Qhov sib txawv tseem ceeb ntawm COP thiab clathrin coated vesicles yog tias COP coated vesicles yog thauj vesicles tsim los ntawm cytoplasmic coated proteins xws li coated protein I thiab II, thaum clathrin-coated vesicles yog thauj vesicles tsim los ntawm clathrin proteins txuas nrog lub membrane ntawm ib qho ntawm clathrin adapter complexes.
Kev thauj vesicles tuaj yeem txav cov molecules ntawm qhov chaw sib txawv ntawm tes. Piv txwv li, lawv tuaj yeem txav cov protein los ntawm qhov ntxhib endoplasmic reticulum mus rau Golgi apparatus. Proteins yog tsim los ntawm ribosomes pom nyob rau hauv qhov ntxhib endoplasmic reticulum. Tom qab ntawd cov proteins no paub tab hauv Golgi apparatus ua ntej lawv mus txog lawv qhov chaw kawg, xws li lysosomes, peroxisomes, lossis sab nraud ntawm tes. Cov proteins no yog thauj los ntawm kev thauj vesicles hauv lub cell. COP thiab clathrin-coated vesicles yog ob hom kev thauj vesicles.
COP Coated Vesicles yog dab tsi?
COP coated vesicles yog thauj cov vesicles tsim los ntawm cytoplasmic coat proteins xws li coated proteins I thiab II. Lawv raug tsim thaum lub membrane-coated pits invaginate thiab pinch tawm. Sab nrauv ntawm cov hlwv thauj khoom no yog them nrog lub lattice-zoo li lub network ntawm COP (coat protein complex) proteins. Lub tsho tiv no protein complex yog ob hom: COPI lossis COPII. COPI coated vesicles thauj cov molecules rov qab los ntawm cisternae ntawm Golgi apparatus mus rau ntxhib endoplasmic reticulum. Ntawm qhov tod tes, COPII coated vesicles thauj cov molecules los ntawm ntxhib endoplasmic reticulum mus rau Golgi apparatus.
Daim duab 01: COP Coated Vesicles
Ntxiv mus, COPI coated vesicles koom nrog cov qauv thauj rov qab thaum COPII coated vesicles koom nrog hauv cov qauv thauj anterograde. Cov vesicles thauj xws li COP coated vesicles yog qee zaum hu ua cargo-muaj cov hlab ntsha thiab lub tsho tiv no protein li cargo proteins. Cov vesicles ib txwm txav khoom los ntawm tus neeg pub khoom noj khoom haus mus rau tus neeg txais organelle. Tsis tas li ntawd, cov vesicles no tuaj yeem cuam tshuam thoob plaws lub cytoplasm lossis tuaj yeem ntes caij ntawm cytoskeleton kom txog thaum lawv mus txog qhov chaw tseeb.
Clathrin Coated Vesicles yog dab tsi?
Clathrin coated vesicles yog thauj vesicles uas yog tsim los ntawm clathrin protein txuas nrog rau daim nyias nyias ntawm ib qho ntawm clathrin adapter complexes. Clathrin yog cov protein uas ua lub luag haujlwm tseem ceeb hauv kev tsim cov hlwv coated. Clathrin protein tau pom thawj zaug thiab muaj npe los ntawm Barbara Pearse hauv xyoo 1976. Clathrin yog siv los tsim cov hlwv me me kom thauj cov molecules hauv hlwb.
Daim duab 02: Clathrin Coated Vesicles
Endocytosis thiab exocytosis ntawm cov vesicles no tso cai rau cov hlwb sib txuas lus, hloov cov khoom noj khoom haus, ntshuam cov cim receptors, kho lub cev tiv thaiv kab mob tom qab kuaj qhov chaw nyob sab nraud, thiab ntxuav cov cell khib nyiab los ntawm cov ntaub so ntswg. Tsis tas li ntawd, txoj kev endocytic tuaj yeem raug nyiag los ntawm cov kab mob thiab lwm yam kab mob txhawm rau txhawm rau nkag mus rau hauv lub cell thaum kis kab mob. Tsis tas li ntawd, clathrin-coated vesicles mediate endocytosis ntawm transmembrane receptors thiab thauj cov enzymes tshiab zoo li lysosomal hydrolases los ntawm trans-Golgi network mus rau lysosome.
Dab tsi yog qhov zoo sib xws ntawm COP thiab Clathrin Coated Vesicles?
- COP thiab clathrin-coated vesicles yog ob hom kev thauj mus los.
- Ob lub hlwv yog coated nrog cov proteins tshwj xeeb.
- Cov vesicles no pab thauj cov molecules tseem ceeb hauv cov hlwb.
- Ob lub hlwv tuaj yeem me me.
Qhov txawv ntawm COP thiab Clathrin Coated Vesicles yog dab tsi?
COP coated vesicles yog thauj vesicles tsim los ntawm cytoplasmic coat proteins xws li coated protein I thiab II, thaum clathrin-coated vesicles yog thauj vesicles tsim los ntawm clathrin proteins txuas nrog rau daim nyias nyias ntawm ib qho ntawm clathrin adapter complexes. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm COP thiab clathrin coated vesicles.
Cov hauv qab no qhia txog qhov sib txawv ntawm COP thiab clathrin coated vesicles hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – COP vs Clathrin Coated Vesicles
COP thiab clathrin-coated vesicles yog ob hom kev thauj mus los. COP coated vesicles yog tsim los ntawm cytoplasmic coat protein xws li coated protein I thiab II, thaum clathrin-coated vesicles yog tsim los ntawm clathrin protein txuas rau daim nyias nyias ntawm ib qho ntawm clathrin adapter complexes. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm COP thiab clathrin coated vesicles.
