Qhov sib txawv tseem ceeb ntawm histamine thiab antihistamine yog tias cov tshuaj histamine tuaj yeem ua rau muaj kev tsis haum tshuaj thaum cov tshuaj tiv thaiv kab mob tuaj yeem thaiv cov tshuaj tiv thaiv histamine thiab ua kom peb lub cev.
Peb lub cev tsim cov tshuaj sib txawv xws li neurotransmitters, cov tshuaj hormones, enzymes, thiab lwm yam. Histamine thiab antihistamine yog ob qho tseem ceeb tshuaj xa xov. Lawv tuaj yeem raug tsim los ntawm peb lub cev thiab tuaj yeem qhia tawm sab nraud thaum xav tau. Txawm li cas los xij, lawv cov haujlwm yog qhov sib txawv. Histamine ua rau muaj kev tsis haum tshuaj thaum antihistamine txo cov kev tsis haum tshuaj. Ob qho tshuaj no sib tw thiab khi nrog tib receptors. Yog li, ib qho tshuaj tiv thaiv kab mob tuaj yeem thaiv kev khi ntawm histamine rau receptors thiab tiv thaiv nws qhov kev ua.
Histamine yog dab tsi?
Histamine yog ib qho amine uas ua rau muaj kev tsis haum tshuaj thaum nws ntsib cov tshuaj benign hauv lub cev. Peb lub cev tsim cov tshuaj histamines los ntawm cov amino acid histidine. Histamine ntau lawm tshwm sim nyob rau hauv granules ntawm mast hlwb thiab basophils. Thaum lub cev xav tau cov tshuaj histamine ntxiv, nws tuaj yeem qhia los ntawm cov chaw sab nraud ib yam nkaus.
Apart from triggering allergic reactions, histamine ua haujlwm ntau lub cev ua haujlwm ib yam nkaus. Histamine tuaj yeem ua rau peb lub cev tiv thaiv kab mob. Nws ua rau khaus, thiab nws ceeb toom cov qe ntshav dawb rau kev hem thawj ntawm txawv teb chaws antigens. Tsis tas li ntawd, histamine txhawb nqa cov leeg nqaij du thiab ua rau lub plab acid secretion. Thiab tseem, nws nce vascular permeability, cell proliferation, o, immunomodulation, thiab lwm yam.
Daim duab 01: Histamine
Yuav kom ua tiav cov haujlwm histamine, nws yuav tsum khi rau tus neeg txais khoom. Muaj plaub G protein-coupled histamine binding receptors. Namely, lawv yog H1, H2, H3, thiab H4 receptors. H1 thiab H2 receptors nyob thoob plaws lub cev; tshwj xeeb tshaj yog nyob rau hauv cov nqaij du, endothelium thiab gastric mucosa. Tab sis, H3 yog presynaptic, thiab H4 yog haematopoietic. H3 receptors feem ntau pom nyob rau hauv cov hlab ntsha hauv plab thaum H4 receptors feem ntau nrhiav ntawm cov qe ntshav dawb.
Antihistamine yog dab tsi?
Antihistamine yog ib yam tshuaj uas kho cov tsos mob ua xua xws li txham, dej qhov muag, khaus khaus, thiab qhov ntswg. Antihistamine sib tw nrog histamine rau histamine receptors los ntawm kev ua raws li histamine antagonist, thiab yog li, thaiv cov tshuaj tiv thaiv histamine. Tsis tas li ntawd, antihistamine ua haujlwm los ntawm kev txo cov histamine-receptor kev ua haujlwm ntawm cov hlab ntsha, vascular du nqaij, glandular cells, endothelium, thiab mast hlwb los tiv thaiv histamine ua. Tsis tas li, cov tshuaj tiv thaiv kab mob tuaj yeem yog H1-antihistamines, H2-antihistamines, H3-antihistamines lossis H4 antihistamines. Qhov kev faib tawm no qhia peb tias dab tsi yog qhov histamine receptor nws thaiv?. Ua piv txwv, H1-antihistamines tiv thaiv kev khi ntawm histamine nrog H1 receptors.
Daim duab 02: Antihistamine
Tsis tas li ntawd, cov tshuaj antihistamine muaj nyob rau hauv cov ntawv tshuaj ntsiav, ntsiav tshuaj, kua, tee, tshuaj, thiab tshuaj tsuag qhov ntswg. Cov tshuaj no tuaj yeem ua rau muaj kev phiv xws li qaug zog, qhov ncauj qhuav, kiv taub hau, mob taub hau, mob plab, qhov muag tsis pom kev, thiab lwm yam.
Dab tsi zoo sib xws ntawm Histamine thiab Antihistamine?
- Histamine thiab Antihistamine yog tshuaj xa xov.
- Lawv sib tw rau tib tus txais.
- Tsis tas li ntawd, tib neeg lub cev muaj peev xwm ua tau ob qho tshuaj.
- Tsis tas li ntawd, lawv tuaj yeem nkag mus rau hauv peb lub cev los ntawm sab nraud.
- Ob leeg tsim nyog rau ntau lub luag haujlwm hauv lub cev.
- Tsis tas li ntawd, ob qho tshuaj no nquag koom nrog peb lub voj voog pw tsaug zog.
Qhov txawv ntawm Histamine thiab Antihistamine yog dab tsi?
Histamine thiab tshuaj tiv thaiv kab mob yog ob lub ntsiab lus tseem ceeb uas kho ntau lub luag haujlwm hauv peb lub cev. Antihistamine ua qhov cuam tshuam ntawm histamine. Thaum histamine tsim kev tsis haum tshuaj, cov tshuaj antihistamine txo cov kev tsis haum tshuaj. Qhov no yog qhov sib txawv tseem ceeb ntawm histamine thiab antihistamine. Lwm qhov sib txawv ntawm histamine thiab antihistamine yog tias cov tshuaj histamine yog lub luag haujlwm rau kev pw tsaug zog thaum cov tshuaj tiv thaiv kab mob ua rau qaug zog. Histamine kuj yog lub luag haujlwm rau kev tso kua qaub hauv plab, ua kom cov leeg nqaij du, khaus, thiab lwm yam. Ob leeg histamine thiab antihistamine sib tw rau tib hom receptors. Qhov no yog cov txheej txheem uas cov tshuaj tiv thaiv kab mob siv los thaiv cov tshuaj histamine.
Summary – Histamine vs Antihistamine
Histamine yog cov tshuaj xa xov lossis cov tshuaj neurotransmitter uas ua rau cov tsos mob ua xua, khaus khaus thiab lwm yam. Tag nrho cov tshuaj histamine pib thaum histamine khi nrog nws cov receptors. Muaj plaub histamine receptors. Thaum muaj kev fab tshuaj, peb nyiam noj tshuaj. Cov tshuaj no feem ntau yog cov tshuaj tiv thaiv kab mob uas ua haujlwm tawm tsam histamines. Antihistamines tiv thaiv kev khi ntawm histamine nrog receptors lossis los ntawm kev txo cov haujlwm ntawm histamine-receptors. Qhov no yog qhov txawv ntawm histamine thiab antihistamine.
