Qhov Tseem Ceeb - D Dimer vs FDP
Fibrinogen yog ib qho ntawm cov khoom tseem ceeb koom nrog hauv cov txheej txheem ntshav txhaws. Fibrinogen yog cov protein uas cov fibrin network tsim thaum raug mob rau cov ntaub so ntswg. Cov txheej txheem no hu ua ntshav txhaws. Fibrinolysis yog txheej txheem uas cov fibrin tawg los ntawm kev ua ntawm plasmin. Cov khoom degradation no hu ua Fibrin Degradation Products (FDPs). Fibrin Degradation Product lossis FDP yog cov khoom lag luam ntawm fibrinolysis uas tseem tshuav tom qab cov ntshav tau yaj. D Dimer yog cov khoom kawg ntawm fibrin degradation thiab yog ib hom FDP. Qhov sib txawv tseem ceeb ntawm FDP thiab D Dimer yog cov qauv. FDP tsis muaj qhov txuas ntxiv ntawm D thiab E subunits ntawm Fibrin, qhov D dimer yog tsim los ntawm kev sib txuas ntxiv.
D Dimer yog dab tsi?
D Dimer yog qhov kawg ntawm cov khoom ntawm fibrinolysis. Nws yog hom Fibrin Degradation Product. Nws muaj qhov hnyav molecular ntawm 180 kDa thiab yog tsim los ntawm kev sib txuas ntxiv nrog D thiab E subunits ntawm fibrin. Yog li, D dimer yog tsim los ntawm cov seem ntawm tag nrho peb chains ntawm fibrinogen uas yog hu ua; alpha, beta thiab gamma. Cov chains no yog sib txuas nrog cov nyiaj disulfide. D Dimer tau txais cov qauv dimeric raws li lub npe qhia. Cov qauv dimeric ntawm D dimer yog tuav los ntawm isopeptide bonds ntawm gamma chains. Lawv yog covalent bonds intermolecular.
Daim duab 01: D Dimer
Kev kuaj D dimer yog ib qho kev sim ua rau kev soj ntsuam ntawm kev mob plawv thiab atherosclerosis. D dimer theem ntawm cov tib neeg noj qab haus huv nyob qis dua 0.5 µg / ml whereas, nce qib qhia thrombosis, pulmonary embolism thiab atherosclerosis. Monoclonal antibodies yog siv nyob rau hauv D dimer kuaj kom paub meej cov qib ntawm cov tshuaj tiv thaiv. Qhov kev sim no yog qhov yuam kev ntau vim muaj ntau FDPs zoo ib yam li D dimer.
FDP yog dab tsi?
Fibrin Degradation Product lossis FDP yog cov seem ntawm fibrinolysis, thiab yog txheej txheem uas cov ntshav txhaws tau yaj lossis tawg. FDPs tseem nyob hauv cov hlab ntsha thaum fibrinolysis. Thaum cov ntaub so ntswg raug mob, cov ntshav txhaws, platelets thiab lwm yam cofactors sib xyaw ua ke los tsim ib lub network zoo ntawm fibrin uas yuav ua raws li lub vas hla qhov raug mob kom txog thaum nws zoo. Thaum cov txheej txheem kho cov ntaub so ntswg ua tiav, cov ntshav txhaws tau tawg thiab yaj los ntawm cov txheej txheem enzymatic uas siv Plasmin. Txoj kev sib txuas ntawm fibrin network yog disintegrated los tsim FDPs.
Daim duab 02: FDP
FDP kuaj yog ua los tshuaj xyuas kev mob plawv thiab atherosclerosis. Zoo ib yam li D dimer kuaj, nce qib ntawm FDP yuav qhia thrombosis, atherosclerosis thiab pulmonary embolism.
Dimer qhov sib xws ntawm D Dimer thiab FDP yog dab tsi?
- Ob D Dimer thiab EDP yog cov khoom degradation ntawm fibrinolysis
- Ob qho D Dimer thiab EDP molecules raug tshuaj xyuas rau thrombosis, atherosclerosis thiab pulmonary embolism.
- Ob qhov kev xeem uas suav nrog FDP thiab D dimer tau ua tiav raws li kev sim coagulation.
- Plasmin koom nrog hauv kev degradation ntawm fibrin, kom tawm los ntawm FDP thiab D dimer.
Dimer qhov txawv ntawm D Dimer thiab FDP yog dab tsi?
D Dimer vs FDP |
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| D Dimer yog cov khoom kawg ntawm fibrin degradation thiab yog ib hom FDP. | Fibrin Degradation Product lossis FDP yog cov khoom lag luam ntawm fibrinolysis uas tseem tshuav tom qab cov ntshav tau yaj lawm. |
| qauv | |
| D Dimer yog ib qho qauv dimeric. | EDP tuaj yeem yog cov qauv mesh zoo li yooj yim. |
Summary – D Dimer vs FDP
D dimer thiab FDP yog cov khoom lag luam degradation ntawm fibrinolysis, qhov feem ntau cov khoom lag luam dimeric kawg yog D dimer. Fibrinolysis, los yog degradation ntawm fibrin network yuav siv sij hawm qhov chaw raws li ib tug post tshwm sim rau cov txheej txheem ntawm cov ntshav txhaws. Plasmin koom nrog hauv cov txheej txheem degradation uas yuav ua rau FDP thiab D dimers. Ob qho tib si no yog siv los ua cov qauv kuaj sim los ntsuas qhov kev pheej hmoo ntawm atherosclerosis. Qhov no yog qhov txawv ntawm D Dimer thiab FDP.
