Qhov Tseem Ceeb Qhov txawv - Klinefelter vs Turner Syndrome
Klinefelter syndrome yog txhais tias yog txiv neej hypogonadism uas tshwm sim thaum muaj ob lossis ntau dua X chromosomes thiab ob lossis ntau dua Y chromosomes. Turner Syndrome yog qhov ua tiav lossis ib nrab monosomy ntawm X chromosome, uas yog tus cwj pwm feem ntau los ntawm hypogonadism hauv phenotypic poj niam. Txij li feem ntau muaj ib qho chromosome ntxiv hauv Klinefelter syndrome, nws raug suav tias yog trisomy thaum tuner syndrome raug suav tias yog monosomy vim tias ib qho chromosome ploj lawm hauv cov tib neeg cuam tshuam. Qhov no yog qhov sib txawv tseem ceeb ntawm Klinefelter thiab Turner Syndrome.
Klinefelter Syndrome yog dab tsi?
Klinefelter syndrome yog txhais tias yog txiv neej hypogonadism uas tshwm sim thaum muaj ob lossis ntau dua X chromosomes thiab ob lossis ntau dua Y chromosomes. Tus mob no feem ntau raug kuaj pom tom qab yug me nyuam vim qhov txawv txav ntawm cov qog nqaij hlav tsis tshwm sim ua ntej thaum ntxov.
Kev Kho Mob Ntog Ntawm Klinefelter Syndrome
- me me atrophic testes thiab me noov
- Hypogonadism - Plasma gonadotropin concentration (tshwj xeeb tshaj yog FSH concentration) nce siab. Testosterone qib tau txo qis, tab sis qhov nruab nrab estradiol qib siab dua li qib ib txwm
- Ntsia elongated ob txhais ceg
- Tsis muaj txiv neej tus yam ntxwv sib deev
- Gynaecomastia
- Tsis muaj kev puas hlwb tab sis IQ tsawg dua li cov pej xeem ib txwm
- Ntau qhov tshwm sim ntawm hom II mob ntshav qab zib thiab metabolic syndrome
- Kev mob osteoporosis thiab pob txha fractures
- Txo cov spermatogenesis thiab txiv neej infertility
Cov neeg mob uas muaj tus mob Klinefelter muaj kev pheej hmoo ntau dua ntawm kev mob qog noj ntshav ntawm lub mis, kab mob extragonadal cell hlav thiab kab mob autoimmune xws li SLE.
Daim duab 01: 47, XXY Karyotype
Raws li tau hais dhau los, feem ntau ntawm cov mob Klinefelter syndrome yog txuam nrog 47, XXY karyotype. Qhov no yog vim tsis muaj kev sib cais thaum lub sij hawm meiotic faib cov kab mob ntawm ib tug niam txiv.
YTurner Syndrome yog dab tsi?
Turner syndrome yog qhov ua tiav lossis ib nrab ntawm monosomy ntawm X chromosome uas yog tus cwj pwm los ntawm hypogonadism hauv cov poj niam phenotypic. Lub karyotype feem ntau cuam tshuam nrog Turner syndrome yog 45, X. Qhov no yog vim tsis muaj tag nrho X chromosome, kev puas tsuaj rau X chromosomes lossis muaj cov mosaics.
Kev kho mob ntawm Turner Syndrome
- Cov tib neeg muaj kev cuam tshuam loj heev raug kev txom nyem los ntawm edema ntawm dorsum ntawm tes thiab ko taw thaum tseem me nyuam mos
- o ntawm caj dab caj dab kuj tuaj yeem pom qee zaus hauv cov menyuam mos uas cuam tshuam
- ob lub caj dab webbing
- Short stature
- dav hauv siab thiab dav dav lub txiv mis
- Coarctation ntawm aorta
- Txoj zes qe menyuam, tsis muaj menyuam, thiab amenorrhea
- Pigmented nevi
Daim duab 02: 45, X Karyotype
Dab tsi yog qhov zoo sib xws ntawm Klinefelter thiab Turner Syndrome?
Ob qho xwm txheej no yog cov kab mob cytogenic cuam tshuam nrog kev sib deev chromosomes
Qhov txawv ntawm Klinefelter thiab Turner Syndrome yog dab tsi?
Klinefelter Syndrome vs Turner Syndrome |
|
| Klinefelter syndrome yog txhais tias yog txiv neej hypogonadism uas tshwm sim thaum muaj ob lossis ntau X chromosomes thiab ob lossis ntau Y chromosomes. | Turner syndrome yog qhov ua tiav lossis ib nrab monosomy ntawm X chromosome uas yog tus cwj pwm feem ntau los ntawm hypogonadism hauv cov poj niam phenotypic. |
| Karyotype | |
| Klinefelter syndrome yog ib qho trisomy, thiab feem ntau txuam nrog karyotype yog 47, XXY. | Turner syndrome yog ib qho monosomy, thiab feem ntau nws cuam tshuam nrog karyotype 45, X. |
| Txiv neej muaj kev cuam tshuam | |
| Klinefelter syndrome ua rau txiv neej hypogonadism. | Turner syndrome ua rau poj niam hypogonadism. Txhais |
Summary – Klinefelter vs Turner Syndrome
Ob yam kab mob caj ces sib tham ntawm no yog cov mob tshwm sim heev. Qhov sib txawv tseem ceeb ntawm Klinefelter thiab Turner Syndrome yog Klinefelter syndrome yog trisomy thaum Turner syndrome yog monosomy. Kev kuaj mob ntxov ntawm lawv tuaj yeem pab kho cov teeb meem tshwm sim los ntawm tus kab mob hauv qab.
Image Courtesy:
1. "Human chromosomesXXY01" Los ntawm Tus Neeg Siv: Nami-ja - Tus kheej ua haujlwm (Public Domain) ntawm Commons Wikimedia
2. “45, X” (CC BY-SA 3.0) via Commons Wikimedia
