Qhov sib txawv tseem ceeb ntawm Corynebacterium diphtheriae thiab diphtheriae yog Corynebacterium diphtheriae muaj cov metachromatic granules nyob rau hauv cov cheeb tsam polar thaum diphtheroids tsis muaj metachromatic granules tab sis tau npaj ua palisade.
Corynebacterium yog ib hom kab mob gram-zoo thiab feem ntau aerobic. Lawv zoo li tus pas nrig, yog li lawv raug hu ua bacilli. Lawv dav nyob hauv qhov microbiota ntawm cov tsiaj thiab feem ntau tshwm sim hauv kev sib raug zoo nrog tus tswv tsev. Qee qhov muaj txiaj ntsig thiab tsis muaj kab mob, thaum qee qhov yog cov kab mob thiab ua rau muaj kab mob. Corynebacterium diphtheriae yog ib yam kab mob uas ua rau tus kab mob diphtheria. Diphtheroids xa mus rau ntau yam kab mob los ntawm cov genera ntawm Corynebacterium.
Corynebacterium Diphtheriae yog dab tsi?
Corynebacterium diphtheriae yog kab mob gram-zoo kab mob uas ua rau kab mob diphtheria. Nws yog ib tug pas nrig-puab, tsis-spore-forming, thiab tsis-motile kab mob. Muaj plaub hom kab mob no: C. diphtheriae mitis, C. diphtheriae intermedius, C. diphtheriae gravis, thiab C. diphtheriae belfanti. Lawv txawv me ntsis los ntawm lawv cov khoom biochemical thiab colony morphology. C. diphtheriae tsim cov kab mob diphtheria, uas hloov cov protein ua haujlwm hauv tus tswv tsev los ntawm inactivating elongation factor EF-2. Yog li ntawd, qhov no ua rau pharyngitis thiab pseudo-membrane hauv caj pas.
Daim duab 01: Corynebacterium diphtheria
A bacteriophage encodes cov noob lub luag hauj lwm rau diphtheria toxin thiab integrates nws mus rau hauv cov kab mob chromosome. Cov txheej txheem gram staining kom raug txheeb xyuas cov kab mob. Cov txheej txheem staining tshwj xeeb xws li Albert's stain thiab Ponder's stain qhia cov metachromatic granules uas tsim hauv cheeb tsam polar. Qhov nruab nrab enrichment hu ua Löffler qhov nruab nrab ua raws li qhov chaw zoo rau kev loj hlob ntawm C. diphtheriae. Lub phaj sib txawv hu ua tellurite agar tso cai rau cov kab mob kom txo tau tellurite rau metallic tellurium. Qhov no qhia tau hais tias xim av colonies rau feem ntau hom Corynebacterium tab sis tsim ib tug dub halo nyob ib ncig ntawm C. diphtheriae colonies. Elek's phaj kuaj yog ib qho kev kuaj hauv vitro los txiav txim siab qhov ua rau muaj kev phom sij lossis kev ua phem ntawm lub cev. Nws pab txheeb xyuas seb C. diphtheriae puas tuaj yeem tsim cov kab mob diphtheria toxin.
Dab tsi yog Diphtheroids?
Diphtheroids yog aerobic, non-spore-forming, pleomorphic gram-zoo kab mob suav nrog ntau yam kab mob los ntawm genera Corynebacterium. Lawv tsis muaj cov metachromatic granules tab sis tau npaj ua palisade. Diphtheroids yog commensals ntawm daim tawv nqaij thiab mucous daim nyias nyias. Yog li ntawd, lawv tshwm sim raws li cov kab mob sib kis thaum lub sij hawm kev cais tawm los ntawm kev kuaj mob.
Daim duab 02: Diphtheroids
Diphtheroids kuj muaj nyob rau hauv cov nroj tsuag, hauv av, hauv dej tshiab, thiab hauv dej ntsev. Txawm li cas los xij, diphtheroids cuam tshuam nrog ntau yam kab mob xws li kab mob sib kis los ntawm pseudo-membrane ntawm cov kab mob epithelial tuag thiab fibrin tsim nyob ib ncig ntawm tonsils thiab caj pas, kab mob hauv cov zis, kab mob ua pa, conjunctiva thiab nruab nrab pob ntseg, kab mob ntawm daim tawv nqaij, thiab ua rau mob hnyav. Cov kab mob xws li diphtheria, caseous lymphadenitis, granulomatous lymphadenopathy, pneumonitis, pharyngitis, thiab endocarditis. Diphtheroids kuj tawm tsam cov neeg mob immunocompromised. Ob peb piv txwv ntawm diphtheroids yog cutaneous diphtheroids thiab anaerobic diphtheroids, uas muaj nyob rau hauv cov cheeb tsam uas nplua nuj nyob rau hauv sebaceous qog. Cov txheej txheem staining gram pab txiav txim siab diphtheroids.
Dab tsi yog qhov zoo sib xws ntawm Corynebacterium Diphtheriae thiab Diphtheroids?
- Corynebacterium diphtheriae thiab diphtheria yog gram-positive.
- Lawv tsis sib xws, qwj zoo li, tsis-spore-forming, aerobic thiab tsis-motile.
- Ntxiv mus, lawv tuaj yeem txheeb xyuas tau los ntawm Gram Staining.
- Ob leeg tshwm sim hauv lub ntsws sab sauv.
- Lawv ua rau kab mob diphtheria.
Qhov txawv ntawm Corynebacterium diphtheriae thiab Diphtheriae yog dab tsi?
Corynebacterium diphtheriae muaj cov metachromatic granules nyob rau hauv cheeb tsam polar, thaum diphtheroids tsis muaj metachromatic granules, tab sis lawv tau teem rau hauv palisade yam. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm Corynebacterium Diphtheriae thiab diphtheroids. Tsis tas li ntawd, Corynebacterium diphtheria cuam tshuam rau lub ntsws sab sauv. Tab sis, diphtheroids cuam tshuam rau pseudo-membrane ntawm cov hlwb tuag epithelial. Thaum Corynebacterium diphtheria feem ntau ua rau kab mob Diphtheria, diphtheroids ua rau kab mob diphtheria, caseous lymphadenitis, granulomatous lymphadenopathy, pneumonitis, pharyngitis thiab endocarditis.
Cov duab hauv qab no nthuav tawm qhov sib txawv ntawm Corynebacterium Diphtheriae thiab diphtheriae hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Corynebacterium diphtheriae vs Diphtheria
Corynebacterium yog ib hom kab mob ntawm cov kab mob gram-zoo, feem ntau aerobic, tsis-motile, thiab qws-zoo li tus. Corynebacterium diphtheriae muaj metachromatic granules nyob rau hauv lub polar cheeb tsam, thaum diphtheroids tsis muaj metachromatic granules. Corynebacterium diphtheriae yog cov kab mob pathogenic uas ua rau kab mob diphtheria. Diphtheroids yog cov kab mob uas muaj nyob rau hauv ntau hom kab mob los ntawm genera Corynebacterium. Lawv muaj xws li cov kab mob pathogenic lossis cov kab mob uas tsis yog-pathogenic. Yog li, qhov no qhia txog qhov sib txawv ntawm Corynebacterium Diphtheriae thiab diphtheriae.
