Qhov sib txawv tseem ceeb ntawm kev ua kom tsis zoo thiab khi cov tshuaj tiv thaiv kab mob yog cov tshuaj tiv thaiv kab mob tsis zoo yog cov tshuaj tiv thaiv kab mob uas ua rau cov nyhuv antigen thaum khi cov tshuaj tiv thaiv yog cov tshuaj tiv thaiv kab mob uas khi nrog cov tshuaj tiv thaiv kab mob (tsis muaj kev cuam tshuam cov kab mob), tag, thiab ceeb toom kev tiv thaiv kab mob. cov hlwb hauv peb lub cev kom paub lawv.
Ib qho tshuaj tiv thaiv kab mob yog ib qho tshuaj tiv thaiv kab mob uas tsim los ntawm lub cev tiv thaiv kab mob ntawm peb lub cev txhawm rau txheeb xyuas thiab tshem tawm cov tshuaj tiv thaiv kab mob xws li kab mob, kab mob, thiab co toxins. Antigens yog txawv teb chaws invaders. Cov tshuaj tiv thaiv yog qhov tshwj xeeb, thiab lawv paub thiab khi nrog cov antigens tshwj xeeb. Lawv yog Y zoo li cov protein tiv thaiv. Lawv yog ib feem ntawm lub cev tiv thaiv kab mob. Neutralizing thiab binding antibodies yog ob hom tshuaj tiv thaiv. Neutralizing antibodies ncaj qha neutralize cov antigens. Kev khi cov tshuaj tiv thaiv kab mob khi nrog cov antigens thiab ceeb toom peb lub cev tiv thaiv kab mob kom pom muaj cov tshuaj tiv thaiv thiab rhuav tshem nws.
Neutralizing Antibodies yog dab tsi?
Neutralizing antibodies yog cov tshuaj tiv thaiv uas muaj peev xwm ua rau cov tshuaj tiv thaiv tsis zoo. Yog li, cov tshuaj tiv thaiv no tiv thaiv kev kis kab mob lossis kab mob muaj peev xwm ntawm antigens xws li kab mob thiab kab mob. Ntxiv mus, neutralizing cov tshuaj tiv thaiv tuaj yeem ua rau cov kab mob co toxins. Lawv tsis xav tau lub cev tiv thaiv kab mob los rhuav tshem cov antigens, tsis zoo li khi cov tshuaj tiv thaiv. Ua ntej kis rau cov hlwb, neutralizing antibodies rhuav tshem antigens nkag mus rau hauv lub cev. Txij li thaum neutralizing antibodies neutralize antigens ua ntej lawv kis rau peb lub hlwb, cov kev tiv thaiv tsim vim neutralizing antibodies hu ua sterilizing tiv thaiv kab mob.
Daim duab 01: Neutralizing Antibody
Neutralizing antibodies yog ib feem ntawm peb cov lus teb rau lub cev tiv thaiv kab mob. B hlwb nyob rau hauv cov pob txha pob txha tsim neutralizing antibodies los ntawm kev tiv thaiv kab mob. Neutralizing antibodies tseem ceeb heev tiv thaiv kab mob. Lawv tshwj xeeb khi nrog cov kab mob thiab thaiv lawv kom tsis txhob kis kab mob. Cov kab mob ua coated nrog neutralizing antibodies. Thaum lawv tau coated nrog cov tshuaj tiv thaiv kab mob, cov kab mob raug cuam tshuam los ntawm kev txuas mus rau lub hom phiaj ntawm tes lossis fusion nrog daim nyias nyias ntawm lub hom phiaj ntawm tes.
Dab tsi yog Binding Antibodies?
Kev khi cov tshuaj tiv thaiv yog ib hom tshuaj tiv thaiv kab mob uas khi nrog lawv cov antigens tshwj xeeb thiab ceeb toom peb lub cev tiv thaiv kab mob kom paub txog thiab rhuav tshem lawv. Kev khi cov tshuaj tiv thaiv tsis cuam tshuam nrog kev kis kab mob ntawm cov kab mob / antigen. Qhov tseeb, lawv tsis muaj peev xwm ntawm neutralizing antigens. Li no, lawv tseem hu ua non-neutralizing antibodies.
Daim duab 02: Cov qauv ntawm cov tshuaj tiv thaiv kab mob
Txhua lub neej, khi cov tshuaj tiv thaiv yog tsim los ntawm peb lub cev. Kev khi cov tshuaj tiv thaiv kab mob yog qhov muaj txiaj ntsig zoo raws li kev ntsuas kev kis kab mob.
Dab tsi zoo sib xws ntawm Neutralizing thiab Binding Antibodies?
- Neutralizing thiab binding antibodies yog ob hom tshuaj tiv thaiv.
- Lawv khi nrog cov tshuaj tiv thaiv tshwj xeeb.
- Lawv yog Y zoo li cov proteins.
- Lawv yog tsim los ntawm peb lub cev tiv thaiv kab mob.
- Lawv cov khoom tsim tawm los ntawm kev kis kab mob thiab tshuaj tiv thaiv.
Qhov txawv ntawm Neutralizing thiab Binding Antibodies yog dab tsi?
Neutralizing antibodies muaj peev xwm ntawm neutralizing antigens ua ntej antigens kis tus mob hlwb, thaum khi cov tshuaj tiv thaiv tsis muaj peev xwm ntawm neutralizing antigens; xwb, lawv tsho lawv thiab ceeb toom lub cev tiv thaiv kab mob kom puas lawv. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm neutralizing thiab binding antibodies. Ntxiv mus, neutralizing antibodies rhuav tshem cov antigens yam tsis muaj kev pab los ntawm lub cev tiv thaiv kab mob, thaum khi cov tshuaj tiv thaiv xav tau kev pab los ntawm lub cev tiv thaiv kab mob los rhuav tshem antigens.
Daim duab hauv qab no qhia qhov sib txawv ntawm qhov nruab nrab thiab khi cov tshuaj tiv thaiv kab mob hauv daim ntawv teev npe rau ib sab ntawm kev sib piv.
Summary – Neutralizing vs Binding Antibodies
Neutralizing antibodies thiab binding antibodies yog ob hom tshuaj tiv thaiv uas ua haujlwm tawm tsam antigens. Raws li lawv lub npe qhia, neutralizing antibodies neutralize tus kab mob los yog pathogenic kev ua si ntawm antigens yam tsis muaj kev pab los ntawm lwm yam kab mob. Nyob rau hauv sib piv, khi cov tshuaj tiv thaiv yog non-neutralizing antibodies uas khi rau antigens thiab ceeb toom peb lub cev tiv thaiv kab mob txog qhov muaj antigens. Yog li ntawd, khi cov tshuaj tiv thaiv kab mob tsis cuam tshuam nrog kev kis tus kab mob antigen. Lawv pab peb lub cev tiv thaiv kab mob hauv kev nrhiav cov kab mob tiv thaiv kab mob los tua cov antigens. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm nruab nrab thiab khi cov tshuaj tiv thaiv.