Qhov Tseem Ceeb - Endosome vs Lysosome
Qhov sib txawv tseem ceeb ntawm Endosome thiab Lysosome yog nyob ntawm nws qhov tsim thiab nws txoj haujlwm hauv cell. Endosome yog tsim los ntawm endocytosis, whereas lub lysosome yog ib tug membrane khi vesicle uas muaj degrading hydrolytic enzymes.
Lub endosomal thiab lysosomal systems yog ib qho tseem ceeb hauv cellular degradation. Thaum cov molecule raug ntes los ntawm endocytosis, lawv tsim cov endosome. Endosome yog ib daim nyias nyias nyob rau hauv eukaryotic hlwb. Lub endosome ces fuses nrog lysosome kom degrade lub molecule los ntawm lysosomal hydrolytic enzymes.
Dab tsi yog Endosome?
Endosomes yog daim nyias nyias uas tau muab los ntawm plasma membrane vim cov txheej txheem ntawm endocytosis. Endocytosis yog cov txheej txheem los ntawm cov kua dej, kuab tshuaj, sib txawv macromolecules, plasma membrane Cheebtsam thiab ntau lwm yam hais nyob rau hauv. Lub plasma membrane tsim invagination, thiab lawv tsim vesicles los ntawm membrane fission. Cov vesicles no hu ua Endosomes. Endosomes feem ntau koom nrog hauv kev tswj kev lag luam ntawm cov protein thiab lipids hauv cell.
Endosomes tuaj yeem faib ua cov endosomes thaum ntxov, lig endosomes, thiab rov ua dua endosomes. Thaum ntxov endosomes yog thawj tsim. Thaum maturation los ntawm kev tso tawm cov khoom sib txawv xws li acids, lawv hloov mus rau hauv endosomes lig. Late endosomes ces fuse nrog lysosomes los tsim endolysosomes. Qhov fusion no ces yuav ua rau degradation ntawm lub molecule.
Daim duab 01: Endosome
Recycling endosomes muaj cov tubular zoo network thiab koom nrog hauv kev rov kaw cov molecules rov qab mus rau plasma membrane. Qhov no yog qhov tseem ceeb hauv kev rov ua dua cov protein.
YLysosome yog dab tsi?
Lysosomes yog daim nyias nyias khi organelles nyob rau hauv eukaryotic hlwb. Lysosomes muaj cov kua qaub hydrolases uas muaj peev xwm degrade biomolecules. Cov enzymes no tsuas yog ua haujlwm ntawm acidic pH.
Thaum molecules raug ntes ntawm endocytosis, lawv tsim endosomes. Yog li cov endosomes ces fuse nrog lysosomes pib degradation. Endolysosomes yog tsim los ntawm qhov fusion no. Precisely, lig endosomes uas muaj acidic pH fuse nrog lysosomes. Yog li, qhov txo qis acidic pH yuav, tig mus, qhib cov hydrolases uas yuav degrade cov molecules.
Daim duab 02: Lysosomes
Ntxiv rau qhov endocytosis, phagocytosis thiab autophagy tuaj yeem ua rau cov kab mob lysosomal. Phagocytic hlwb tuaj yeem fuse nrog lysosomes tsim Phagolysosomes uas tom qab ntawd dhau mus degradation. Thaum lub sij hawm autophagy, intracellular Cheebtsam yog compartmentalized rau hauv autophagosomes. Cov autophagosomes no fuse nrog lysosomes mus rau degradation ntawm cov tebchaw ua rau gradual cell tuag.
Dab tsi zoo sib xws ntawm Endosome thiab Lysosome?
- Ob leeg endosomes thiab lysosomes muaj nyob hauv eukaryotic hlwb.
- Ob leeg yog cov txheej txheem sib khi thiab pom nyob rau hauv lub cell cytoplasm.
- Ob leeg koom nrog hauv kev degradation ntawm cov tebchaw.
Qhov txawv ntawm Endosome thiab Lysosome yog dab tsi?
Endosome vs Lysosome |
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| Endosomes yog plasma membrane raws invaginations tsim los ntawm cov txheej txheem ntawm endocytosis. | Lysosomes yog cov membrane khi organelles uas muaj hydrolytic enzymes. |
| Endosomes yog tsim los ntawm endocytosis, qhov twg cov plasma membrane tsim invaginations los ntawm kev ntes cov molecule. Lub plasma membrane fission ua rau endosomes. | Lysosomes yog ib txwm muaj raws li daim nyias nyias khi organelles hauv cell cytoplasm. |
| Type | |
| Early endosome, lig endosome, recycling endosomes yog peb hom endosomes. | Endolysosome, Phagolysosome, Autophagolysosome yog peb hom lysosomes. |
| Muaj nuj nqi | |
| ntes cov biomolecules, kua dej, thiab cov kuab tshuaj thiab coj lawv mus rau degradation, protein recycling yog cov haujlwm ntawm endosomes. | Degradation ntawm molecules coj los ntawm endosomes thiab phagocytes, degradation los yog intracellular teeb meem coj los ntawm autophagy yog lub zog ntawm lysosomes. |
| pH Xwm txheej | |
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Summary – Endosome vs Lysosome
Endosomes thiab Lysosomes muaj nyob hauv eukaryotes. Endosomes yog tsim los ntawm endocytosis uas engulfs Cheebtsam xws li cov proteins thiab lipids los tsim plasma membrane raws li vesicles hu ua endosomes. Lysosomes, nyob rau hauv sib piv, yog organelles muaj acid hydrolases thiab koom nyob rau hauv lub degradation ntawm biomolecules thaum fused nrog endosomes, phagosomes los yog autophagosomes. Qhov no yog qhov txawv ntawm endosomes thiab lysosomes.
