Qhov sib txawv tseem ceeb ntawm alpha beta gamma thiab delta coronavirus yog alpha thiab beta coronavirus feem ntau cuam tshuam nrog kev kis kab mob hauv cov tsiaj txhu thaum gamma thiab delta coronavirus feem ntau kis rau cov noog.
Coronaviruses yog cov kab mob uas muaj cov kab mob zoo-sensitive ib leeg-stranded RNA genome. Lawv muaj cov yam ntxwv zoo li lub club-zoo li lossis crown-zoo li spikes ntawm lawv qhov chaw. Ntxiv mus, lawv muaj ib tug tshwj xeeb replication mechanism thiab ib tug txawv txawv loj genome. Lawv kis tau ntau yam tsiaj xws li tsiaj txhu, noog, npua, nyuj thiab tib neeg. Yog li ntawd, lawv yog cov kab mob zoonotic. Lawv ua rau mob me mus rau qhov ua pa hnyav. Kev kis tus kabmob coronavirus los ntawm ib tus neeg mus rau lwm tus yuav tshwm sim los ntawm cov tee ua pa thiab kev sib cuag nrog tus neeg mob. Muaj plaub hom kab mob coronaviruses. Lawv yog Alphacoronavirus, Betacoronavirus, Gammacorornavirus thiab Deltacoronavirus.
Alpha Coronavirus yog dab tsi?
Alphacoronavirus yog ib hom kab mob coronaviruses. Lawv yog cov kab mob uas muaj kab mob uas muaj kab mob uas muaj txog 120 nm inch. Lawv muaj genome uas muaj liner ssRNA(+) ntawm 27 - 32 kb loj.
Daim duab 01: Tib neeg Coronaviruses
HCoV-NL63 thiab HCoV-229E yog ob tus tib neeg alphacoronaviruses uas yog lub luag haujlwm rau tus mob khaub thuas rau tib neeg thoob ntiaj teb. Alphacoronavisus yog muab los ntawm tus puav gene pas.
Beta Coronavirus yog dab tsi?
Betacoronavirus yog lwm hom kab mob coronaviruses uas kis tau rau tib neeg. SARS-CoV, MERS-CoV, and some HCoVs, including HCoV-OC43 and HCoV-HKU1, belong to this genus. SARS-CoV ua rau mob hnyav ua pa nyuaj lossis SARS. SARS-CoV2 yog betacoronavirus uas yog lub luag haujlwm rau kev kis thoob ntiaj teb tam sim no ntawm COVID 19. MERS-CoV ua rau Middle East Respiratory Syndrome lossis MERS.
Figure 02: Betacoronavirus – SARS-CoV2
Muaj ntau tus kabmob coronaviruses, suav nrog SARS-CoV thiab MERS-CoV yog muab los ntawm puav. Lawv yog lub ntuj reservoir ntawm betacoronaviruses. Lawv kis tau ntau tus kabmob coronaviruses ntawm cov tsiaj thiab tib neeg.
Gamma Coronavirus yog dab tsi?
Gammacoronavirus yog lwm hom kab mob coronaviruses. Cov pab pawg no tseem hu ua kab mob coronavirus pawg 3. Lawv feem ntau yog avian coronaviruses zoo ib yam li deltacoronavirus. Gammacoronaviruses yog cov kab mob uas muaj cov kab mob uas muaj qhov ntev ntawm 120 nm. Lawv RNA genome yog txuam nrog N proteins rau cov nucleocapsid. Avian kis kab mob bronchitis tus kab mob yog gammacoronavirus, thiab nws muaj monopartite, linear ssRNA(+) genome ntawm 27-32 kb loj.
Delta Coronavirus yog dab tsi?
Deltacoronavirus yog plaub hom kab mob coronaviruses. Lawv muab tau los ntawm avian gene pas dej thiab kuj los ntawm npua. Porcine Deltacoronavirus los yog PDCoV muaj cov kab mob loj ntawm 25.4 kb. Ib qho kev sib koom ua ke yog ib qho xwm txheej nquag pom hauv deltacoronaviruses. Li no, nws yog ib qho kev pheej hmoo ua rau muaj tus kab mob tshiab uas muaj peev xwm kis tau tus kab mob sib kis thiab hloov mus rau cov tswv tsev tshiab.
Dab tsi yog qhov zoo sib xws ntawm Alpha Beta Gamma thiab Delta Coronavirus?
- Alpha, beta, gamma thiab delta coronavirus yog plaub hom kab mob coronaviruses.
- Lawv yog cov kab mob zoonotic.
- Lawv txhua tus muaj raws li kev txiav txim: Nidovirales, tsev neeg: Coronaviridae thiab subfamily: Orthocoronavirinae.
- Lawv yog cov kab mob hauv hnab.
- Lawv cov genomes yog qhov loj tshaj ntawm cov kab mob RNA.
- Ntxiv mus, lawv muaj ib leeg-stranded zoo-sensitive RNA genome.
- Lawv tsis yog ntu, 5'capped, thiab 3' polyadenylated.
- Tsis tas li ntawd, lawv muaj tsawg kawg yog plaub tus qauv canonical proteins; E (lub hnab ntawv protein), M (membrane protein), N (nucleocapsid protein), thiab S (spike protein).
Qhov txawv ntawm Alpha Beta Gamma thiab Delta Coronavirus yog dab tsi?
Alpha thiab Betacoronaviruses kis tau tsiaj rau tsiaj thaum Gamma thiab Deltacoronaviruses feem ntau kis rau noog. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm alpha beta gamma thiab delta coronavirus.
Hauv qab infographic qhia txog qhov sib txawv ntawm alpha beta gamma thiab delta coronavirus.
Summary - Alpha Beta Gamma vs Delta Coronavirus
Coronaviruses tau ntim cov kab mob zoo-xav tau ib leeg-stranded RNA kab mob. Muaj plaub yam tseem ceeb xws li Alphacoronavirus, Betacoronavirus, Gammacoronavirus thiab Deltacoronavirus. Alphacoronavirus thiab betacoronavirus kis rau tsiaj tsiaj, suav nrog tib neeg thaum gammacoronavirus thiab deltacoronavirus kis noog. Qhov no yog qhov sib txawv tseem ceeb ntawm alpha beta gamma thiab delta coronavirus. There are two human alphacoronaviruses (HCoV-229E and HCoV-NL63) while there are five human betacoronaviruses (HCoV-OC43, HCoV-HKU1, MERS-CoV, SARS-CoV and SARS-CoV2).
