwm yam tshaj li cov hom phiaj hlwb streptolysin S muaj peev xwm ua rau muaj kev cuam tshuam cytotoxic ntawm myocardial cells thiab epithelial cells.
Streptolysin S yog hom streptolysin loj uas yog lub luag haujlwm rau phenotype ntawm beta hemolysis ntawm pawg A streptolysin (GAS). Qhov no suav nrog kev pab txhawb rau pathogenesis uas tshwm sim los ntawm kev hloov kho ntawm lub cev tiv thaiv kab mob uas tshwm sim thaum lub sijhawm ntxov ntawm kev txhim kho ntawm tus kab mob. Tsis tas li ntawd, inhibition ntawm neutrophil opsonophagocytosis tsuas yog ua rau cov txheej txheem pathogenesis.
Dab tsi yog qhov zoo sib xws ntawm Streptolysin O thiab Streptolysin S?
- Ob leeg Streptolysin O thiab Streptolysin S yog hemolysins tsim los ntawm Streptococcus spp.
- Ob leeg Streptolysin O thiab Streptolysin S yog qhov ua rau muaj kab mob.
Qhov txawv ntawm Streptolysin O thiab Streptolysin S yog dab tsi?
YStreptolysin O vs Streptolysin S |
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| Streptolysin O yog cov pa oxygen labile hemolysin tsim los ntawm Streptococcus hom | Streptolysin S yog cov pa ruaj khov hemolysin tsim los ntawm Streptococcus hom |
| Antigenicity | |
| Tam sim no hauv Streptolysin O. | Tsis muaj nyob hauv Streptolysin S. |
Summary – Streptolysin O vs Streptolysin S
Y Streptolysin yog streptococcal hemolytic exotoxin. Hauv cov ntsiab lus yooj yim, nws yog hemolysin tsim los ntawm cov kab mob Streptococcus. Hauv cov ntsiab lus ntawm ntau hom streptolysin, streptolysin O (SLO) thiab streptolysin S (SLS) yog ob hom. Streptolysin O (SLO) yog ib qho tshuaj uas yog oxygen labile. Hauv lwm cov ntsiab lus, Streptolysin O tsuas yog ua haujlwm thaum lub sijhawm cov xeev txo qis. Cov tshuaj tiv thaiv uas tsim tawm tawm tsam streptolysin O yog anti-streptolysin O (ASO). ASO yog tsim thaum lub cev kis tus kab mob. Streptolysin S yog ib qho oxygen ruaj khov hemolysin tsim los ntawm Streptococcus hom. Streptolysin S tsis yog suav tias yog cov tshuaj tiv thaiv kab mob vim nws qhov me me. Qhov no yog qhov txawv ntawm Streptolysin O thiab Streptolysin S.
