Qhov Tseem Ceeb - Sarcoidosis vs Tuberculosis
Sarcoidosis thiab Tuberculosis yog ob yam kab mob ntawm qhov sib txawv tseem ceeb tuaj yeem txheeb xyuas. Sarcoidosis nyob rau hauv cov kab mob uas tsis yog-kab mob sib kis nrog cov kab mob uas tsis yog-caseating granuloma thaum tuberculosis yog kab mob kis los ntawm Mycobacterium tuberculosis nrog caseation necrosis. Qhov no yog qhov sib txawv tseem ceeb ntawm Sarcoidosis thiab Tuberculosis. Los ntawm kab lus no cia peb tshawb xyuas qhov sib txawv no ntxiv.
Sarcoidosis yog dab tsi?
Sarcoidosis yog ib yam kab mob tiv thaiv kab mob. Nws yog tus cwj pwm los ntawm kev tsim granuloma yog ntau cov ntaub so ntswg. Granuloma secretes ntau yam tshuaj xws li 25 (OH) 2vitamin D3, uas ua rau cov calcium ntau hauv cov ntshav. Cov neeg mob yuav tau txais ntau yam kev mob tshwm sim xws li lymph node o, mob ntsws fibrosis, mob caj dab, tshwm sim ntawm daim tawv nqaij, thiab lwm yam. Qee zaum kev cuam tshuam ntawm cov hlab ntsha tuaj yeem tshwm sim uas hu ua neuro-sarcoidosis. Qhov no yog ib qho kev mob loj zuj zus mus ntev nrog kev koom tes hauv ntau qhov system. Kev kuaj mob yog ua raws li cov tsos mob thiab cov cim qhia uas txhawb nqa cov qib angiotensin-hloov enzyme (ACE) thiab qib calcium hauv cov ntshav. CT scan yuav qhia cov yam ntxwv xws li lymphadenopathy thiab mob ntsws. Yog tias kuaj pom ntxov tuaj yeem tswj tau zoo nrog cov tshuaj steroids uas tuaj yeem tswj tau lub cev tiv thaiv kab mob ntau dhau. Xwb, cov tshuaj uas feem ntau siv los kho mob qog noj ntshav thiab tiv thaiv lub cev tiv thaiv kab mob, xws li methotrexate, azathioprine, thiab leflunomide, tuaj yeem siv.
Tuberculosis yog dab tsi?
Tuberculosis yog tshwm sim los ntawm mycobacterium hu ua Mycobacterium tuberculosis. Tuberculosis muaj ob hom pulmonary thiab extrapulmonary. Pulmonary tuberculosis yog tus cwj pwm los ntawm cavitation ntawm lub ntsws thiab kev puas tsuaj ntawm lub ntsws parenchyma. Tuberculosis feem ntau tshwm sim ntawm cov neeg tiv thaiv kab mob xws li cov neeg quav yeeb tshuaj, cov neeg mob ntshav qab zib. Cov tsos mob tshwm sim yog hnoos ntev, hemoptysis lossis dhau ntshav nrog hnoos qeev, yav tsaus ntuj pyrexia, hws hmo ntuj, tsis qab los noj mov thiab poob ceeb thawj. Txhua lub cev tuaj yeem koom nrog hauv tuberculosis thiab piv txwv yog TB meningitis, TB mob caj dab, thiab lwm yam. Kev kuaj mob yog los ntawm microbiological kev pom zoo ntawm TB bacilli hauv cov ntaub so ntswg. Cov txheej txheem sib txawv yog siv los kuaj tus kab mob TB nrog rau cov kua qaub nrawm, kab lis kev cai, thiab cov tshuaj tiv thaiv polymerase saw. X-ray thiab CT scan yuav pab tau rau kev kuaj mob. Kev kho mob yog los ntawm kev kho cov tuberculous uas suav nrog isoniazid, rifampicin, pyrazinamide, thiab ethambutol. Muaj ntau txoj kev kho mob sib txawv, thiab kev ua raws cai ntev yog qhov tseem ceeb thaum lub sijhawm kho. TB tuaj yeem kho tau zoo nrog cov tshuaj muaj tam sim no. Muaj lwm yam tshuaj sib txawv los kho tus kab mob TB. Cov tshuaj tiv thaiv BCG yog siv los tiv thaiv kev kis tus kab mob hauv cov menyuam yaus. Nws yog muab thaum yug los rau tag nrho cov me nyuam raws li kev txhaj tshuaj intradermal. Kev kuaj Mantoux yog siv los txheeb xyuas qhov kis tau tus kab mob yav dhau los. Nws yuav zoo txawm tias txhaj tshuaj tiv thaiv BCG. Txawm li cas los xij, kev sim Mantoux yuav ua rau muaj txiaj ntsig zoo hauv tus neeg mob TB, thiab nws yog qhov kev tshawb nrhiav tseem ceeb.
Dab tsi yog qhov txawv ntawm Sarcoidosis thiab Tuberculosis?
Yam ntxwv ntawm Sarcoidosis thiab Tuberculosis:
Cause:
Tuberculosis yog tshwm sim los ntawm Mycobacterium tuberculosis, thiab nws yog kab mob sib kis.
Sarcoidosis yog ib hom kab mob tiv thaiv kab mob uas tsis muaj tus kab mob kis tau.
History:
Tuberculosis caseating granulomas.
Sarcoidosis ua rau tsis yog caseating granulomas.
Symptoms:
Ib hnoos ntev thiab hemoptysis yog qhov tseem ceeb hauv pulmonary tuberculosis vim cavitation ntawm lub ntsws.
Ua pa nyuaj yog qhov tseem ceeb hauv pulmonary sarcoidosis vim lub ntsws fibrosis thiab infiltration.
Diagnosis:
TB tau kuaj pom los ntawm microbiological kev pom zoo los ntawm cov kua qaub nrawm, kab lis kev cai, thiab PCR.
Sarcoidosis yog kuaj los ntawm cov cim raug suav nrog nce qib angiotensin-hloov enzyme (ACE) thiab qib calcium,
Kev kho mob:
TB kho nrog kev kho tus kab mob.
Sarcoidosis kho nrog steroids thiab lwm yam tshuaj tiv thaiv kab mob.
Image Courtesy: 1. Tuberculosis Symptoms By Häggström, Mikael. "Medical gallery ntawm Mikael Häggström 2014". Wikiversity Journal of Medicine 1 (2). DOI: 10.15347/wm/2014.008. ISSN 20018762. [Public domain], via Wikimedia Commons 2. Sarcoidosis Los ntawm NHLBI cov kws sau ntawv. [Public domain], ntawm Wikimedia Commons