Qhov sib txawv tseem ceeb ntawm caseating thiab noncaseating granulomas yog tias caseating granuloma muaj xim dawb, cheese zoo li cov khib nyiab ntawm qhov chaw uas tsis muaj kab mob granuloma tsis muaj qhov chaw zoo li no uas tau mob necrosis.
Granulomatous o yog ib qho ntawm cov lus teb mob ntev uas peb lub cev sim tiv thaiv kev kis tus kab mob uas nws tsis tuaj yeem tshem tawm. Ib qho granuloma uas nws qhov chaw tau dhau los ntawm caseous necrosis hu ua caseating granuloma. Ib qho noncaseating granuloma, ntawm qhov tod tes, yog granuloma uas tsis muaj lub hauv paus caseating necrosis.
Dab tsi yog Granuloma?
Granulomatous o yog ib hom mob ntev uas pab lub cev kom muaj cov kab mob sib kis. Muaj kev ua kom dav dav ntawm T lymphocytes hauv qhov xwm txheej no, uas, dhau los, ua rau kev ua kom cov macrophages. Macrophages tau txais ntau ntawm cytoplasm hauv cov txheej txheem no thiab yog li pib zoo li cov hlwb epithelial. Yog li ntawd, cov macrophages loj nyob rau hauv granuloma yog hu ua epitheliod hlwb. Tsis tas li ntawd, kev sib xyaw ntawm cov hlwb no tsim cov hlwb loj heev.
YKev faib tawm ntawm Granulomas
Nyob ntawm cov kab mob, muaj ob pawg ntawm granulomas; uas yog immune granuloma thiab txawv teb chaws lub cev granuloma.
Txawv teb chaws lub cev granuloma feem ntau tsim nyob ib ncig ntawm cov ntaub ntawv suture thiab talc. Cov ntaub ntawv no tsis ua rau cov txheej txheem inflammatory, tab sis lawv qhib cov phagocytosis los ntawm macrophages. Macrophages thiab epitheliod hlwb nyob ib ncig ntawm lub cev txawv teb chaws uas yog nyob rau hauv nruab nrab ntawm lub granuloma.
Cov kab mob sib kis, uas muaj peev xwm ua rau T cell-mediated immune teb, ua rau cov kab mob ntawm cov kab mob granulomas. Ua ntej, macrophages tau qhib; Tom qab ntawd lawv qhib T cells. Cov activated T hlwb ces tso cytokines xws li IL2 thiab IFN, uas nyob rau hauv lem, qhib lwm T hlwb thiab macrophages, feem.
YCasating Granuloma yog dab tsi?
Thaum qee yam kab mob kis tau los ntawm kev tsim cov granuloma, thaj tsam hauv nruab nrab ntawm granuloma raug mob vim yog hypoxia thiab kev ua haujlwm dawb radical. Cov ntaub ntawv necrotic nyob rau hauv qhov chaw muaj ib tug cheesy dawb tsos. Caseating granuloma yog ib qho granuloma nrog rau qhov chaw uas tau dhau los ntawm caseous necrosis.
Daim duab 01: Caseating Granuloma hauv Tuberculosis
Nyob rau hauv lub microscope, cov ntaub so ntswg necrotic tshwm sim li dawb amorphous pawg uas tau plam tag nrho lawv cov cellular architecture. Caseating granulomas yog ib qho cim tshwj xeeb ntawm tuberculosis.
Noncaseating Granuloma yog dab tsi?
Noncaseating granuloma yog hais txog tag nrho cov granulomas uas tsis muaj qhov chaw uas tau dhau los ntawm caseating necrosis. Muab hauv qab no yog ib daim duab microscopic ntawm noncaseating granuloma.
Daim duab 02: Microscopic tshwm sim ntawm Noncaseating Granuloma
Noncaseating granuloma tshwm nyob rau hauv cov mob xws li sarcoidosis, mob ruas, thiab Crohn tus kab mob.
Similarities Ntawm Caseating thiab Noncaseating Granuloma
Kev tsim ntawm granuloma tshwm sim hauv ob qho tib si raws li cov lus teb rau tus neeg mob sab hauv lossis sab nraud
Qhov txawv ntawm Caseating thiab Noncaseating Granuloma
Caseating vs Noncaseating Granuloma |
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| Caseating granuloma yog ib qho granuloma nrog lub chaw uas tau dhau los ntawm caseous necrosis. | Noncaseating granuloma yog hais txog tag nrho cov granulomas uas tsis muaj lub chaw zoo li no uas tau dhau los ua tus kab mob necrosis. |
| Nws tshwm sim feem ntau hauv tuberculosis. | Nws tshwm sim hauv cov kab mob xws li sarcoidosis, Crohn tus kab mob, thiab mob ruas. |
Summary – Caseating vs Noncaseating Granuloma
A caseating granuloma is a granuloma with a center that has undergone caseous necrosis. Noncaseating granulomas muaj xws li tag nrho cov granulomas uas tsis muaj ib lub chaw uas tau undergone caseating necrosis. Yog li ntawd, qhov sib txawv tseem ceeb ntawm caseating thiab noncaseating granuloma yog tias cov noncaseating granulomas tsis muaj qhov chaw necrotic thaum caseating granulomas ua.
