Qhov sib txawv tseem ceeb ntawm ceramide thiab cerebroside yog tias ceramide yog ib qho lipid complex muaj li ntawm sphingosine thiab fatty acid, thaum cerebroside yog ib tug complex lipid muaj li ntawm sphingosine, fatty acid, thiab ib tug singular qab zib residue, uas yuav ua tau. Glucose los yog galactose.
Lipid yog macromolecule uas yog soluble hauv cov kuab tshuaj uas tsis yog-polar. Lub luag haujlwm ntawm lipids suav nrog khaws cia lub zog, teeb liab, thiab ua haujlwm raws li cov qauv hauv cov cell membranes. Ntxiv mus, lipids muaj ntau yam kev siv hauv kev lag luam tshuaj pleev ib ce, kev lag luam zaub mov, thiab nanotechnology. Lawv feem ntau muab faib ua ob pawg: yooj yim lipids thiab complex lipids. Ceramide thiab cerebroside yog ob hom sib txawv ntawm cov lipids.
YCeramide yog dab tsi?
Ceramide yog ib qho lipid complex uas muaj sphingosine thiab fatty acid. Feem ntau, ceramides yog tsev neeg ntawm waxy lipid molecules. Nws muaj nyob rau hauv siab concentrations nyob rau hauv lub cell membranes ntawm eukaryotic hlwb. Lawv yog cov khoom ntawm lipids uas ua rau sphingomyelin. Sphingomyelin yog ib qho ntawm cov lipids loj hauv lipid bilayer. Ntxiv mus, ceramides ua haujlwm sib txawv hauv lub cell. Lawv feem ntau txhawb cov qauv tsim. Tsis tas li ntawd, ceramides tuaj yeem koom nrog ntau yam ntawm cov xov tooj ntawm tes, suav nrog kev tswj kev sib txawv, kev loj hlob, thiab kev ua haujlwm ntawm tes tuag (PCD) ntawm cov hlwb.
Daim duab 01: Ceramide
Ceramide yog ib feem ntawm vernix caseosa. Vernix caseosa tseem hu ua yug custard. Nws yog cov khoom siv waxy dawb pom txheej ntawm daim tawv nqaij ntawm cov menyuam mos yug tshiab. Tsis tas li ntawd, muaj peb txoj hauv kev ntawm ceramide synthesis. Thawj txoj hauv kev yog txoj kev sphingomyelinase, qhov twg ib qho enzyme yog siv los rhuav tshem sphingomyelin hauv cov cell membrane. Txoj kev thib ob yog txoj kev de novo qhov twg ceramides yog tsim los ntawm cov molecules tsawg dua. Txoj kev thib peb yog txoj kev khaws cia uas sphingolipids tau tawg mus rau hauv sphingosine thiab tom qab ntawd rov qab siv dua los ntawm kev rov ua dua los ua cov tshuaj ceramide. Lub luag haujlwm rau ceramide thiab nws cov metabolites downstream kuj tau pom zoo hauv cov kab mob pathological xws li mob qog noj ntshav, neurodegeneration, ntshav qab zib, microbial pathogenesis, rog rog, thiab mob..
Cerebroside yog dab tsi?
Cerebroside yog ib qho lipid complex uas yog tsim los ntawm sphingosine, fatty acid, thiab ib qho qab zib residue, uas tuaj yeem yog cov piam thaj lossis galactose. Nws yog ib hom glycosphingolipid. Nws yog ib qho tseem ceeb ntawm cov tsiaj cov nqaij thiab cov paj hlwb. Raws li cov piam thaj residue, muaj ob hom cerebroside: glucocerebroside (muaj qabzib qab zib residue) thiab galactocerebroside (muaj galactose qab zib residue). Feem ntau, galactocerebroside muaj nyob rau hauv cov ntaub so ntswg neural, thaum glucocerebroside muaj nyob rau hauv lwm cov ntaub so ntswg.
Daim duab 02: Cerebroside
Cerebroside tsis muaj phosphoric acid. Kev sib sau ntau dhau ntawm cerebroside hauv tus po thiab lub siab ua rau muaj tus kab mob hu ua "Gaucher's disease." Gaucher tus kab mob yog tshwm sim los ntawm kev sib sau ntawm glucocerebroside. Tsis tas li ntawd, kev sib sau ntawm galactocerebroside ua rau cov kab mob xws li Fabry's kab mob thiab Krabbe's kab mob.
Dab tsi yog qhov zoo sib xws ntawm Ceramide thiab Cerebroside?
- Ceramide thiab cerebroside yog ob hom sib txawv ntawm cov lipids nyuaj.
- Ob leeg lipids muaj sphingosine thiab fatty acid.
- Cov lipids no tuaj yeem ua biosynthesized hauv tib neeg lub cev.
- Ob leeg lipids cuam tshuam nrog cov kab mob.
- Lawv tsis muaj phosphoric acid hauv cov qauv.
Qhov txawv ntawm Ceramide thiab Cerebroside yog dab tsi?
Ceramide yog ib qho lipid complex ua los ntawm sphingosine thiab fatty acid, thaum lub cerebroside yog ib tug complex lipid ua los ntawm sphingosine, ib tug fatty acid, thiab ib tug singular qab zib residue, uas yuav ua tau ib tug qabzib los yog galactose. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm ceramide thiab cerebroside. Tsis tas li ntawd, ceramide tsis yog glycosphingolipid, thaum cerebroside yog glycosphingolipid.
Cov hauv qab no qhia txog qhov sib txawv ntawm ceramide thiab cerebroside hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Ceramide vs Cerebroside
Ceramide thiab cerebroside yog ob hom sib txawv ntawm cov lipids nyuaj. Ceramide yog tsim los ntawm sphingosine thiab fatty acid, thaum lub cerebroside yog tsim los ntawm sphingosine, fatty acid, thiab ib qho lus qab zib residue, uas tuaj yeem yog cov piam thaj lossis galactose. Yog li, qhov no qhia txog qhov sib txawv ntawm ceramide thiab cerebroside.
