Qhov Tseem Ceeb Qhov txawv - Leukemia vs Ntau Myeloma
Qhov sib txawv tseem ceeb ntawm Leukemia thiab Multiple Myeloma yog Leukemia yog cov ntshav yug los mob qog noj ntshav uas cov pob txha pob txha thiab lwm yam kabmob ua rau cov ntshav xws li tus po thiab cov qog ntshav ua rau cov ntshav tsis paub tab lossis txawv txav (cov qe ntshav dawb.) thaum Multiple myeloma yog ib hom ntshav tshwj xeeb yug qog noj ntshav uas txawv txav ntawm cov plasma hlwb proliferate thiab infiltrate cov ntshav tsim cov kab mob xws li cov pob txha pob txha, spleen thiab lymph nodes. Txawm li cas los xij, nyob rau hauv ntau yam myeloma, cov ntshav plasma txawv txav qee zaum tuaj yeem nchuav mus rau hauv cov ntshav, ua rau cov ntshav qog ntshav ntshav ntshav.
Leukemia yog dab tsi?
Leukemia lossis qhov txawv txav ntawm cov qe ntshav dawb tuaj yeem tshwm sim los ntawm txhua hom qe ntshav dawb.
- Lymphocytes - Lymphocytic leukemia
- Myelocytes - Myelocytic leukemia
- Eosinophils - Eosinophilic leukemia
Cov qog nqaij hlav no tuaj yeem mob hnyav lossis mob ntev thiab tuaj yeem sawv cev rau txhua theem ntawm cov qe ntshav dawb kom loj tuaj (piv txwv li blasts - mob lymphoblastic leukemia). Mob lymphoblastic leukemia feem ntau pom ntawm cov menyuam yaus thaum mob myeloid leukemia feem ntau pom ntawm cov neeg laus. Tus nqi ntawm kev loj hlob tuaj yeem sib txawv ntawm cov malignancies no. Leukemias tshwm sim los ntawm kev hloov caj ces uas tuaj yeem tshwm sim ntawm tus kheej lossis nrog cov exogenous stimuli xws li hluav taws xob thiab tshuaj lom. Kev nthuav qhia ntawm leukemia feem ntau tsis yog tshwj xeeb. Vim qhov kev loj hlob sai ntawm cov qe ntshav txawv txav, cov kab cell ntawm cov pob txha pob txha tau raug tshem tawm, ua rau cov hlwb txo qis (txo cov qe ntshav liab ua rau cov ntshav liab, txo cov platelets). Cov hlwb txawv txav tuaj yeem nkag mus rau lwm yam kabmob uas tsim cov ntshav xws li tus po, daim siab, thiab cov qog ntshav. Thaum tus kab mob hnyav heev, nws tuaj yeem cuam tshuam rau lwm yam kabmob uas tsis yog ntshav xws li lub hlwb, lub ntsws, thiab cov qog ntshav. Raws li qhov kev nthuav qhia tsis yog tshwj xeeb, ntau yam myeloma feem ntau kuaj pom lig.
Cov ntshav smear yooj yim hauv qab lub tshuab ntsuas pom tuaj yeem pom cov hlwb txawv txav thiab yuav muab qhov kev kuaj mob. Kev kuaj mob kom ntxaws ntxiv tuaj yeem ua tau siv cov txheej txheem qib siab xws li ntws cytometry thiab kev tiv thaiv kab mob histochemistry. Txhua tus neeg mob xav tau kev soj ntsuam kom zoo txog qhov twg ntawm tus kab mob. Kev kho mob suav nrog kev siv tshuaj khomob, kev kho hluav taws xob, kev kho lub hom phiaj, thiab hloov cov pob txha pob txha, ntxiv rau kev txhawb nqa thiab kev saib xyuas palliative raws li xav tau. Kev kwv yees nyob ntawm qhov kev hloov pauv caj ces thiab hom mob qog noj ntshav.
Ntau Myeloma yog dab tsi?
