Qhov Tseem Ceeb - Thrombocytopenia vs Hemophilia
Qhov muaj qhov txawv txav ntawm cov ntshav qis hauv cov ntshav yog hu ua thrombocytopenia. Nws tsis muaj cov tshuaj genetic predisposition thiab feem ntau yog vim muaj ntau yam ua rau ua rau tsis zoo rau kev tsim cov platelets. Nyob rau tib lub sijhawm, nws yog qhov tsim nyog los txiav txim siab thrombocytopenia ua ib qho kev kuaj mob es tsis yog ib tus kab mob. Sib nrug los ntawm thrombocytopenia thiab ib txhais tes ntawm ob peb lwm yam mob, feem ntau ntawm cov kab mob hematological yog vim muaj kev cuam tshuam ntawm caj ces feem ntau kis mus rau tiam tom ntej ntawm cov xeeb ntxwv ntawm cov poj niam nqa khoom. Hemophilia yog ib yam kab mob hematological uas yuav luag pom tsuas yog hauv cov txiv neej uas yog vim qhov tsis txaus ntawm yam VIII lossis yam IX. Qhov sib txawv tseem ceeb ntawm thrombocytopenia thiab hemophilia yog tias thrombocytopenia yog qhov txo qis hauv platelet theem thaum hemophilia yog qhov txo qis hauv qhov concentration ntawm yam VIII lossis IX.
YThrombocytopenia yog dab tsi?
Qhov muaj qhov txawv txav ntawm cov ntshav qis hauv cov ntshav yog hu ua thrombocytopenia. Cov neeg mob uas muaj tus kab mob no muaj ib tug nyiam los ntshav, thiab los ntshav prominently tshwm sim los ntawm me me capillaries thiab venules es tsis yog los ntawm cov hlab ntsha loj. Yog li ntawd, tuaj yeem muaj ntau yam hemorrhages thoob plaws hauv lub cev. Nyob rau ntawm daim tawv nqaij, qhov no yog manifested raws li ib tug thrombocytic purpura uas yog yus muaj los ntawm lub xub ntiag ntawm me me purplish blotches.
Kev ntshav tsis tshwm sim kom txog thaum qib platelet poob qis dua 50000/.
Tshuaj Kho Mob
- Petechiae
- Nyob los ntshav txawm tias tom qab raug mob me
- Qhia los ntawm cov pos hniav
- Hematuria
- mob khaub thuas hnyav
- Yellowish discoloration ntawm daim tawv nqaij (jaundice)
Nyob zoo ib tsoom niam txiv kwv tij neej tsas sawv daws
Daim duab 01: Thrombocytic Purpura
Caus
- Splenomegaly
- YIdiopathic thrombocytopenia
- Kev haus dej cawv ntau ntau
- kis kab mob xws li kab mob siab C
- Kev cev xeeb tub
- Cov teebmeem ntawm cov tshuaj sib txawv xws li heparin
- YHemolytic uremic syndrome
Kev tshawb nrhiav
Cov ntshav suav tag nrho tuaj yeem pom qhov qis qis ntawm cov platelets. Kev tshawb nrhiav ntxiv tej zaum yuav xav tau raws li kev soj ntsuam kev xav tsis thoob ntawm cov kab mob hauv qab.
Kev tswj hwm
- Yog tias thrombocytopenia yog vim lub cev tiv thaiv kab mob, cov tshuaj tiv thaiv kab mob yuav tsum tau noj. Corticosteroids yog cov tshuaj xaiv los tiv thaiv cov txheej txheem inflammatory thiab txhawb cov platelet ntau lawm
- Ib theem qis qis ntawm platelets yuav xav tau kev hloov pauv tam sim ntawm cov khoom siv ntshav thiab cov platelets kom tsis txhob muaj kev phom sij txog txoj sia
- Yog hais tias splenomegaly yog qhov ua rau thrombocytopenia, kev phais ntawm tus po yog qhov tsim nyog.
