Qhov Tseem Ceeb Qhov txawv - Holoenzyme vs Apoenzyme
Enzymes yog cov tshuaj lom neeg lom neeg uas ua rau muaj kev cuam tshuam tshuaj lom neeg hauv lub cev. Lawv yog cov proteins ua los ntawm cov amino acid sequences. Enzymes koom nrog cov tshuaj tiv thaiv tsis tau noj. Lawv yog cov tshwj xeeb rau substrates thiab tshuaj tiv thaiv. Kev ua haujlwm ntawm cov enzyme yog txhawb los ntawm ntau yam tsis yog-proteinaceous me me molecules. Lawv hu ua cofactors. Lawv pab cov enzymes hauv lawv cov kev ua haujlwm catalytic. Cov cofactors tuaj yeem yog hlau ions lossis coenzymes; lawv kuj tuaj yeem yog inorganic lossis organic molecules. Ntau cov enzymes xav tau cofactor los ua haujlwm thiab pib ua haujlwm catalytic. Raws li kev khi nrog cofactor, enzymes muaj ob hom npe hu ua apoenzyme thiab holoenzyme. Qhov sib txawv tseem ceeb ntawm holoenzyme thiab apoenzyme yog tias apoenzyme yog cov protein tivthaiv ntawm cov enzyme uas tsis ua haujlwm thiab tsis khi rau cofactor thaum holoenzyme yog cov protein tivthaiv ntawm cov enzyme thiab khi cofactor uas tsim cov active daim ntawv ntawm cov enzyme.
Holoenzyme yog dab tsi?
Enzymes yog cov proteins uas ua rau cov tshuaj biochemical hauv cov hlwb. Feem ntau cov enzymes xav tau ib qho me me uas tsis yog protein molecule los pib ua haujlwm catalytic. Cov molecules no hu ua cofactors. Cofactors feem ntau yog inorganic lossis organic molecules. Cofactors tau muab faib ua ob hom tseem ceeb hu ua hlau ions thiab coenzymes. Kev khi ntawm cofactor yog qhov tseem ceeb rau kev ua kom lub enzyme thiab pib ntawm cov tshuaj tiv thaiv tshuaj. Thaum cov protein tivthaiv ntawm cov enzyme yog khi rau cofactor, tag nrho cov molecule hu ua holoenzyme. Holoenzyme yog catalytically active. Li no, nws nquag khi nrog cov substrates thiab nce tus nqi ntawm cov tshuaj tiv thaiv. Coenzymes xoob khi nrog cov enzymes thaum cov pab pawg prosthetic khi nruj nrog cov apoenzymes. Qee cov cofactors khi rau qhov chaw ua haujlwm ntawm enzyme. Thaum khi, nws hloov pauv qhov kev sib haum xeeb ntawm cov enzyme thiab txhim kho txoj kev khi ntawm cov substrates mus rau qhov chaw nquag ntawm cov enzyme.
DNA polymerase thiab RNA polymerase yog ob lub holoenzymes. DNA polymerase xav tau magnesium ions los ua haujlwm thiab pib DNA polymerization. RNA polymerase xav tau sigma yam rau nws txoj haujlwm catalytic.
Apoenzyme yog dab tsi?
Apoenzyme yog cov enzyme ua ntej khi nrog cov cofactor. Hauv lwm lo lus, apoenzyme yog cov protein ib feem ntawm cov enzyme uas tsis muaj cofactor. Apoenzyme yog catalytically tsis ua haujlwm thiab tsis tiav. Nws tsim ib qho kev ua haujlwm enzyme thaum sib txuas nrog coenzyme thiab txiav txim siab qhov tshwj xeeb ntawm cov kab ke no rau lub substrate. Muaj ntau ntau cofactors uas khi nrog apoenzymes ua holoenzymes. Cov coenzymes feem ntau yog NAD +, FAD, Coenzyme A, B vitamins thiab vitamin C. Cov hlau ions uas khi nrog apoenzymes yog hlau, tooj liab, calcium, zinc, magnesium, thiab lwm yam. Cofactors khi nruj los yog xoob nrog cov apoenzyme los hloov apoenzyme rau hauv holoenzyme. Thaum cov cofactor raug tshem tawm ntawm holoenzyme, nws tau hloov dua siab tshiab rau hauv apoenzyme, uas tsis ua haujlwm thiab tsis tiav.
Qhov muaj cov cofactor ntawm qhov chaw nquag ntawm apoenzyme yog qhov tseem ceeb vim tias lawv muab cov pab pawg lossis cov chaw uas cov protein ib feem ntawm cov enzyme tsis muaj los catalyze cov tshuaj tiv thaiv.
Daim duab 01: Apoenzyme thiab Holoenzyme
Qhov txawv ntawm Holoenzyme thiab Apoenzyme yog dab tsi?
Holoenzyme vs Apoenzyme |
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| Holoenzyme yog ib qho enzyme uas muaj cov apoenzyme khi rau nws cov cofactor. | Apoenzyme yog cov protein tivthaiv uas tsis muaj nws cov cofactor. |
| Holoenzyme yog khi rau nws cov cofactor. | Apoenzyme yog cov enzyme tivthaiv yam tsis muaj cofactor. |
| Kev ua haujlwm | |
| Holoenzyme yog catalytically active. | Apoenzyme yog catalytically tsis ua haujlwm. |
| Holoenzyme ua tiav thiab tuaj yeem pib cov tshuaj tiv thaiv. | Apoenzyme tsis tiav thiab tsis tuaj yeem pib qhov tshuaj tiv thaiv. |
| Examples | |
| DNA polymerase, RNA polymerase yog piv txwv ntawm holoenzym. | Aspartate transcarbamoylase yog ib qho piv txwv rau apoenzyme. |
Summary – Holoenzyme vs Apoenzyme
Enzymes yog cov khoom siv roj ntsha ntawm cov hlwb. Lawv txo qis lub zog xav tau rau qhov tshwm sim tshwm sim. Enzymes nce tus nqi ntawm cov tshuaj tiv thaiv los ntawm nquag inducing lub substrate hloov mus rau cov khoom. Lawv tshwj xeeb catalyze cov tshuaj tiv thaiv yam tsis tau nkag mus rau hauv cov tshuaj tiv thaiv. Enzymes yog tsim los ntawm cov protein molecules. Cov protein feem ntawm cov enzyme hu ua apoenzyme. Apoenzyme xav tau kev khi nrog cov tsis muaj proteinacious me me molecules hu ua cofactors kom ua haujlwm. Thaum apoenzyme khi nrog cofactor, lub complex hu ua holoenzyme. Holoenzyme yog catalytically active los pib cov tshuaj tiv thaiv. Lub substrate khi nrog holoenzyme, tsis yog nrog apoenzyme. Qhov no yog qhov txawv ntawm holoenzyme thiab apoenzyme.
Download PDF Version ntawm Holoenzyme vs Apoenzyme
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li cov ntawv sau tseg. Thov download PDF version ntawm no Qhov txawv Ntawm Holoenzyme thiab Apoenzyme.