Ntau tus myeloma lossis qhov txawv txav ntawm cov plasma hlwb cuam tshuam nrog cov spectrum ntawm kev txawv txav uas suav nrog kev nce hauv cov ntshav calcium ntau ntxiv thiab nce cov ntshav tuab vim para-proteins secreted los ntawm cov ntshav plasma txawv txav. Tsis tas li ntawd, cov neeg mob no tau txais cov pob txha pob txha thaum cov plasma hlwb infiltrate cov pob txha pob txha. Thaum kawg lawv tuaj yeem mob raum tsis ua haujlwm vim muaj ntau yam laj thawj.
Kev kuaj mob ntawm ntau tus mob myeloma yog ua tiav nrog kev kuaj ntshav (cov ntshav protein electrophoresis, ntshav dawb kappa / lambda lub teeb saw teeb), zis protein electrophoresis, kuaj pob txha pob txha, thiab X-rays ntawm cov pob txha. Ntau myeloma yog kho tsis tau, tab sis nws kho tau. Kev tso tawm tuaj yeem raug ntxias nrog cov tshuaj steroids, tshuaj khomob, tshuaj tiv thaiv kab mob xws li thalidomide lossis lenalidomide, thiab qia cell hloov. Kev kho hluav taws xob qee zaum siv los txo qhov mob ntawm pob txha pob txha.
Dab tsi yog qhov txawv ntawm Leukemia thiab Multiple Myeloma?
txhais ntawm Leukemia thiab Ntau Myeloma
Leukemia: Leukemia yog cov ntshav yug los mob qog noj ntshav uas cov pob txha pob txha thiab lwm yam kabmob ua rau cov ntshav tsim cov leukocytes tsis paub tab lossis txawv txav.
Multiple myeloma: Ntau tus myeloma yog ib hom ntshav tshwj xeeb yug qog noj ntshav uas txawv txav plasma cells proliferate thiab nkag mus rau hauv cov ntshav tsim cov kabmob xws li cov pob txha pob txha, spleen thiab lymph nodes.
Tus yam ntxwv ntawm Leukemia thiab Ntau Yam Myeloma
Pathophysiological Basis
Leukemia: Leukemia raug xa mus rau qhov kev loj hlob ntawm cov qe ntshav dawb xws li lymphocytes thiab Myelocytes.
Ntau tus kab mob myeloma: Myeloma raug xa mus rau qhov kev loj hlob ntawm cov ntshav plasma.
Hnub nyoog Distribution
Leukemia: Leukemia tuaj yeem tshwm sim hauv txhua pab pawg hnub nyoog.
Multiple myeloma: Myeloma tshwm sim hauv cov neeg laus.
Kev nyuaj siab
Leukemia: Leukemia feem ntau tsis ua rau lub raum tsis ua haujlwm, hyperkalemia, thiab paraproteinemia.
Ntau tus myeloma: Myeloma ua rau lub raum tsis ua haujlwm, hyperkalemia, thiab paraproteinemia.
Diagnosis
Leukemia: Leukemia yog kuaj los ntawm cov duab ntshav, ntws cytometry, thiab tiv thaiv kab mob histochemistry.
Multiple myeloma: Myeloma raug kuaj pom muaj cov ntshav protein electrophoresis, ntshav dawb kappa/lambda lub teeb saw teeb), kuaj pob txha, zis protein electrophoresis, thiab X-rays ntawm pob txha.
Kev kho mob
Leukemia: Leukemia yog kho nrog chemoradiation.
Multiple myeloma: Myeloma yog kho nrog steroids thiab immunomodulatory agents xws li thalidomide lossis lenalidomide.
Kev Tshawb Fawb
Leukemia: Leukemia muaj qhov tshwm sim sib txawv. Qee hom leukemias tuaj yeem kho tau.
Multiple myeloma: Myeloma feem ntau muaj cov tsos mob tsis zoo thiab xav tias yuav kho tsis tau.
Image Courtesy: "Cov tsos mob ntawm leukemia" los ntawm Mikael Häggström - Tag nrho cov duab siv yog nyob rau hauv pej xeem sau.(Public Domain) ntawm Commons "Blausen 0656 MultipleMyeloma" los ntawm Blausen Medical Communications, Inc. - Pub dawb ntawm OTRS, saib daim pib kom paub meej.(CC BY 3.0) via Commons