- Ntau lwm yam kev kho mob thiab kev phais mob yuav tsum tau nyob ntawm seb muaj kab mob hauv qab
Hemophilia yog dab tsi?
Hemophilia yog ib qho kab mob hematological uas yuav luag pom hauv cov txiv neej. Feem ntau ntawm cov neeg mob, tus kab mob no yog vim qhov tsis txaus ntawm cov ntshav txhaws VIII nyob rau hauv cov ntaub ntawv nws yog hu ua classic hemophilia los yog hemophilia A. Lwm yam tsis tshua pom daim ntawv ntawm hemophilia, uas yog hu ua hemophilia B, yog vim li cas. qhov tsis txaus ntawm cov ntshav txhaws IX.
Cov qub txeeg qub teg ntawm ob yam no yog los ntawm poj niam chromosomes. Yog li ntawd, txoj hauv kev ntawm tus poj niam tau txais hemophilia yog qhov tsawg heev vim nws tsis zoo li ob qho tib si ntawm lawv cov chromosomes yuav hloov pauv ib txhij. Cov poj niam uas ib leeg chromosome tsis txaus yog hu ua hemophilia carriers.
Daim duab 02: Kev Sib Txuas Ntawm Kab Mob Hemophilia
Tshuaj Kho Mob
Hemophilia hnyav (qhov concentration tsawg dua 1IU/dL)
Qhov no yog qhov tshwm sim los ntawm qhov tshwm sim los ntawm kev ua neej nyob thaum ntxov, feem ntau mus rau cov pob qij txha thiab cov leeg. Yog tias tsis kho kom raug, tus neeg mob tuaj yeem sib koom ua ke deformities thiab tuaj yeem ua rau tuag taus.
Moderate Hemophilia (qhov concentration ntawm 1-5 IU/dL)
Qhov no cuam tshuam nrog los ntshav hnyav tom qab raug mob thiab qee zaus los ntshav.
Mild Hemophilia (yam muaj ntau dua 5 IU/dL)
Tsis muaj qhov tshwm sim los ntshav hauv tus mob no. Los ntshav tsuas yog tom qab raug mob lossis thaum phais.
Kev tshawb nrhiav
- Lub Sijhawm Prothrombin yog qhov qub
- APTT tau nce
- Tus yam VIII lossis qib IX qib qis qis qis
Kev kho mob
Kev txhaj tshuaj ntawm qhov chaw VIII lossis qhov IX kom normalize lawv qib
Ib nrab-lub neej ntawm yam VIII yog 12 teev. Yog li ntawd nws yuav tsum tau tswj hwm tsawg kawg ob zaug hauv ib hnub kom tswj tau cov qib tsim nyog. Ntawm qhov tod tes, nws yog qhov txaus rau infuse yam IX ib zaug hauv ib lub lis piam vim tias nws muaj lub neej ntev dua ntawm 18 teev.
Dab tsi zoo sib xws ntawm Thrombocytopenia thiab Hemophilia?
- Ob leeg yog cov kab mob hematological.
- Cov ntshav tsis txawv txav yog qhov tshwm sim thiab tseem ceeb tshaj plaws hauv kev kho mob ntawm ob qho tib si thrombocytopenia thiab hemophilia.
Qhov txawv ntawm Thrombocytopenia thiab Hemophilia yog dab tsi?
