Synapse vs Synaptic Cleft
Nervous system yog ib qho kev sib sau ntawm cov cellular circuits uas tso cai rau tus tsiaj ua tej yam tseem ceeb rau kev ciaj sia. Cov kab hluav taws xob no yog tsim los ntawm cov hlwb tshwj xeeb hu ua neurons, uas xav tau los xa cov hluav taws xob thiab tshuaj lom neeg cov cim, cov txheej txheem kev nkag siab, pib cov lus teb rau tus cwj pwm, thiab tswj lub cev sab hauv ntawm cov kab mob. Cov txheej txheem ntawm kev sib txuas lus ntawm neurons yog hu ua synaptic kis tau tus mob. Synapses thiab synaptic cleft pab ua kev sib txuas ntawm cov neurons, yog li txhim khu kev sib kis ntawm cellular circuits.
Synapse
Synapse yog qhov chaw tshwj xeeb intercellular qhov chaw ceev, muaj kev sib kis ntawm cov tshuaj lom neeg thiab hluav taws xob tuaj yeem tshwm sim. Txawm hais tias feem ntau ntawm cov synapses nyob rau hauv lub hlwb mammalian yog tshuaj, synaptic kis tau tus mob yog tshuaj los yog hluav taws xob. Ntawm cov tshuaj synapses, neurotransmitter molecules raug tso tawm los ntawm lub davhlau ya nyob twg pre-synaptic mus rau hauv lub synaptic cleft. Cov molecules tom qab ntawd diffuse thiab khi rau qhov chaw lees paub ntawm lub hom phiaj receptors ntawm post synaptic membrane. Cov tshuaj synaptic kis tau sai, qhov chaw tshwj xeeb, thiab cov yas zoo heev.
Ntawm hluav taws xob synapses, ionotropic transmembrane raws ntawm cov plasma membrane tso cai ions thiab me me molecules xws li ATP, Ca2+, thiab IP3 hla ntawm cov neurons. Morphologically, synaptic junctions zoo li nruj junctions nrog cov plasma daim nyias nyias uas yog coated intercellular electrons. Txawm li cas los xij, synapses txawv ntawm lwm cov kev sib tshuam hauv qhov uas lawv muaj polarized heev. Peb yam ntxwv ntawm lub hauv paus synapses yog pre-synaptic paj terminals uas muaj cov neurotransmitter-filled vesicles, post-synaptic membrane tshwj xeeb uas muaj pawg neurotransmitter receptors, thiab synaptic cleft.
Synaptic Cleft
Lub synaptic cleft yog nqaim extracellular gap (kwv yees 20 mus rau 50 nm) uas cais cov pre thiab post synaptic membranes. Raws li lub hauv paus ntsiab lus ntawm synapse, synaptic cleft ua ob qho tib si mechanical thiab signaling functions. Mechanical functions yog kom stabilize lub parallel orientations ntawm lub pre thiab post-synaptic plasma daim nyias nyias, txuas cov membranes rau ib leeg ntawm ib tug sib nrug deb, thiab tswj lawv cov txheeb ze txoj hauj lwm. Synaptic cleft yog qhov chaw uas cov neurotransmitters ua. Nws kuj tseem kho kom haum xeeb tsis yog-transmitter signals ntawm pre-thiab post synaptic specializations.
Dab tsi yog qhov txawv ntawm Synapse thiab Synaptic Cleft?
• Synapse yog qhov chaw tshwj xeeb ntawm ob lub neurons, whereas synaptic cleft raug xa mus rau qhov sib txawv nqaim ntawm ncej thiab pre synaptic membranes.
• Synapse muaj peb yam xws li lub davhlau ya nyob twg pre-synaptic, post-synaptic davhlau ya nyob twg, thiab synaptic cleft.
• Synaptic cleft yog ib feem ntawm synapse.
