Qhov sib txawv tseem ceeb ntawm ib nrab thiab tsis meej asymmetric synthesis yog tias ib nrab asymmetric synthesis yog kev tsim cov chirality tsis zoo nyob rau hauv symmetrical molecules, whereas absolute asymmetric synthesis yog tsim cov nyiam chirality nyob rau hauv ib puag ncig symmetrical los ntawm symmetric reagent.
Asymmetric synthesis yog ib hom tshuaj synthesis uas muaj tshuaj lom neeg tshwm sim, tsim ib lossis ntau lub ntsiab lus tshiab ntawm chirality daim ntawv nyob rau hauv lub substrate molecule. Peb tuaj yeem pom lo lus no hauv ob hom ntawv ua ib nrab asymmetric synthesis thiab asymmetric synthesis kiag li. Txawm li cas los xij, lo lus ib nrab asymmetric synthesis tsis tshua siv hauv chemistry.
Asymmetric Synthesis yog dab tsi?
Asymmetric synthesis, tseem hu ua stereoselective synthesis, yog cov tshuaj tiv thaiv kab mob lossis cov tshuaj tiv thaiv kab mob uas ib lossis ntau lub ntsiab lus tshiab ntawm chirality tsim tau pom hauv ib qho tshwj xeeb substrate molecule. Qhov no ua rau stereoisomeric (tshwj xeeb yog enantiomeric lossis diastereoisomeric) cov khoom uas tsis sib npaug ntawm cov nyiaj. Txoj kev sib xyaw no yog qhov tseem ceeb hauv kev tsim cov khoom siv tshwj xeeb los ntawm achiral compounds lossis racemic mixtures. Muaj peb hom asymmetric synthesis: absolute synthesis, ib nrab asymmetric synthesis thiab enantio tshwj xeeb synthesis.
hom tshuaj tiv thaiv no yog tshwm sim los ntawm kev cuam tshuam los ntawm qee qhov kev tsis sib haum xeeb hauv cov txheej txheem reacting, xws li. lub xub ntiag ntawm ib tug dissymmetry chaw nyob rau hauv lub molecule, muaj ib tug dissymmetric hnyav hnyav los yog ib tug catalyst, muaj lub voj voog polarized lub teeb, thiab lwm yam. Feem ntau, peb muaj peev xwm faib cov asymmetric synthesis tshwm sim raws li stereoselective cov tshuaj tiv thaiv. Ntawm no, yog tias ib qho ntawm cov khoom tsim tshwj xeeb, ces peb hu cov tshuaj tiv thaiv stereospecific cov tshuaj tiv thaiv.
Ib nrab Asymmetric Synthesis yog dab tsi?
Ib nrab asymmetric synthesis yog tshuaj lom neeg cov tshuaj tiv thaiv uas cuam tshuam txog kev tsim cov chirality tsis zoo hauv cov molecules symmetrical. Lo lus no tsis tshua muaj siv nyob rau hauv chemistry vim hais tias hom tshuaj tiv thaiv no muaj tsawg dua qhov tseem ceeb piv rau asymmetric synthesis kiag li.
Daim duab 01: Chirality hauv daim duab yooj yim
Piv txwv li, rau ib feem asymmetric synthesis, peb tuaj yeem muab cov tshuaj tiv thaiv ntawm optically active styrene oxide nrog triethyl alpha-phosphonopropionate, uas muab 2-phenyl-1-methylcyclopropanecarboxylate, uas yog chiral. Cov khoom tshwm sim no muaj ib qhov chaw asymmetric uas yog los ntawm styrene oxide.
Dab tsi yog Asymmetric Synthesis?
Tsis muaj asymmetric synthesis yog tshuaj lom neeg cov tshuaj tiv thaiv uas suav nrog kev tsim cov kev nyiam chirality hauv ib puag ncig symmetrical los ntawm symmetric reagent. Piv txwv li, yog tias peb tuaj yeem npaj 2-hydroxypropanenitrile los ntawm ethanal thiab hydrogen cyanide thaum tsis muaj lwm yam chiral reagents, nws muab ntau tshaj ntawm ib qho enantiomer tshaj lwm tus.
Dab tsi yog qhov txawv ntawm Ib Feem thiab Tsis Txaus Siab Asymmetric Synthesis?
Cov ntsiab lus meej thiab ib nrab synthesis yog siv rau hauv asymmetric synthesis, qhov twg chirality yog tsim nyob rau hauv substrate molecules ntawm cov tshuaj tiv thaiv. Qhov sib txawv tseem ceeb ntawm ib nrab thiab tsis meej asymmetric synthesis yog tias ib nrab asymmetric synthesis yog kev tsim cov chirality tsis zoo nyob rau hauv symmetrical molecules, whereas absolute asymmetric synthesis yog tsim cov nyiam chirality nyob rau hauv ib puag ncig symmetrical los ntawm symmetric reagent.
Cov hauv qab no infographic teev qhov sib txawv ntawm ib nrab thiab asymmetric synthesis hauv daim ntawv tabular.
Summary - Ib nrab vs Tsis Txaus Siab Asymmetric Synthesis
Asymmetric synthesis yog ib hom tshuaj synthesis uas muaj tshuaj lom neeg tshwm sim los ua ib lossis ntau lub ntsiab lus tshiab ntawm chirality daim ntawv nyob rau hauv ib lub substrate molecule. Muaj ob hom asymmetric synthesis kiag li thiab ib nrab. Qhov sib txawv tseem ceeb ntawm ib nrab thiab tsis meej asymmetric synthesis yog tias ib nrab asymmetric synthesis yog kev tsim cov chirality tsis zoo nyob rau hauv symmetrical molecules whereas absolute asymmetric synthesis yog kev tsim cov kev nyiam chirality hauv ib puag ncig symmetrical los ntawm symmetric reagent.
