Qhov sib txawv tseem ceeb ntawm dihydropyridine thiab nondihydropyridine calcium channel blockers yog tias dihydropyridine calcium channel blockers ua los ntawm cov kab mob vascular vasodilation ntawm cov hlab ntsha, whereas non-dihydropyridine calcium channel blockers ua xaiv ntawm myocardium.
Calcium channel blockers lossis CCB yog ib pawg tshuaj uas tuaj yeem cuam tshuam kev txav ntawm calcium cations los ntawm calcium channels. Cov khoom no muaj txiaj ntsig zoo hauv cov tshuaj tiv thaiv hypertensive, xws li tshuaj siv los kho cov ntshav siab hauv cov neeg mob ntshav siab.
Dab tsi yog Dihydropyridine Calcium Channel Blockers?
Dihydropyridine calcium channel blockers yog cov molecules uas tau los ntawm dihydropyridine. Cov tshuaj no muaj txiaj ntsig zoo hauv kev txo cov kab mob vascular tsis kam thiab ntshav siab. Qee zaum peb tuaj yeem siv cov tshuaj no los kho angina. Peb kuj tuaj yeem siv nws los kho vasodilation thiab kub siab, uas tuaj yeem ua rau muaj kev cuam tshuam tachycardia. Cov mob no tuaj yeem ua rau muaj kev puas tsuaj rau cov neeg mob uas muaj cov tsos mob ischemic, uas tshwm sim los ntawm kev nce ntxiv hauv myocardial oxygen xav tau. Txawm li cas los xij, cov tshuaj no tuaj yeem ua rau cov proteinuria ua rau cov neeg mob uas muaj nephropathy.
Qee cov piv txwv rau dihydropyridine muaj xws li amlodipine, aranidipine, azelnidipine, barnidipine, benidipine, clevidipine, thiab lwm yam.
Nondihydropyridine Calcium Channel Blockers yog dab tsi?
Non-dihydropyridine calcium channel blockers yog cov molecules muab los ntawm phenylakylamine thiab benzothiazepine. Feem ntau, phenylakylamine calcium channel blockers feem ntau yog xaiv rau myocardium, thiab nws pab txo qis myocardial oxygen xav tau thiab thim rov qab vasospasm. Tsis tas li ntawd, peb tuaj yeem siv cov tshuaj no los kho angina. Piv nrog rau dihydropyridine calcium channel blockers, cov tshuaj no muaj cov teebmeem vasodilatory tsawg. Yog li ntawd, cov tshuaj no ua rau tsis tshua muaj reflex tachycardia. Qee qhov piv txwv ntawm phenylakylamine calcium channel blockers suav nrog fendiline, gallopamil, thiab verapamil.
Daim duab 01: Tus qauv ntawm Verapamil
Lwm hom nondihydropyridine calcium channel blocker yog tshuaj benzothiazepine. Cov tebchaw no yog nyob rau hauv chav kawm nruab nrab ntawm dihydropyridine tebchaw thiab phenylalkylamines, nyob ntawm seb qhov kev xaiv rau vascular calcium channels. Ntxiv nrog rau phenylakylamine thiab benzothiazepine, kuj tseem muaj lwm cov tshuaj uas tuaj yeem ua raws li nondihydropyridine calcium channel blockers.
Qhov txawv ntawm Dihydropyridine thiab Nondihydropyridine Calcium Channel Blockers
Calcium channel blockers lossis CCB yog ib pawg tshuaj uas tuaj yeem cuam tshuam kev txav ntawm calcium cations los ntawm calcium channels. Cov khoom no muaj txiaj ntsig zoo hauv cov tshuaj antihypertensive, xws li tshuaj siv los kho cov ntshav siab hauv cov neeg mob ntshav siab. Dihydropyridine calcium channel blockers yog cov molecules uas tau los ntawm dihydropyridine thaum nondihydropyridine calcium channel blockers yog cov molecules muab tau los ntawm phenylakylamine thiab benzothiazepine.
Qhov sib txawv tseem ceeb ntawm dihydropyridine thiab nondihydropyridine calcium channel blockers yog tias dihydropyridine calcium channel blockers ua los ntawm cov kab mob vascular vasodilation ntawm cov hlab ntsha, thaum nondihydropyridine calcium channel blockers ua xaiv ntawm myocardium. Tsis tas li ntawd, dihydropyridine calcium channel blockers muaj kev xaiv nruab nrab rau vascular calcium channels, whereas nondihydropyridine calcium channel blockers muaj nruab nrab rau qis qis rau vascular calcium channels. Ntxiv mus, cov piv txwv zoo rau dihydropyridine muaj xws li amlodipine, aranidipine, azelnidipine, barnidipine, benidipine, clevidipine, thiab lwm yam thaum qee qhov piv txwv ntawm phenylakylamine calcium channel blockers suav nrog fendiline, gallopamil, thiab verapamil.
Cov lus qhia hauv qab no qhia txog qhov sib txawv ntawm dihydropyridine thiab nondihydropyridine calcium channel blockers hauv daim ntawv tabular rau ib sab sib piv.
Summary – Dihydropyridine vs Nondihydropyridine Calcium Channel Blockers
Calcium channel blockers lossis CCB yog ib pawg tshuaj uas tuaj yeem cuam tshuam kev txav ntawm calcium cations los ntawm calcium channels. Qhov sib txawv tseem ceeb ntawm dihydropyridine thiab nondihydropyridine calcium channel blockers yog tias dihydropyridine calcium channel blockers ua los ntawm cov kab mob vascular vasodilation ntawm cov hlab ntsha, whereas nondihydropyridine calcium channel blockers ua xaiv ntawm myocardium..