Thrombocytopenia vs Hemophilia |
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| Qhov muaj cov ntshav qis qis hauv cov ntshav yog hu ua thrombocytopenia. | Hemophilia yog ib yam kab mob hematological uas yuav luag pom hauv cov txiv neej. |
| Muaj platelets tsis txaus. | Muaj qhov tsis txaus ntawm qhov VIII lossis qhov IX. |
| Ntshav ntshav feem ntau tshwm sim los ntawm me me capillaries thiab venules. | Cov hlab ntsha loj yog qhov chaw uas muaj ntshav ntau tshaj plaws hauv hemophilia. |
| Qhov no tsis yog kab mob caj ces. | Nov yog kab mob caj ces. |
| Tus neeg mob | |
| Txhua tus txiv neej thiab poj niam sib npaug. | Qhov no yuav luag cuam tshuam rau txiv neej. |
| Tshuaj Kho Mob | |
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Qhov chaw kho mob tseem ceeb tshaj plaws yog, · Petechiae · Ib qho yooj yim bruis · Ntev los ntshav txawm tias tom qab raug mob me · Los ntshav los ntawm cov pos hniav · Epistaxis · Hematuria · mob khaub thuas hnyav heev · Yellowish discoloration ntawm daim tawv nqaij (jaundice) |
Daim duab kho mob txawv nyob ntawm qhov mob hnyav. · mob hemophilia (qhov concentration tsawg dua 1IU/dL) Muaj los ntshav los ntawm lub neej thaum ntxov feem ntau mus rau hauv cov pob qij txha thiab cov leeg. Qhov tsis muaj kev kho mob zoo tuaj yeem ua rau muaj kev sib koom ua ke · Nruab nrab hemophilia (feem ntau concentration yog nyob nruab nrab ntawm 1-5 IU / dL) Qhov no cuam tshuam nrog los ntshav hnyav tom qab raug mob thiab qee zaus los ntshav. · Me me hemophilia (qhov concentration ntau dua 5 IU/dL) Tsis muaj qhov tshwm sim los ntshav hauv tus mob no. Los ntshav tsuas yog tom qab raug mob lossis thaum phais. |
| Caus | |
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feem ntau ua rau thrombocytopenia yog, · Splenomegaly · Leukemia · Idiopathic thrombocytopenia · Chronic alcoholism · kis kab mob xws li kab mob siab C · Cev xeeb tub · Cov teebmeem ntawm cov tshuaj sib txawv xws li heparin · Hemolytic uremic syndrome |
Hemophilia yog ib yam kab mob hauv lub cev uas tsis paub qhov ua rau kis tau. |
| Kev tshawb nrhiav | |
| Cov ntshav suav tag nrho tuaj yeem qhia qhov qis qis ntawm cov platelets. |
Kev kuaj mob yog los ntawm cov txiaj ntsig ntawm kev tshawb nrhiav hauv qab no · Lub Sijhawm Prothrombin - ib txwm · APTT – nce · Tus yam VIII lossis qib IX theem- qis qis |
| Kev tswj hwm | |
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· Yog tias thrombocytopenia yog vim kev tiv thaiv kab mob, cov tshuaj tiv thaiv kab mob yuav tsum tau muab tshuaj. Corticosteroids yog cov tshuaj xaiv los tiv thaiv cov txheej txheem inflammatory thiab txhawb cov platelet ntau lawm · Cov ntshav qis qis qis yuav tsum tau muab cov khoom siv ntshav thiab cov platelets hloov tam sim kom tsis txhob muaj teeb meem rau lub neej. · Yog hais tias splenomegaly yog qhov ua rau thrombocytopenia, kev phais ntawm tus po yog tsim nyog. · Lwm yam kev kho mob thiab kev phais yuav tsum tau muaj nyob ntawm seb cov kab mob hauv qab no. |
Kev txhaj tshuaj ntawm cov tshuaj VIII lossis yam IX kom normalize lawv qib yog qhov tseem ceeb hauv kev tswj hwm ntawm hemophilia. |
Summary – Thrombocytopenia vs Hemophilia
Qhov muaj qhov txawv txav ntawm cov ntshav qis hauv cov ntshav yog hu ua thrombocytopenia. Hemophilia, ntawm qhov tod tes, yog ib qho kab mob hematological tshwm sim los ntawm qhov tsis txaus ntawm yam VIII lossis yam IX thiab yuav luag pom hauv cov txiv neej. Qhov tseem ceeb sib txawv ntawm thrombocytopenia thiab hemophilia yog tias nyob rau hauv thrombocytopenia qib platelet poob qis, tab sis nyob rau hauv hemophilia, nws yog qhov concentration ntawm factor VIII los yog factor IX uas txawv txav.
