Qhov sib txawv tseem ceeb ntawm glycosylation thiab glycosidation yog glycosylation yog cov txheej txheem uas txuas cov carbohydrate rau cov protein lossis lipid molecule thaum glycosidation yog txheej txheem ntawm kev tsim glycoside.
Glycosylation thiab glycosidation yog ob txheej txheem tseem ceeb tshwm sim hauv cov kab mob nyob. Ob leeg glycosylation thiab glycosidation suav nrog qab zib lossis carbohydrates. Thaum lub sij hawm glycosylation, carbohydrates txuas nrog lwm cov organic molecules xws li cov proteins lossis lipids thaum glycosides tsim tshwm sim thaum glycosidation.
YGlycosylation yog dab tsi?
Glycosylation yog cov txheej txheem enzymatic uas txuas cov carbohydrate lossis glycan rau cov protein, lossis lwm cov organic molecules xws li lipids. Cov tshuaj tiv thaiv tshwm sim ntawm tus glycosyl pub dawb thiab glycosyl txais, thiab glycosyltransferases feem ntau ua rau cov tshuaj tiv thaiv ntawm lawv. Ntxiv mus, glycosylation yog cov txheej txheem tseem ceeb hauv cov proteins (protein glycosylation) kom lawv cov khoom ua haujlwm tau zoo; nws nce protein ntau ntau los yog cov proteome ib yam nkaus. Feem ntau ntawm cov proteins dhau glycosylation ntawm qhov ntxhib endoplasmic reticulum thiab dhau los ua glycoproteins. Glycosylation tshwj xeeb tshaj yog pab cov proteins kom raug. Tsis tas li ntawd, glycosylation ua rau cov protein ruaj khov thaum txuas nrog oligosaccharides thiab pab txhawb kev taw qhia thiab cov xovtooj ntawm tes mus rau lub cell adhesion.
Daim duab 01: N-txuas Protein Glycosylation
Tsis tas li ntawd, glycosylation yog hom kev hloov pauv tom qab kev hloov pauv uas tshwm sim hauv cov protein. Nws suav nrog ntau cov kauj ruam enzymatic. N-linked glycosylation, O -linked glycosylation, phosphoserine glycosylation, C -mannosylation thiab glypiation yog ob peb hom glycosylations. Tsis tas li ntawd, qhov rov qab cov tshuaj tiv thaiv ntawm glycosylation yog deglycosylation. Yog li, deglycosylation yog hais txog cov tshuaj tiv thaiv enzymatic ntawm tshem glycans los ntawm cov proteins.
YGlycosidation yog dab tsi?
Glycosidation yog tsim ntawm glycosides. Glycosides yog ntau yam ntawm cov khoom tshwm sim. Muaj ib feem carbohydrate ua ke nrog hydroxyl compound ntawm glycosidic daim ntawv cog lus hauv glycoside. Nws yog covalent daim ntawv cog lus. Yog li, ib yam khoom uas muaj glycosidic daim ntawv cog lus yog glycoside, thiab glycosidation yog txheej txheem tsim ntawm glycosides.
Daim duab 02: Glycosidation
Qhov tseeb, glycosidation yog hom kev hloov pauv ntawm cov piam thaj molecules. Tshem tawm aldehyde lossis ketone pawg yog ib txoj hauv kev ntawm glycosidation. Yog li, qhov no tuaj yeem ua tau los ntawm kev ua rau cov piam thaj nrog cawv lossis amines.
Dab tsi zoo sib xws ntawm Glycosylation thiab Glycosidation?
- Nyob rau hauv ob txoj kev, ib tug carbohydrate molecule nyob rau hauv ib qho kev cuam tshuam nrog lwm molecule.
- Ob leeg yog cov txheej txheem biochemical tseem ceeb tshwm sim hauv cov kab mob nyob.
Qhov txawv ntawm Glycosylation thiab Glycosidation yog dab tsi?
Glycosylation hloov cov carbohydrate mus rau glycoprotein lossis glycolipid thaum glycosidation hloov cov carbohydrate mus rau glycoside. Yog li, glycosylation yog cov tshuaj tiv thaiv enzymatic uas txuas cov carbohydrate nrog lwm cov organic compound xws li protein lossis lipid. Ntawm qhov tod tes, glycosidation yog tsim los ntawm glycoside los ntawm kev tsim ib daim ntawv cog lus glycosidic. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm glycosylation thiab glycosidation.
Summary - Glycosylation vs Glycosidation
Hauv kev xaus qhov sib txawv ntawm glycosylation thiab glycosidation, glycosylation yog cov txheej txheem enzymatic uas txuas cov carbohydrate lossis glycan rau cov protein, lossis lwm cov organic molecules xws li lipids. Glycosidation yog cov txheej txheem uas tsim glycosides los ntawm kev tsim glycosidic daim ntawv cog lus ntawm carbohydrate thiab hydroxyl compound, tshwj xeeb tshaj yog nrog cawv lossis amines.
